Chemical Safety Data Sheet MSDS / SDS

Cyclopropanecarbonyl Chloride

Revision Date:2023-12-07Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

Product name: Cyclopropanecarbonyl Chloride
CBnumber: CB3667527
CAS: 4023-34-1
EINECS Number: 223-684-4
Synonyms: cyclopropanecarbonyl chloride,CYCLOPROPANECARBOXYLIC ACID CHLORIDE

Relevant identified uses of the substance or mixture and uses advised against

Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
Uses advised against: none

Company Identification

Company: Chemicalbook
Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
Telephone: 400-158-6606

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

Symbol(GHS)

Signal wordDanger

Precautionary statements

P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233 Keep container tightly closed.

P240 Ground/bond container and receiving equipment.

P260 Do not breathe dust/fume/gas/mist/vapours/spray.

P264 Wash hands thoroughly after handling.

P264 Wash skin thouroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P309 IF exposed or if you feel unwell:

P310 Immediately call a POISON CENTER or doctor/physician.

P370+P378 In case of fire: Use … for extinction.

P403+P235 Store in a well-ventilated place. Keep cool.

P405 Store locked up.

P501 Dispose of contents/container to..…

Hazard statements

H226 Flammable liquid and vapour

H301 Toxic if swalloed

H314 Causes severe skin burns and eye damage

H318 Causes serious eye damage

SECTION 3: Composition/information on ingredients

Substance

Product name: Cyclopropanecarbonyl Chloride
Synonyms: cyclopropanecarbonyl chloride,CYCLOPROPANECARBOXYLIC ACID CHLORIDE
CAS: 4023-34-1
EC number: 223-684-4
MF: C4H5ClO
MW: 104.53

SECTION 4: First aid measures

Description of first aid measures

General advice

Consult a physician. Show this material safety data sheet to the doctor in attendance.

If inhaled

If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

In case of skin contact

Take off contaminated clothing and shoes immediately. Wash off with soap and plenty of water. Consult a physician.

In case of eye contact

Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

If swallowed

Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11

Indication of any immediate medical attention and special treatment needed

No data available

SECTION 5: Firefighting measures

Extinguishing media

Suitable extinguishing media

Small (incipient) fires must be extinguished with alcohol resistant foam, dry chemical

Special hazards arising from the substance or mixture

Carbon oxides, Hydrogen chloride gas

Advice for firefighters

Wear self-contained breathing apparatus for firefighting if necessary.

Further information

Use water spray to cool unopened containers.

NFPA 704

HEALTH	3	Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid)
FIRE	2	Must be moderately heated or exposed to relatively high ambient temperature before ignition can occur and multiple finely divided suspended solids that do not require heating before ignition can occur. Flash point between 37.8 and 93.3 °C (100 and 200 °F). (e.g. diesel fuel, sulfur)
REACT	2	Undergoes violent chemical change at elevated temperatures and pressures, reacts violently with water, or may form explosive mixtures with water (e.g. white phosphorus, potassium, sodium)
SPEC. HAZ.	W

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapors accumulating to form explosive concentrations. Vapors can accumulate in low areas.

For personal protection see section 8.

Environmental precautions

Prevent further leakage or spillage if safe to do so. Do not let product enter drains.

Methods and materials for containment and cleaning up

Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet- brushing and place in container for disposal according to local regulations (see section 13).

Reference to other sections

For disposal see section 13.

SECTION 7: Handling and storage

Precautions for safe handling

Avoid inhalation of vapor or mist.

Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge.

For precautions see section 2.2.

Conditions for safe storage, including any incompatibilities

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

Recommended storage temperature 2 - 8 °C Store under inert gas. Moisture sensitive.

Specific end use(s)

Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

control parameter

Hazard composition and occupational exposure limits

Does not contain substances with occupational exposure limits.

Exposure controls

Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

Personal protective equipment

Eye/face protection

Tightly fitting safety goggles. Faceshield (8-inch minimum). Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.

The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.

Body Protection

Complete suit protecting against chemicals, Flame retardant antistatic protective clothing., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.

Respiratory protection

Where risk assessment shows air-purifying respirators are appropriate use a full- face respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).

Control of environmental exposure

Prevent further leakage or spillage if safe to do so. Do not let product enter drains.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

Appearance clear, liquid
OdourNo data available
Odour ThresholdNo data available
pHNo data available
Melting point/freezing point77.5-78.5 °C(Solv: hexane (110-54-3))
Initial boiling point and boiling range 119 °C - lit.
Flash point23 °C - closed cup
Evaporation rateNo data available
Flammability (solid, gas)No data available
Upper/lower flammability or explosive limitsNo data available
Vapour pressure No data available
Vapour density No data available
Relative density1,152 g/cm3 at 25 °C
Water solubilityNo data available
Partition coefficient: n-octanol/waterNo data available
Autoignition temperatureNo data available
Decomposition temperatureNo data available
ViscosityNo data available
Explosive propertiesNo data available
Oxidizing propertiesNo data available

Other safety information

No data available

SECTION 10: Stability and reactivity

Reactivity

No data available

Chemical stability

Stable under recommended storage conditions.

Possibility of hazardous reactions

No data available

Conditions to avoid

Heat, flames and sparks.

Incompatible materials

Strong oxidizing agents, Strong bases, Alcohols

Hazardous decomposition products

Hazardous decomposition products formed under fire conditions. - Carbon oxides, Hydrogen chloride gas

Other decomposition products - No data available In the event of fire: see section 5

SECTION 11: Toxicological information

Information on toxicological effects

Acute toxicity

LD50 Oral - Rat - 200 mg/kg Remarks: (External MSDS) absorption

Skin corrosion/irritation

Skin - Rabbit
Result: Causes burns. Remarks: (External MSDS)

Serious eye damage/eye irritation

Eyes - Rabbit
Result: Causes burns. Remarks: (External MSDS) Causes serious eye damage.

Respiratory or skin sensitization Germ cell mutagenicity Carcinogenicity

IARC: No ingredient of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.

Reproductive toxicity

Specific target organ toxicity - single exposure

Acute oral toxicity - If ingested, severe burns of the mouth and throat, as well as a danger of perforation of the esophagus and the stomach.
Acute inhalation toxicity - Shortness of breath, Cough, mucosal irritations, Possible damages:, damage of respiratory tract

Specific target organ toxicity - repeated exposure Aspiration hazard

Additional Information

RTECS: Not available
Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and skin., Cough, Shortness of breath, Headache, Nausea
Decomposition of the substance with tissue moisture. Other dangerous properties can not be excluded.
Handle in accordance with good industrial hygiene and safety practice.

Toxicity

LD50 orally in Rabbit: 200 mg/kg

SECTION 12: Ecological information

Toxicity

Toxicity to fish

LC50 - Fish - 850 mg/l - 96 h

Remarks: (External MSDS)

Toxicity to daphnia and other aquatic invertebrates

EC50 - Daphnia magna (Water flea) - 250 mg/l - 24 h Remarks: (External MSDS)

Toxicity to algae

IC50 - Desmodesmus subspicatus (green algae) - 290 mg/l - 5 d Remarks: (External MSDS)

Persistence and degradability

Bioaccumulative potential

Mobility in soil

Results of PBT and vPvB assessment

PBT/vPvB assessment not available as chemical safety assessment not required/not conducted

Other adverse effects

Harmful effect due to pH shift.

Possible decomposition products in case of hydrolyzis are:

hydrochloric acid

Discharge into the environment must be avoided.

SECTION 13: Disposal considerations

Waste treatment methods

Product

Burn in a chemical incinerator equipped with an afterburner and scrubber but exert extra care in igniting as this material is highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional waste disposal service to dispose of this material.

Contaminated packaging

Dispose of as unused product.

SECTION 14: Transport information

UN number

ADR/RID: 2920 IMDG: 2920 IATA: 2920

UN proper shipping name

ADR/RID: CORROSIVE LIQUID, FLAMMABLE, N.O.S. (cyclopropanecarboxylic acid chloride) IMDG: CORROSIVE LIQUID, FLAMMABLE, N.O.S. (cyclopropanecarboxylic acid chloride) IATA: Corrosive liquid, flammable, n.o.s. (cyclopropanecarboxylic acid chloride)

Transport hazard class(es)

ADR/RID: 8 (3) IMDG: 8 (3) IATA: 8 (3)

Packaging group

ADR/RID: II IMDG: II IATA: II

Environmental hazards

ADR/RID: no IMDG Marine pollutant: no IATA: no

Special precautions for user

No data available

SECTION 15: Regulatory information

Safety, health and environmental regulations/legislation specific for the substance or mixture

Regulations on the Safety Management of Hazardous Chemicals

China Catalog of Hazardous chemicals 2015:Not Listed. website: https://www.mem.gov.cn/

Measures for Environmental Management of New Chemical Substances

Chinese Chemical Inventory of Existing Chemical Substances (China IECSC):Listed. website: https://www.mee.gov.cn/

EC Inventory:Listed.

European Inventory of Existing Commercial Chemical Substances (EINECS):Listed. website: https://echa.europa.eu/

Korea Existing Chemicals List (KECL):Listed. website: http://ncis.nier.go.kr

New Zealand Inventory of Chemicals (NZIoC):Listed. website: https://www.epa.govt.nz/

United States Toxic Substances Control Act (TSCA) Inventory:Listed. website: https://www.epa.gov/

Vietnam National Chemical Inventory:Listed. website: https://chemicaldata.gov.vn/

Philippines Inventory of Chemicals and Chemical Substances (PICCS):Not Listed. website: https://emb.gov.ph/

SECTION 16: Other information

Abbreviations and acronyms

ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
CAS: Chemical Abstracts Service
EC50: Effective Concentration 50%
IATA: International Air Transportation Association
IMDG: International Maritime Dangerous Goods
LC50: Lethal Concentration 50%
LD50: Lethal Dose 50%
RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
STEL: Short term exposure limit
TWA: Time Weighted Average

References

【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple

【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp

【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/

【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en

【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg

【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp

【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm

【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/

【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home

【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/

Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.