Hexachlorophene

Acute toxicity - Category 3, Oral

Acute toxicity - Category 3, Dermal

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

H225 Highly Flammable liquid and vapour

H370 Causes damage to organs

H410 Very toxic to aquatic life with long lasting effects

H411 Toxic to aquatic life with long lasting effects

P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P260 Do not breathe dust/fume/gas/mist/vapours/spray.

P273 Avoid release to the environment.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P311 Call a POISON CENTER or doctor/physician.

P312 Call a POISON CENTER or doctor/physician if you feel unwell.

P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P501 Dispose of contents/container to..…

P264 Wash ... thoroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

P273 Avoid release to the environment.

P301+P316 IF SWALLOWED: Get emergency medical help immediately.

P321 Specific treatment (see ... on this label).

P330 Rinse mouth.

P302+P352 IF ON SKIN: Wash with plenty of water/...

P316 Get emergency medical help immediately.

P361+P364 Take off immediately all contaminated clothing and wash it before reuse.

P391 Collect spillage.

P405 Store locked up.

P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

no data available

Fresh air, rest.

Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .

Rinse with plenty of water (remove contact lenses if easily possible).

Rinse mouth. Rest. Give a slurry of activated charcoal in water to drink. Refer immediately for medical attention.

Inhalation of dust is poisonous; irritating to mucous membranes. Eye and skin irritant. Poisonous if swallowed. Symptoms following ingestion include anorexia, nausea, vomiting, abdominal cramps, and diarrhea. Dehydration may be severe and may be associated with shock. (USCG, 1999)

Other therapies. Though this compound is quite toxic systemically and enhanced clearance methods would appear beneficial, there is no evidence to support the efficacy of hemodialysis, peritoneal dialysis, hemoperfusion, or exchange transfusion.

If material on fire or involved in fire: Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.) Use water in flooding quantities as fog. Use foam, dry chemical or carbon dioxide. Keep run-off waste out of sewers and water sources.

Special Hazards of Combustion Products: Contain toxic and irritating chloride fumes. Behavior in Fire: Decomposes to produce toxic and irritating gases. (USCG, 1999)

Use water spray, powder, foam, carbon dioxide.

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Do NOT let this chemical enter the environment. Sweep spilled substance into covered sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations.

Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.

NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Separated from food and feedstuffs. Store in an area without drain or sewer access. Provision to contain effluent from fire extinguishing.Store at room temperature up to 25 deg C (77 deg F).

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Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.

Wear face shield.

Protective gloves. Protective clothing.

Use local exhaust or breathing protection.

no data available

Decomposes on heating and on burning. This produces toxic and irritating fumes including hydrogen chloride. Reacts with strong oxidants.

no data available

HEXACHLOROPHENE is incompatible with strong oxidizers. It forms salts with alkalis and alkaline earths. (NTP, 1992)

no data available

Oxidizers.

When heated to decomposition, it emits highly toxic fumes of ... /hydrogen chloride/.

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Classification of carcinogenicity: 1) evidence in humans: no data; 2) evidence in animals: inadequate. Overall summary evaluation of carcinogenic risk to humans is Group 3: The agent is not classifiable as to its carcinogenicity to humans. From table

no data available

The substance may cause effects on the nervous system and optic nerve. This may result in cardiac disorders, respiratory failure and blindness. The effects may be delayed up to 48 hours. Medical observation is indicated.

Repeated or prolonged contact with skin may cause dermatitis. Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the nervous system and optic nerve. This may result in tissue lesions and blindness. May cause toxicity to human reproduction or development.

A nuisance-causing concentration of airborne particles can be reached quickly when dispersed.

AEROBIC: Hexachlorophene, present at 100 mg/L, reached 0% of its theoretical BOD in 4 weeks using an activated sludge inoculum at 30 mg/L in the Japanese MITI test(1). Radio-labeled C14-hexachlorophene was not biodegraded in surface water from the Skidaway River, GA(2). In sediments from Skidaway River, radio-labeled C14-hexachlorophene was degraded with a half-life of 290 days(2).

The BCF of hexachlorophene in carp (Cyprinus carpio), exposed for 8 weeks to 2 and 0.2 ug/L were 87-148 and 82-153, respectively(1). BCFs for hexachlorophene in mosquito fish (Gambusia affinis) and snails (Physa sp) are 278 and 970, respectively(2). According to a classification scheme(3), these BCFs suggest the potential for bioconcentration in aquatic organisms is moderate to high(SRC).

The Koc of hexachlorophene has been reported as 91,000(1). According to a classification scheme(2), this Koc value suggests that hexachlorophene is expected to be immobile in soil. The pKa of hexachlorophene is 4.95(3), indicating that this compound will partially exist in anion form in the environment and anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(4). A study of the mobility in Hagerstown silty clay loam soil TLC (thin layer chormatography) plates using 10 soil fungi and an alga (range of Rf values, 0.01-0.04, avg 0.01) indicated very little movement on the soil TLC plates(5). A monitoring study identified hexachlorophene in humic acid fractions of two sediment samples taken at least eight years after the FDA ban on the over-the-counter sale of cosmetics and drugs containing more than 0.1% hexachlorophene(6). These data indicate that hexachlorophene was strongly associated with organic matter which may have been as a result of covalent binding of the ionizable compound(5-6).

no data available

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

ADR/RID: UN2875 (For reference only, please check.)

IMDG: UN2875 (For reference only, please check.)

IATA: UN2875 (For reference only, please check.)

ADR/RID: HEXACHLOROPHENE (For reference only, please check.)

IMDG: HEXACHLOROPHENE (For reference only, please check.)

IATA: HEXACHLOROPHENE (For reference only, please check.)

ADR/RID: 6.1 (For reference only, please check.)

IMDG: 6.1 (For reference only, please check.)

IATA: 6.1 (For reference only, please check.)

ADR/RID: III (For reference only, please check.)

IMDG: III (For reference only, please check.)

IATA: III (For reference only, please check.)

ADR/RID: Yes

IMDG: Yes

IATA: Yes

no data available

no data available