Chemical Safety Data Sheet MSDS / SDS
Chlordecone
Revision Date:2026-04-26Revision Number:1
Product identifier
- Product name: Chlordecone
- CBnumber: CB8426282
- CAS: 143-50-0
- EINECS Number: 205-601-3
- Synonyms: Chlordecone,Kepone
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
P501 Dispose of contents/container to..…
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P273 Avoid release to the environment.
Hazard statements
H351 Suspected of causing cancer
H410 Very toxic to aquatic life with long lasting effects
H301 Toxic if swalloed
H311 Toxic in contact with skin
Substance
- Product name: Chlordecone
- Synonyms: Chlordecone,Kepone
- CAS: 143-50-0
- EC number: 205-601-3
- MF: C10Cl10O
- MW: 490.64
First Aid Measures
General adviceImmediate medical attention is required.
Eye contact
Immediately flush with plenty of water. After initial flushing, remove any contact lenses and continue flushing for at least 15 minutes. Keep eye wide open while rinsing. Call a physician immediately.
Skin Contact
Immediate medical attention is required. Wash off immediately with soap and plenty of water while removing all contaminated clothes and shoes.
Inhalation
Immediate medical attention is required Remove to fresh air If not breathing, give artificial respiration Avoid direct contact with skin. Use barrier to give mouth-to-mouth resuscitation
Ingestion
Do NOT induce vomiting. Call a physician or poison control center immediately. Never give anything by mouth to an unconscious person. Drink plenty of water.
Self-protection of the first aider
Use personal protective equipment as required. Avoid contact with skin, eyes or clothing.
Most important symptoms and effects, both acute and delayed
SymptomsNo information available.
Indication of any immediate medical attention and special treatment needed
Note to physiciansTreat symptomatically.
Suitable Extinguishing Media
Suitable Extinguishing MediaUse extinguishing measures that are appropriate to local circumstances and the surrounding environment.
Unsuitable Extinguishing Media
No information available.
Specific hazards arising from the chemical
Specific hazards arising from the chemicalThermal decomposition can lead to release of toxic/corrosive gases and vapors.
Hazardous combustion products
Carbon oxides. Phosgene.
Explosion data
Sensitivity to Mechanical ImpactNo information available.
Sensitivity to Static Discharge
No information available.
Protective equipment and precautions for firefighters
Protective equipment and precautions for firefightersAs in any fire, wear self contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear.
Personal precautions, protective equipment and emergency procedures
Personal precautionsUse personal protective equipment as required. Keep people away from and upwind of spill/leak.
Environmental precautions
Environmental precautionsPrevent further leakage or spillage if safe to do so. Prevent product from entering drains.
See Section 12 for additional Ecological Information.
See Section 12 for additional Ecological Information.
Methods and material for containment and cleaning up
Methods for containmentPrevent further leakage or spillage if safe to do so. Cover powder spill with plastic sheet or tarp to minimize spreading. Dike far ahead of liquid spill for later disposal.
Methods for cleaning up
Use personal protective equipment as required. Take up mechanically, placing in appropriate containers for disposal. Clean contaminated surface thoroughly. Cover powde spill with plastic sheet or tarp to minimize spreading and keep powder dry. Avoid creating dust.
Precautions for safe handling
Advice on safe handlingAvoid contact with skin, eyes or clothing. Use personal protective equipment as required.
Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray.
Do not eat, drink or smoke when using this product. Thermal decomposition can lead to release of toxic/corrosive gases and vapors.
Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray.
Do not eat, drink or smoke when using this product. Thermal decomposition can lead to release of toxic/corrosive gases and vapors.
Conditions for safe storage, including any incompatibilities
Storage ConditionsKeep container tightly closed in a dry and well-ventilated place. Keep out of the reach of children. Store at room temperature.
Incompatible materials
None known based on information supplied.
Control parameters
Exposure Guidelines.
| Column 1 | Column 2 | Column 3 | Column 4 |
|---|---|---|---|
| Chlordecone 143-50-0 | - | - | TWA: 0.001 mg/m3 |
Appropriate engineering controls
Engineering ControlsShowers
Eyewash stations
Ventilation systems
Eyewash stations
Ventilation systems
Individual protection measures, such as personal protective equipment
Eye/face protectionTight sealing safety goggles.
Skin and Body Protection
Wear protective gloves and protective clothing.
Respiratory protection
If exposure limits are exceeded or irritation is experienced, NIOSH/MSHA approved respiratory protection should be worn. Positive-pressure supplied air respirators may be required for high airborne contaminant concentrations. Respiratory protection must be provided in accordance with current local regulations.
General Hygiene Considerations
When using do not eat, drink or smoke. Regular cleaning of equipment, work area and clothing is recommended. Avoid contact with skin, eyes or clothing. Wash hands thoroughly after handling. Keep away from food, drink and animal feeding stuffs.
Information on basic physicochemical properties
- Physical StateSolid
- AppearanceNo information available
- OdorNo information available
- pHNo information available
- Melting point/freezing point147.33 °C
- Boiling point450.5 °C
- Flash point100 °C
- Liquid Density2.3 g/cm3
- Evaporation rateNo information available
- Upper flammability limitsNo information available
- Lower flammability limitNo information available
- Vapor pressure0.0 mmHg
- Vapor density19.65
- Specific gravityNo information available
- Water solubility(mg/L):
7.600 at 24 °C (shake flask-nephelometry, Hollifield, 1979)
2.7 at 20–25 °C (Kilzer et al., 1979) - Solubility in other solventsNo information available
- Partition coefficient3.86
- Autoignition temperatureNo information available
- Decomposition temperatureNo information available
- Kinematic viscosityNo information available
- Explosive propertiesNo information available
- Oxidizing propertiesNo information available
- Density and/or relative density2.27
- SolubilitySoluble in acetic acid, alcohols, and ketones (Windholz et al., 1983)
- Henry's Law Constant(x 10-2 atmm3/mol): 3.11 at 25 °C (approximate - calculated from experimentally determined water solubility and vapor pressure values)
Reactivity
Not applicable
Chemical stability
Stable under recommended storage conditions.
Possibility of Hazardous Reactions
None under normal processing.
Hazardous polymerization
No information available.
Conditions to avoid
Extremes of temperature and direct sunlight.
Incompatible materials
Strong oxidizing agents.
Hazardous Decomposition Products
Carbon oxides. Phosgene.
Information on likely routes of exposure
InhalationClassified based on available data. For more details, see section 2.
Eye contact
Classified based on available data. For more details, see section 2.
Skin Contact
Classified based on available data. For more details, see section 2.
Ingestion
Classified based on available data. For more details, see section 2.
Information on toxicological effects
SymptomsClassified based on available data. For more details, see section 2.
Delayed and immediate effects as well as chronic effects from short and long-term exposure
Chronic ToxicityMay cause adverse liver effects. Contains a known or suspected reproductive toxin. Target Organ Effects Reproductive System, Central nervous system, Eyes, Respiratory system, Kidney, Liver, Skin. Carcinogenicity The table below indicates whether each agency has listed any ingredient as a carcinogen.
Chemical name ACGIH IARC NTP OSHA
Chlordecone - Group2A Reasonably Anticipated X 143-50-0 Group 2B
IARC (International Agency for Research on Cancer) Group 2A - Probably Carcinogenic to Humans
Group2B - Possibly Carcinogenic to Humans
Numerical measures of toxicity - Product Information
Unknown acute toxicityClassified based on available data. For more details, see section 2
The following values are calculated based on chapter 3.1 of the GHS document
ATEmix (oral)
The following values are calculated based on chapter 3.1 of the GHS document
91 mg/kg
ATEmix (dermal)
300 mg/kg
Ecotoxicity
Very toxic to aquatic life with long lasting effects
0% of the mixture consists of components(s) of unknown hazards to the aquatic environment.
0% of the mixture consists of components(s) of unknown hazards to the aquatic environment.
Persistence and degradability
No information available.
Bioaccumulation
No information available.
Mobility
No information available.
Chlordecone
5.3 143-50-0
Disposal of wastes
Disposal should be in accordance with applicable regional, national and local laws and regulations.
Contaminated packaging
Do not reuse container.
Other Information
Waste codes should be assigned by the user based on the application for which the product was used.
US EPA Waste Number
U142
California Hazardous Waste Status
This product contains one or more substances that are listed with the State of California as a hazardous waste.
| Chemical name | California Hazardous Waste Status |
|---|---|
| Chlordecone 143-50-0 | Toxic |
DOT
UN/ID noUN2811
Hazard Class
6.1
Packing Group
III
Proper shipping name
Toxic solids, organic, n.o.s. Reportable Quantity (RQ) (Chlordecone: RQ (kg)= 0.454)
Description
UN2811, Toxic solids, organic, n.o.s. (Chlordecone), 6.1, III
Emergency Response Guide Number
154
IMDG
UN/ID noUN2811
Hazard Class
6.1
Packing Group
III
Proper shipping name
Toxic solid, organic, n.o.s.
Description
UN2811, Toxic solid, organic, n.o.s. (Chlordecone), 6.1, III, Marine pollutant
Special Provisions
223, 274
EmS-No
F-A, S-A
IATA
UN/ID noUN2811
Hazard Class
6.1
Packing Group
III
Proper shipping name
Toxic solid, organic, n.o.s.
Description
UN2811, Toxic solid, organic, n.o.s. (Chlordecone), 6.1, III
ERG Code
6L
International Inventories
All of the components in the product are on the following Inventory lists
Europe (EINECS/ELINCS/NLP) Australia (AICS) Philippines (PICCS)
X - Listed
TSCA - United States Toxic Substances Control Act Section 8(b) Inventory
DSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances List
EINECS/ELINCS - European Inventory of Existing Chemical Substances/European List of Notified Chemical Substances
ENCS - Japan Existing and New Chemical Substances
IECSC - China Inventory of Existing Chemical Substances
KECL - Korean Existing and Evaluated Chemical Substances
PICCS - Philippines Inventory of Chemicals and Chemical Substances
Europe (EINECS/ELINCS/NLP) Australia (AICS) Philippines (PICCS)
X - Listed
TSCA - United States Toxic Substances Control Act Section 8(b) Inventory
DSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances List
EINECS/ELINCS - European Inventory of Existing Chemical Substances/European List of Notified Chemical Substances
ENCS - Japan Existing and New Chemical Substances
IECSC - China Inventory of Existing Chemical Substances
KECL - Korean Existing and Evaluated Chemical Substances
PICCS - Philippines Inventory of Chemicals and Chemical Substances
| Chemical name | TSCA | DSL | NDSL | EINECS | ELINCS | ENCS | IECSC | KECL | PICCS | AICS |
|---|---|---|---|---|---|---|---|---|---|---|
| Chlordecone | - | - | - | X | - | - | - | - | X | X |
US Federal Regulations
SARA 313
Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA). This product does not contain any chemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372.
SARA 311/312 Hazard Categories
Acute health hazardYes
Chronic Health Hazard
Yes
Fire hazard
No
Sudden release of pressure hazard
No
Reactive hazard
No
CWA (Clean Water Act)
This product contains the following substances which are regulated pollutants pursuant to the Clean Water Act (40 CFR 122.21 and 40 CFR 122.42).
| Chemical name | CWA - Reportable Quantities | CWA - Toxic Pollutants | CWA - Priority Pollutants | CWA - Hazardous Substances |
|---|---|---|---|---|
| Chlordecone 143-50-0 | 1 lb | X |
US State Regulations
California Proposition 65
This product contains the following Proposition 65 chemicals.
| Chemical name | California Proposition 65 |
|---|---|
| Chlordecone - 143-50-0 | Carcinogen Developmental |
U.S. State Right-to-Know Regulations
| Chemical name | New Jersey | Massachusetts | Pennsylvania |
|---|---|---|---|
| Chlordecone 143-50-0 | X | X | X |
Abbreviations and acronyms
CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.