Chemical Safety Data Sheet MSDS / SDS
DIATOMACEOUS EARTH
Revision Date:2026-03-21Revision Number:1
Product identifier
- Product name: DIATOMACEOUS EARTH
- CBnumber: CB4199395
- CAS: 68855-54-9
- EINECS Number: 272-489-0
- Synonyms: Hyflow;CELITE 521
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P314 Get medical advice/attention if you feel unwell.
P501 Dispose of contents/container to..…
Hazard statements
H372 Causes damage to organs through prolonged or repeated exposure
Substance
- Product name: DIATOMACEOUS EARTH
- Synonyms: Hyflow;CELITE 521
- CAS: 68855-54-9
- EC number: 272-489-0
- MF: O2Si
- MW: 60.084
4.1 Description of first-aid measures
General adviceShow this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. Call in physician.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower.
In case of eye contact
After eye contact: rinse out with plenty of water. Remove contact lenses.
If swallowed
After swallowing: immediately make victim drink water (two glasses at most). Consult a physician.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
4.4 Notes to physician
No data available
5.1 Extinguishing media
Suitable extinguishing mediaUse extinguishing measures that are appropriate to local circumstances and the surrounding environment.
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
5.2 Special hazards arising from the substance or mixture
silicon oxides
Not combustible.
Ambient fire may liberate hazardous vapours.
Not combustible.
Ambient fire may liberate hazardous vapours.
5.3 Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.
NFPA 704
1
0
0
| HEALTH | 1 | Exposure would cause irritation with only minor residual injury (e.g. acetone, sodium bromate, potassium chloride) | |
| FIRE | 0 | Materials that will not burn under typical fire conditions, including intrinsically noncombustible materials such as concrete, stone, and sand. Materials that will not burn in air when exposed to a temperature of 820 °C (1,500 °F) for a period of 5 minutes.(e.g. Carbon tetrachloride) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
6.1 Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Avoid generation and inhalation of dusts in all circumstances. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains.
6.3 Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up dry. Dispose of properly. Clean up affected area. Avoid generation of dusts.
6.4 Reference to other sections
For disposal see section 13.
7.1 Precautions for safe handling
Advice on safe handlingWork under hood. Do not inhale substance/mixture.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
For precautions see section 2.2.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditionsTightly closed. Dry. Keep in a well-ventilated place. Keep locked up or in an area accessible only to qualified or authorized persons.
Storage class
Storage class (TRGS 510): 6.1D: Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
8.1 Control parameters
Ingredients with workplace control parameters| ['Component', 'CAS-No.', 'Value', 'Control\nparameters', 'Basis'] | ['cristobalite', '14464-46-\n1', 'TWA', '0.025 mg/m3', 'USA. ACGIH Threshold Limit\nValues (TLV)'] | ['', 'Remarks', 'Suspected human carcinogen', None, None] | ['', '', 'TWA', '0.025 mg/m3', 'USA. ACGIH Threshold Limit\nValues (TLV)'] | ['', '', 'Lung cancer\nPulmonary fibrosis\nSuspected human carcinogen', None, None] | ['', '', 'Use ½ the value calculated from the count or mass formula\nfor quartz.', None, None] | ['', '', 'TWA', '0.05 mg/m3', 'USA. Table Z-1-A Limits for Air\nContaminants (1989 vacated\nvalues)'] |
|---|
8.2 Exposure controls
Appropriate engineering controlsImmediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Skin protection
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:KCL 741 L
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:KCL 741 L
Body Protection
Internet: www.kcl.de).
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:KCL 741 L
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 480 min
Material tested:KCL 741 L
protective clothing
Respiratory protection
required when dusts are generated.
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Control of environmental exposure
Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Do not let product enter drains.
Information on basic physicochemical properties
- a) Physical statesolid
- b) Colorwhite
- c) OdorNo data available
- d) Melting point/freezing pointNo data available
- e) Initial boiling point and boiling rangeNo data available
- f) Flammability (solid, gas)The product is not flammable.
- g) Upper/lower flammability or explosive limitsNo data available
- h) Flash pointNo data available
- i) Autoignition temperatureNot applicable
- j) Decomposition temperatureNo data available
- k) pH>8.5 (25℃, 10% in aq. suspension)
- l) ViscosityViscosity, kinematic: No data available
Viscosity, dynamic: No data available - m) Water solubilityInsoluble in water.
- n) Partition coefficient n-octanol/waterNo data available
- o) Vapor pressureNo data available
- p) Density0.47 g/cm3 (loose weight)(lit.)
- Relative density0.47 g/cm3 (loose weight)(lit.)
- q) Relative vapor densityNo data available
- r) Particle characteristicsNo data available
- s) Explosive propertiesNot classified as explosive.
- t) Oxidizing propertiesnone
- Solubility<0.001g/l
9.2 Other safety information
No data available
10.1 Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
10.2 Possibility of hazardous reactions
No data available
10.3 Conditions to avoid
no information available
10.4 Incompatible materials
Hydrogen fluoride
10.5 Hazardous decomposition products
In the event of fire: see section 5
11.1 Information on toxicological effects
Mixture Acute toxicityOral: No data available
Inhalation: No data available
Dermal: No data available
Skin corrosion/irritation
Inhalation: No data available
Dermal: No data available
Classified based on available data. For more details, see section 2
Serious eye damage/eye irritation
Classified based on available data. For more details, see section 2
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Classified based on available data. For more details, see section 2
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Mixture causes damage to organs through prolonged or repeated exposure.
- Lungs
Aspiration hazard
- Lungs
Classified based on available data. For more details, see section 2
11.2 Additional Information
Prolonged inhalation of crystalline silica may result in silicosis, a disabling pulmonary fibrosis characterized by fibrotic changes and miliary nodules in the lungs, a dry cough, shortness of breath, emphysema, decreased chest expansion, and increased susceptibility to tuberculosis. In advanced stages, loss of appetite, pleuritic pain, and total incapacity to work. Advanced silicosis may result in death due to cardiac failure or destruction of lung tissue. Crystalline silica is classified as group 1 "known to be carcinogenic to humans" by
IARC and "sufficient evidence" of carcinogenicity by the NTP., The chronic health risks are associated with respirable particles of 3-4 um over protracted periods of time. Currently, there is a limited understanding of the mechanisms of quartz toxicity, including its mechanisms for lung carcinogenicity. Additional studies are needed to determine whether the cell transforming activity of quartz is related to its carcinogenic potential., Respirable silica may cause immune system disorders, increased risk to develop pulmonary tuberculosis, and increased incidence of kidney disease.
Other dangerous properties can not be excluded.
Handle in accordance with good industrial hygiene and safety practice.
Components Kieselguhr (contains free crystalline silicic acid)
IARC and "sufficient evidence" of carcinogenicity by the NTP., The chronic health risks are associated with respirable particles of 3-4 um over protracted periods of time. Currently, there is a limited understanding of the mechanisms of quartz toxicity, including its mechanisms for lung carcinogenicity. Additional studies are needed to determine whether the cell transforming activity of quartz is related to its carcinogenic potential., Respirable silica may cause immune system disorders, increased risk to develop pulmonary tuberculosis, and increased incidence of kidney disease.
Other dangerous properties can not be excluded.
Handle in accordance with good industrial hygiene and safety practice.
Acute toxicity
LD50 Oral - Rat - female - > 2,000 mg/kg (OECD Test Guideline 401)
LC50 Inhalation - Rat - male and female - 4 h - > 2.6 mg/l - dust/mist (OECD Test Guideline 403)
Symptoms: Chronic intoxication:, Pneumokoniosis (silicosis)
Dermal: No data available
LC50 Inhalation - Rat - male and female - 4 h - > 2.6 mg/l - dust/mist (OECD Test Guideline 403)
Symptoms: Chronic intoxication:, Pneumokoniosis (silicosis)
Dermal: No data available
Skin corrosion/irritation
Skin - reconstructed human epidermis (RhE)
Result: No skin irritation - 4 h (OECD Test Guideline 431)
Result: No skin irritation - 4 h (OECD Test Guideline 431)
Serious eye damage/eye irritation
Eyes - Rabbit
Result: No eye irritation (OECD Test Guideline 405)
Result: No eye irritation (OECD Test Guideline 405)
Respiratory or skin sensitization
Local lymph node assay (LLNA) - Mouse
Result: negative (OECD Test Guideline 429)
Germ cell mutagenicity
Result: negative (OECD Test Guideline 429)
Test Type: Ames test
Test system: Escherichia coli/Salmonella typhimurium
Result: negative
Test Type: Mutagenicity (mammal cell test): chromosome aberration.
Test system: lymphocyte
Result: negative
Test Type: In vitro mammalian cell gene mutation test
Test system: mouse lymphoma cells
Result: negative
Carcinogenicity
Test system: Escherichia coli/Salmonella typhimurium
Result: negative
Test Type: Mutagenicity (mammal cell test): chromosome aberration.
Test system: lymphocyte
Result: negative
Test Type: In vitro mammalian cell gene mutation test
Test system: mouse lymphoma cells
Result: negative
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Acute inhalation toxicity - Chronic intoxication:, Pneumokoniosis (silicosis)
Specific target organ toxicity - repeated exposure
Inhalation - Causes damage to organs through prolonged or repeated exposure.
- Lungs
Aspiration hazard
- Lungs
Classified based on available data. For more details, see section 2
cristobalite Acute toxicity
Oral: No data available
Inhalation: No data available
Dermal: No data available
Skin corrosion/irritation
Inhalation: No data available
Dermal: No data available
Classified based on available data. For more details, see section 2
Serious eye damage/eye irritation
Classified based on available data. For more details, see section 2
Respiratory or skin sensitization
Classified based on available data. For more details, see section 2
Germ cell mutagenicity
Classified based on available data. For more details, see section 2
Carcinogenicity
Classified based on available data. For more details, see section 2
Reproductive toxicity
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Classified based on available data. For more details, see section 2
Specific target organ toxicity - repeated exposure
Inhalation - Causes damage to organs through prolonged or repeated exposure.
- Lungs
Aspiration hazard
- Lungs
Classified based on available data. For more details, see section 2
12.1 Toxicity
MixtureNo data available
12.2 Persistence and degradability
No data available
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
12.6 Endocrine disrupting properties
No data available
12.7 Other adverse effects
No data available
Components Kieselguhr (contains free crystalline silicic acid)
Toxicity to fish semi-static test LC50 - Oncorhynchus mykiss (rainbow trout) - > 50 mg/l - 96 h (OECD Test Guideline 203)
Remarks: (above the solubility limit in the test medium)
Toxicity to daphnia static test EC50 - Daphnia magna (Water flea) - > 50 mg/l - and other aquatic 48 h invertebrates (OECD Test Guideline 202)
Toxicity to algae ErC50 - Desmodesmus subspicatus (green algae) - > 50 mg/l - 72 h (OECD Test Guideline 201)
Remarks: (above the solubility limit in the test medium)
Toxicity to bacteria EC50 - activated sludge - > 1,000 mg/l - 3 h (OECD Test Guideline 209)
Remarks: (above the solubility limit in the test medium)
cristobalite
Remarks: (above the solubility limit in the test medium)
Toxicity to daphnia static test EC50 - Daphnia magna (Water flea) - > 50 mg/l - and other aquatic 48 h invertebrates (OECD Test Guideline 202)
Toxicity to algae ErC50 - Desmodesmus subspicatus (green algae) - > 50 mg/l - 72 h (OECD Test Guideline 201)
Remarks: (above the solubility limit in the test medium)
Toxicity to bacteria EC50 - activated sludge - > 1,000 mg/l - 3 h (OECD Test Guideline 209)
Remarks: (above the solubility limit in the test medium)
No data available
13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company.
Offer surplus and non-recyclable solutions to a licensed disposal company.
14.1 UN number
ADR/RID: -
IMDG: -
IATA-DGR: -
IMDG: -
IATA-DGR: -
14.2 UN proper shipping name
ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA-DGR: Not dangerous goods
IMDG: Not dangerous goods
IATA-DGR: Not dangerous goods
14.3 Transport hazard class(es)
ADR/RID: -
IMDG: -
IATA-DGR: -
IMDG: -
IATA-DGR: -
14.4 Packaging group
ADR/RID: -
IMDG: -
IATA-DGR: -
IMDG: -
IATA-DGR: -
14.5 Environmental hazards
ADR/RID: no
IMDG Marine pollutant: no
IATA-DGR: no
IMDG Marine pollutant: no
IATA-DGR: no
14.6 Special precautions for user
14.7 Incompatible materials
Hydrogen fluoride
Further information: Not classified as dangerous in the meaning of transport regulations.
Further information: Not classified as dangerous in the meaning of transport regulations.
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
National regulatory information
Law on the Prevention and Control of Occupational Diseases
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Law on the Prevention and Control of Occupational Diseases
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Abbreviations and acronyms
CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.