Chemical Safety Data Sheet MSDS / SDS

Methanesulfonic acid

Revision Date:2022-11-12Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

  • Product name: Methanesulfonic acid
  • CBnumber: CB3433704
  • CAS: 75-75-2
  • EINECS Number: 200-898-6
  • Synonyms: METHANESULFONIC ACID,MsOH

Relevant identified uses of the substance or mixture and uses advised against

  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none

Company Identification

  • Company: Chemicalbook
  • Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
  • Telephone: 400-158-6606

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

  • Symbol(GHS)
  • Signal wordDanger
Precautionary statements
P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.
Hazard statements
H290 May be corrosive to metals
H302 Harmful if swallowed
H314 Causes severe skin burns and eye damage
H318 Causes serious eye damage
H335 May cause respiratory irritation

SECTION 3: Composition/information on ingredients

Substance

  • Product name: Methanesulfonic acid
  • Synonyms: METHANESULFONIC ACID,MsOH
  • CAS: 75-75-2
  • EC number: 200-898-6
  • MF: CH4O3S
  • MW: 96.11

SECTION 4: First aid measures

Description of first aid measures

General advice
First aiders need to protect themselves. Show this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. Call in physician.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Call a physician immediately.
In case of eye contact
After eye contact: rinse out with plenty of water. Immediately call in ophthalmologist. Remove contact lenses.
If swallowed
After swallowing: make victim drink water (two glasses at most), avoid vomiting (risk of perforation). Call a physician immediately. Do not attempt to neutralise.

Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11

Indication of any immediate medical attention and special treatment needed

No data available

SECTION 5: Firefighting measures

Extinguishing media

Suitable extinguishing media
Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
Foam Water

Special hazards arising from the substance or mixture

Carbon oxides Sulfur oxides Combustible.

Vapors are heavier than air and may spread along floors. Forms explosive mixtures with air on intense heating.

Development of hazardous combustion gases or vapours possible in the event of fire.

Advice for firefighters

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

Further information

Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.

For personal protection see section 8.

Environmental precautions

Do not let product enter drains.

Methods and materials for containment and cleaning up

Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up with liquid-absorbent and neutralising material (e.g. Chemizorb? H ? , Merck Art. No. 101595). Dispose of properly. Clean up affected area.

Reference to other sections

For disposal see section 13.

SECTION 7: Handling and storage

Precautions for safe handling

For precautions see section 2.2.

Conditions for safe storage, including any incompatibilities

Storage conditions

Tightly closed. Heat sensitive.

Specific end use(s)

Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

control parameter

Hazard composition and occupational exposure limits
Does not contain substances with occupational exposure limits.

Exposure controls

Personal protective equipment
Eye/face protection

Use equipment for eye protection tested and approved under appropriate

government standards such as NIOSH (US) or EN 166(EU). Tightly fitting safety goggles

Skin protection

This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Full contact

Material: Chloroprene

Minimum layer thickness: 0,65 mm Break through time: 480 min Material tested:KCL 720 Camapren?

This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Splash contact Material: Nitrile rubber

Minimum layer thickness: 0,4 mm Break through time: 60 min

Material tested:Camatril? (KCL 730 / Aldrich Z677442, Size M)

Body Protection

Acid-resistant protective clothing

Respiratory protection

Recommended Filter type: Filter type B

The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.

These measures have to be properly documented.

Control of environmental exposure

Do not let product enter drains.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

  • AppearanceForm: liquid Color: light yellow
  • Odourcharacteristic
  • Odour ThresholdNo data available
  • pH< 1 at 20 °C
  • Melting point/freezing pointMelting point/range: 17 - 19 °C - lit.
  • Initial boiling point and boiling range167 °C at 13 hPa - lit.
  • Flash point189 °C - closed cup - DIN 51755 Part 1
  • Evaporation rateNo data available
  • Flammability (solid, gas)No data available
  • Upper/lower flammability or explosive limits Upper explosion limit: 24,3 %(V) Lower explosion limit: 11,4 %(V)
  • Vapour pressure 0,112 hPa at 80 °C - OECD Test Guideline 104
  • Vapour density 3,32 - (Air = 1.0)
  • Relative density1.48 (18/4℃)
  • Water solubilityca.1.000 g/l at 20 °C - completely miscible
  • Partition coefficient: n-octanol/waterlog Pow: -2,38 at 20 °C - - Bioaccumulation is not expected.
  • Autoignition temperature535 °C at 1.010 hPa - DIN 51794
  • Decomposition temperature No data available
  • ViscosityViscosity, kinematic: 7,86 mm2/s at 25 °C Viscosity, dynamic: 11,6 mPa.s at 25 °C
  • Explosive propertiesNo data available
  • Oxidizing propertiesNo data available
  • λmaxλ: 240-320 nm Amax: <0.4

Other safety information

Dissociation constant -1,54 at 25 °C


Relative vapor density

3,32 - (Air = 1.0)

SECTION 10: Stability and reactivity

Reactivity

Forms explosive mixtures with air on intense heating.

A range from approx. 15 Kelvin below the flash point is to be rated as critical.

Chemical stability

The product is chemically stable under standard ambient conditions (room temperature) .

Possibility of hazardous reactions

Violent reactions possible with:

strong alkalis Oxidizing agents strong reducing agents Amines

Hydrogen fluoride acids

strong alkalis Bases

Risk of explosion/exothermic reaction with: Water

Hydrogen fluoride


Conditions to avoid

Heat.

Strong heating.

Incompatible materials

various metals, i.a., Iron, Copper, brass, Mild steel

Hazardous decomposition products

In the event of fire: see section 5

SECTION 11: Toxicological information

Information on toxicological effects

Acute toxicity
LD50 Oral - Rat - male and female - 648,7 mg/kg
(OECD Test Guideline 401)
LD50 Dermal - Rabbit - male and female - 2.000 mg/kg (OECD Test Guideline 402)
Skin corrosion/irritation
Serious eye damage/eye irritation
Eyes - Rabbit
Result: Causes burns.
(OECD Test Guideline 405)
Respiratory or skin sensitization
Buehler Test - Guinea pig Result: negative
(OECD Test Guideline 406)
Germ cell mutagenicity
Test Type: Ames test
Test system: Salmonella typhimurium
Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 471
Result: negative
Test Type: In vitro mammalian cell gene mutation test Test system: Chinese hamster ovary cells
Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 476
Result: negative
Test Type: In vivo micronucleus test Species: Mouse
Cell type: Bone marrow Application Route: Oral
Method: OECD Test Guideline 474 Result: negative
Carcinogenicity
No data available
Reproductive toxicity
No data available
Specific target organ toxicity - single exposure
May cause respiratory irritation.
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available
Toxicity
LD50 orally in Rabbit: 649 mg/kg LD50 dermal Rabbit 200 - 2000 mg/kg

SECTION 12: Ecological information

Toxicity

Toxicity to fish
static test LC50 - Oncorhynchus mykiss (rainbow trout) - 73 mg/l - 96 h

(OECD Test Guideline 203)

Toxicity to daphnia and other aquatic invertebrates

static test EC50 - Daphnia magna (Water flea) - 70 mg/l - 48 h (OECD Test Guideline 202)

Toxicity to algae
static test ErC50 - Pseudokirchneriella subcapitata (green algae) - 12

- 24 mg/l - 72 h

(OECD Test Guideline 201)

Toxicity to bacteria
static test EC50 - activated sludge - > 1.000 mg/l - 0,5 h (OECD Test Guideline 209)

Persistence and degradability

Biodegradability aerobic Chemical oxygen demand - Exposure time 28 d Result: 90 - 100 % - Readily biodegradable.

(OECD Test Guideline 301A)

Bioaccumulative potential

No data available

Mobility in soil

No data available

Results of PBT and vPvB assessment

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

Other adverse effects

No data available

SECTION 13: Disposal considerations

Waste treatment methods

Product

See www.retrologistik.com for processes regarding the return of chemicals and

containers, or contact us there if you have further questions.

SECTION 14: Transport information

UN number

ADR/RID: 3265 IMDG: 3265 IATA: 3265

UN proper shipping name

ADR/RID: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S. (Methanesulfonic acid)

IMDG: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S. (Methanesulfonic acid)

IATA: Corrosive liquid, acidic, organic, n.o.s. (Methanesulfonic acid)

Transport hazard class(es)

ADR/RID: 8 IMDG: 8 IATA: 8

Packaging group

ADR/RID: II IMDG: II IATA: II

Environmental hazards

ADR/RID: no IMDG Marine pollutant: no IATA: no

Special precautions for user

No data available

SECTION 15: Regulatory information

Safety, health and environmental regulations/legislation specific for the substance or mixture

Regulations on the Safety Management of Hazardous Chemicals
China Catalog of Hazardous chemicals 2015:Listed. website: https://www.mem.gov.cn/
Measures for Environmental Management of New Chemical Substances
Vietnam National Chemical Inventory:Listed. website: https://chemicaldata.gov.vn/
United States Toxic Substances Control Act (TSCA) Inventory:Listed. website: https://www.epa.gov/
Philippines Inventory of Chemicals and Chemical Substances (PICCS):Listed. website: https://emb.gov.ph/
New Zealand Inventory of Chemicals (NZIoC):Listed. website: https://www.epa.govt.nz/
Korea Existing Chemicals List (KECL):Listed. website: http://ncis.nier.go.kr
European Inventory of Existing Commercial Chemical Substances (EINECS):Listed. website: https://echa.europa.eu/
EC Inventory:Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC):Listed. website: https://www.mee.gov.cn/

SECTION 16: Other information

Abbreviations and acronyms

  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • CAS: Chemical Abstracts Service
  • EC50: Effective Concentration 50%
  • IATA: International Air Transportation Association
  • IMDG: International Maritime Dangerous Goods
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • STEL: Short term exposure limit
  • TWA: Time Weighted Average

References

【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple

【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp

【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/

【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en

【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg

【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp

【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm

【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/

【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home

【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/

Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.

Recommended Products
(1R)-(-)-10-Camphorsulfonic acid SDS 2-PYRIDYLHYDROXYMETHANESULFONIC ACID SDS Methanesulfonic acid SDS Folic acid SDS D-3-Bromocamphor-8-sulfonic acid ammonium salt SDS 2-CHLOROETHYL METHANESULFONATE SDS Trifluoromethanesulfonic anhydride SDS Glycine SDS Methyl p-toluenesulfonate SDS Citric acid SDS