Fenthion

Acute toxicity - Category 4, Oral

Acute toxicity - Category 4, Dermal

Acute toxicity - Category 3, Inhalation

Germ cell mutagenicity, Category 2

Specific target organ toxicity – repeated exposure, Category 1

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

H331 Toxic if inhaled

H341 Suspected of causing genetic defects

H372 Causes damage to organs through prolonged or repeated exposure

H410 Very toxic to aquatic life with long lasting effects

P201 Obtain special instructions before use.

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

P273 Avoid release to the environment.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P311 Call a POISON CENTER or doctor/physician.

P403+P233 Store in a well-ventilated place. Keep container tightly closed.

P501 Dispose of contents/container to..…

P264 Wash ... thoroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

P271 Use only outdoors or in a well-ventilated area.

P203 Obtain, read and follow all safety instructions before use.

P260 Do not breathe dust/fume/gas/mist/vapours/spray.

P273 Avoid release to the environment.

P301+P317 IF SWALLOWED: Get medical help.

P330 Rinse mouth.

P302+P352 IF ON SKIN: Wash with plenty of water/...

P317 Get medical help.

P321 Specific treatment (see ... on this label).

P362+P364 Take off contaminated clothing and wash it before reuse.

P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P316 Get emergency medical help immediately.

P318 IF exposed or concerned, get medical advice.

P319 Get medical help if you feel unwell.

P391 Collect spillage.

P403+P233 Store in a well-ventilated place. Keep container tightly closed.

P405 Store locked up.

P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

no data available

Fresh air, rest. Refer immediately for medical attention.

Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention . Wear protective gloves when administering first aid.

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer immediately for medical attention.

Exposure Routes: inhalation, skin absorption, ingestion, skin and/or eye contact Symptoms: Nausea, vomiting, abdominal cramps, diarrhea, salivation; headache, dizziness, lassitude (weakness, exhaustion); rhinorrhea (discharge of thin mucus), chest tightness; blurred vision, miosis; cardiac irregularities; muscle fasciculation; dyspnea (breathing difficulty) Target Organs: respiratory system, central nervous system, cardiovascular system, plasma cholinesterase (NIOSH, 2016)

1. insure that a clear airway exists by aspiration of secretions if necessary. admin oxygen by mechanically assisted pulmonary ventilation if respiration is depressed. improve tissue oxygenation as much as possible before admin atropine to minimize risk of ventricular fibrillation. in severe poisonings, it may be necessary to support pulmonary ventilation mechanically for several days. 2. admin atropine sulfate iv, or im if iv injection is not possible. ... in moderately severe poisoning: adult dosage and children over 12 yr: 0.4-2.0 mg repeated every 15 min until atropinization is achieved. maintain atropinization with repeated dosage of 0.02-0.05 mg/kg body weight. organophosphate pesticides

Dry chemicals, carbon dioxide for small fires. Water spray, foam for large fires. Malathion

This compound is probably combustible. (NTP, 1992)

Use water spray, foam, powder, carbon dioxide.

Personal protection: chemical protection suit, protective gloves and filter respirator for organic gases and particulates adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in dry sand or inert absorbent. Then store and dispose of according to local regulations.

Personal protection: chemical protection suit, protective gloves and filter respirator for organic gases and particulates adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in dry sand or inert absorbent. Then store and dispose of according to local regulations.

1. ventilate area of spill or leak. 2. collect for reclamation or absorb in vermiculite, dry sand, earth, or a similar material. malathion

NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Separated from strong oxidants and food and feedstuffs. Well closed. Keep in a well-ventilated room. Provision to contain effluent from fire extinguishing. Store in an area without drain or sewer access.Store in original container, preferably in a locked area, away from children, food, feed.

TLV: 0.05 mg/m3, as TWA; (skin); A4 (not classifiable as a human carcinogen); BEI issued.MAK: (inhalable fraction): 0.2 mg/m3; peak limitation category: II(2); skin absorption (H)

no data available

Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.

Wear face shield or eye protection in combination with breathing protection.

Protective gloves. Protective clothing.

Use ventilation, local exhaust or breathing protection.

no data available

Decomposes on heating. This produces toxic fumes including phosphorus oxides and sulfur oxides. Reacts with oxidants.

Stable to light

FENTHION may react with strong reducing agents such as hydrides to generate highly toxic and flammable phosphine gas. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

no data available

incompatible with /insecticides and fungicides/ which are highly alkaline.

When heated to decomposition it emits very toxic fumes of /phosphorus oxides and sulfur oxides/.

no data available

no data available

no data available

no data available

Cancer Classification: Group E Evidence of Non-carcinogenicity for Humans

no data available

Cholinesterase inhibition. The substance may cause effects on the nervous system. This may result in convulsions and respiratory failure. The effects may be delayed. Medical observation is indicated.

Cholinesterase inhibition. Cumulative effects are possible. See Acute Hazards/Symptoms.

A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20°C; on spraying or dispersing, however, much faster.

The effects of some potential chemical, photochemical, biological and environmental conditions upon the degradation of fenthion in laboratory and field experiments were investigated. The effects of biological activity on the degradation of fenthion were examined with mangrove swamp water in a dark bottle. Photolytic degradation was observed with mangrove water that was sterilized by the addition of mercuric chloride to 40 ppm and exposed to natural sunlight for the field study. Different natural waters (ocean, inlet, estuarine, mangrove swamp, freshwater lake, and canal) were collected and incubated in the pond for studying the fenthion disappearance rate in different types of water bodies. The stability of fenthion under acidic and alkaline conditions was observed for hydrolytic degradation. A comparison of the biological degradation by aquatic microorganisms against that of chemical degradation by pH adjustment was also investigated. The results show that fenthion remains relatively stable under acidic to neutral conditions. Under alkaline conditions fenthion still remains stable up to pH 11. Higher salinity resulted in a shorter half-life. Fenthion was found to be susceptible to biological degradation by anaerobic or non-photolytic organisms. In natural waters, the degradation of fenthion was related to the biological activity of each water sample. Mangrove water exhibited the lowest half-life (2.9 days) while the ocean water showed the longest half-life (21.1 days).

Using a flow-through system and up to 11 days of exposure, a mean BCF of 16,600 (extractable lipid basis) was measured in guppies (Poecilia reticulata)(1). Based upon a measured Log Kow of 4.09(2) and a water solubility of 7.5 mg/l at 20 deg C(3), the BCF of fenthion can be estimated to be 760 and 200, respectively, from regression derived equations(4,SRC). These measured and estimated BCF values suggest that bioconcentration in aquatic organisms may have some environmental importance(SRC). A fenthion BCF of 62 was measured in tadpoles after a 96 hr exposure period in a flow-through system(5).

Based upon a measured log Kow of 4.09(1) and a water solubility of 7.5 mg/l at 20 deg C(2), the Koc of fenthion can be estimated to be 4000 and 1400, respectively, from regression derived equations(3,SRC). The US Dept Agric's Pesticide Properties Database lists a Koc value of 1500 for fenthion(4). According to a suggested classification scheme(5), these estimated Koc values suggest that fenthion is only slightly mobile in soil(SRC).

no data available

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

ADR/RID: UN2784 (For reference only, please check.)

IMDG: UN2784 (For reference only, please check.)

IATA: UN2784 (For reference only, please check.)

ADR/RID: ORGANOPHOSPHORUS PESTICIDE, LIQUID, FLAMMABLE, TOXIC, flash point less than 23 °C (For reference only, please check.)

IMDG: ORGANOPHOSPHORUS PESTICIDE, LIQUID, FLAMMABLE, TOXIC, flash point less than 23 °C (For reference only, please check.)

IATA: ORGANOPHOSPHORUS PESTICIDE, LIQUID, FLAMMABLE, TOXIC, flash point less than 23 °C (For reference only, please check.)

ADR/RID: 3 (For reference only, please check.)

IMDG: 3 (For reference only, please check.)

IATA: 3 (For reference only, please check.)

ADR/RID: I (For reference only, please check.)

IMDG: I (For reference only, please check.)

IATA: I (For reference only, please check.)

ADR/RID: Yes

IMDG: Yes

IATA: Yes

no data available

no data available

The technical grade (95-98% pure) is a yellow to brown oil with a weak garlic-like odour.Carrier solvents used in commercial formulations may change physical and toxicological properties.Do NOT take working clothes home.Depending on the degree of exposure, periodic medical examination is suggested.Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions must be available.