138729-47-2 - Safety Data Sheet

Chemical Safety Data Sheet MSDS / SDS

Revision Date:2026-03-20Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

CBnumber: CB1468825
CAS: 138729-47-2
EINECS Number: 202-303-5
Synonyms: Dexzopiclone

Relevant identified uses of the substance or mixture and uses advised against

Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
Uses advised against: none

Company Identification

Company: Chemicalbook
Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
Telephone: 010-86108875

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

Signal wordWarning

Precautionary statements

P264 Wash skin thouroughly after handling.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P201 Obtain special instructions before use.

P202 Do not handle until all safety precautions have been read and understood.

P281 Use personal protective equipment as required.

P308+P313 IF exposed or concerned: Get medical advice/attention.

P405 Store locked up.

P501 Dispose of contents/container to..…

P264 Wash skin thouroughly after handling.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352 IF ON SKIN: wash with plenty of soap and water.

P321 Specific treatment (see … on this label).

P332+P313 IF SKIN irritation occurs: Get medical advice/attention.

P362 Take off contaminated clothing and wash before reuse.

Hazard statements

H361 Suspected of damaging fertility or the unborn child

H315 Causes skin irritation

H335 May cause respiratory irritation

H319 Causes serious eye irritation

SECTION 3: Composition/information on ingredients

Substance

Product name: Eszopiclone
Synonyms: Dexzopiclone
CAS: 138729-47-2
EC number: 202-303-5
MF: C17H17ClN6O3
MW: 388.81

SECTION 4: First aid measures

Description of first aid measures

General information

Symptoms of poisoning may even occur after several hours; therefore medical observation for at least 48 hours after the accident.

After inhalation

Supply fresh air. If required, provide artificial respiration. Keep patient warm. Consult doctor if symptoms persist.
In case of unconsciousness place patient stably in side position for transportation.

After skin contact

Immediately wash with water and soap and rinse thoroughly.

After eye contact

Rinse opened eye for several minutes under running water. If symptoms persist, consult a doctor.

After swallowing

Immediately call a doctor.

Most important symptoms and effects, both acute and delayed

No further relevant information available.

Indication of any immediate medical attention and special treatment needed

No further relevant information available.

SECTION 5: Firefighting measures

FIRE-FIGHTING MEASURES

Fire-fighting measure	Details
Suitable extinguishing agents	Use fire fighting measures that suit the environment. A solid water stream may be inefficient.
Special hazards arising from the substance or mixture	No further relevant information available.
Protective equipment	Mouth respiratory protective device.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Not required.

Environmental precautions

Inform respective authorities in case of seepage into water course or sewage system.
Do not allow to enter sewers/ surface or ground water.

Methods and material for containment and cleaning up

Dispose contaminated material as waste according to section 13.
Ensure adequate ventilation.

Protective Action Criteria for Chemicals

PAC-1

Substance is not listed.

PAC-2

Substance is not listed.

PAC-3

Substance is not listed.

Reference to other sections

See Section 7 for information on safe handling.
See Section 8 for information on personal protection equipment.
See Section 13 for disposal information.

SECTION 7: Handling and storage

Precautions for safe handling

Thorough dedusting.
Ensure good ventilation/exhaustion at the workplace.

Information about protection against explosions and fires

No special measures required.

Conditions for safe storage, including any incompatibilities

Storage

Store in accordance with information listed on the product insert.

Requirements to be met by storerooms and receptacles

No special requirements.

Information about storage in one common storage facility

Not required.

Further information about storage conditions

Keep receptacle tightly sealed.

Specific end use(s)

No further relevant information available.

SECTION 8: Exposure controls/personal protection

Control parameters

Components with limit values that require monitoring at the workplace

Not required.

Additional information

The lists that were valid during the creation were used as basis.

Exposure controls

Appropriate engineering controls

No further data; see section 7.

Personal protective equipment

General protective and hygienic measures

Keep away from foodstuffs, beverages and feed.
Immediately remove all soiled and contaminated clothing.
Wash hands before breaks and at the end of work.
Avoid contact with the eyes and skin.

Breathing equipment

In case of brief exposure or low pollution use respiratory filter device. In case of intensive or longer exposure use respiratory protective device that is independent of circulating air.

Protection of hands

Protective gloves
The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.
Due to missing tests no recommendation to the glove material can be given for the product/ the preparation/ the chemical mixture.
Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation

Material of gloves

The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from manufacturer to manufacturer.

Penetration time of glove material

The exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed.

Eye protection

Tightly sealed goggles

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

Physical StateSolid
ColorAccording to product specification
OdorCharacteristic
Structural FormulaC17H17ClN6O3
Molecular Weight388.8 g/mol
Odor ThresholdNot determined.
Melting point/Melting rangeUndetermined.
Boiling point/Boiling range580.7±50.0 °C(Predicted)
FlammabilityProduct is not flammable.
Explosion limitsLower: Not determined.
Upper: Not determined.
Flash pointNot applicable.
Decomposition temperatureNot determined.
pHNot applicable.
KinematicNot applicable.
SOLUBILITYChloroform (Slightly, Heated), Methanol (Slightly, Heated)
DynamicNot applicable.
Solubility in / Miscibility withChloroform (Slightly, Heated), Methanol (Slightly, Heated)
WaterNot determined.
Partition coefficient (n-octanol/water)Not determined.
Vapor PressureNot applicable.
Density1.54±0.1 g/cm3(Predicted)
Relative Density1.54±0.1 g/cm3(Predicted)
Vapor DensityNot applicable.
Particle characteristicsNot determined.
FormSolid
Ignition temperatureNot determined.
Danger of explosionProduct does not present an explosion hazard.
Evaporation RateNot applicable.

SECTION 10: Stability and reactivity

Reactivity

No further relevant information available.

Chemical stability

Thermal decomposition / conditions to be avoided

No decomposition if used according to specifications.

Possibility of hazardous reactions

No dangerous reactions known.

Conditions to avoid

No further relevant information available.

Incompatible materials

No further relevant information available.

Hazardous decomposition products

No dangerous decomposition products known.

SECTION 11: Toxicological information

Information on toxicological effects

Acute toxicity

LD/LC50 values that are relevant for classification:

Route	Endpoint	Value
Oral	TDLO	0.857 mg/kg (human) 30 mg/kg (rat)
Intraperitoneal	TDLO	5 mg/kg (rat)

Primary irritant effect

on the skin

Irritant to skin and mucous membranes.

on the eye

Irritating effect.

Sensitization

No sensitizing effects known.

Additional toxicological information

Interactive effects

No interactive effects between components are known.

Carcinogenic categories

IARC (International Agency for Research on Cancer)

Substance is not listed.

NTP (National Toxicology Program)

Substance is not listed.

OSHA-Ca (Occupational Safety & Health Administration)

Substance is not listed.

Alternative sources for toxicological information

No non-standard sources for toxicological information where used.

SECTION 12: Ecological information

Results of PBT and vPvB assessment

PBT:

Not applicable.

vPvB:

Not applicable.

Other adverse effects

Remark

Toxic for fish

Additional ecological information

General notes

Water hazard class 2 (Self-assessment) hazardous for water
Do not allow product to reach ground water, water course or sewage system.
Danger to drinking water if even small quantities leak into the ground.
Also poisonous for fish and plankton in water bodies.
Toxic for aquatic organisms

SECTION 13: Disposal considerations

Waste treatment methods

Recommendation

Must not be disposed of together with household garbage. Do not allow product to reach sewage system.

Uncleaned packagings

Recommendation

Disposal must be made according to official regulations.

SECTION 14: Transport information

UN-Number

DOT, IMDG, IATA UN3077

UN proper shipping name

DOT, IATA Environmentally hazardous substance, solid, n.o.s.
(Eszopiclone)
IMDG ENVIRONMENTALLY HAZARDOUS SUBSTANCE,
SOLID, N.O.S. (Eszopiclone)

Transport hazard class(es)

DOT, IMDG

Class: 9 Miscellaneous dangerous substances and articles
Label: 9

IATA

Class: 9 Miscellaneous dangerous substances and articles
Label: 9

Packing group

DOT, IMDG, IATA III

Environmental hazards

Special marking (IATA): Symbol (fish and tree)

Special marking (IATA)

Symbol (fish and tree)

Transport in bulk according to Annex II of MARPOL73/78 and the IBC Code

Not applicable.

Transport/Additional information

DOT:

Quantity limitations

On passenger aircraft/rail: No limit
On cargo aircraft only: No limit

IMDG:

Limited quantities (LQ)

5 kg

Excepted quantities (EQ)

Code: E1
Maximum net quantity per inner packaging: 30 g
Maximum net quantity per outer packaging: 1000 g

IATA:

Remarks

When sold in quantities of less than or equal to 1 mL, or 1 g, with an Excepted Quantity Code of
E1, E2, E4, or E5, this item meets the De Minimis
Quantities exemption, per IATA 2.6.10.
Therefore packaging does not have to be labeled as
Dangerous Goods/Excepted Quantity.

Special precautions for user

Warning: Miscellaneous dangerous substances and

Hazard identification number (Kemler code)

EMS Number

F-A, S-F

Stowage Category

Stowage Code

SW23 When transported in BK3 bulk container, see

UN "Model Regulation"

UN 3077 ENVIRONMENTALLY HAZARDOUS
SUBSTANCE, SOLID, N.O.S. (ESZOPICLONE), 9, III

SECTION 15: Regulatory information

Safety, health and environmental regulations/legislation specific for the substance or mixture

No further relevant information available.

Sara

Section 355 (extremely hazardous substances):	Substance is not listed.
Section 313 (Specific toxic chemical listings):	Substance is not listed.
TSCA (Toxic Substances Control Act):	Substance is not listed.
Hazardous Air Pollutants:	Substance is not listed.
Chemicals known to cause cancer:	Substance is not listed.
Chemicals known to cause reproductive toxicity for females:	Substance is not listed.
Chemicals known to cause reproductive toxicity for males:	Substance is not listed.
Chemicals known to cause developmental toxicity:	Substance is not listed.

Carcinogenic categories

EPA (Environmental Protection Agency):

Substance is not listed.

TLV (Threshold Limit Value)

Substance is not listed.

NIOSH-Ca (National Institute for Occupational Safety and Health)

Substance is not listed.

Chemical safety assessment

A Chemical Safety Assessment has not been carried out.

SECTION 16: Other information

Abbreviations and acronyms

IMDG: International Maritime Code for Dangerous Goods
DOT: US Department of Transportation
IATA: International Air Transport Association
CAS: Chemical Abstracts Service (division of the American Chemical Society)
NFPA: National Fire Protection Association (USA)
HMIS: Hazardous Materials Identification System (USA)
LC50: Lethal concentration, 50 percent
LD50: Lethal dose, 50 percent
PBT: Persistent, Bioaccumulative and Toxic vPvB: very Persistent and very Bioaccumulative
NIOSH: National Institute for Occupational Safety
OSHA: Occupational Safety & Health
TLV: Threshold Limit Value
PEL: Permissible Exposure Limit
REL: Recommended Exposure Limit
Acute toxicity - oral 4: Acute toxicity – Category 4
Skin irritation 2: Skin corrosion/irritation – Category 2
Eye irritation 2A: Serious eye damage/eye irritation – Category 2A
Reproductive toxicity 2: Reproductive toxicity – Category 2
Specific target organ toxicity (single exposure) 3: Specific target organ toxicity (single exposure) – Category 3
Aquatic Chronic 2: Hazardous to the aquatic environment - long-term aquatic hazard – Category 2

Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.