Chemical Safety Data Sheet MSDS / SDS
METHYLBROMOCHLOROACETATE
Revision Date:2026-03-21Revision Number:1
Product identifier
- Product name: METHYLBROMOCHLOROACETATE
- CBnumber: CB9307711
- CAS: 20428-74-4
- EINECS Number: 690-379-4
- Synonyms: BROMOCHLOROACETIC ACID METHYL ESTER;Methyl bromochloroacetate solution
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
Hazard statements
H315 Causes skin irritation
H225 Highly Flammable liquid and vapour
Substance
- Product name: METHYLBROMOCHLOROACETATE
- Synonyms: BROMOCHLOROACETIC ACID METHYL ESTER;Methyl bromochloroacetate solution
- CAS: 20428-74-4
- EC number: 690-379-4
- MF: C3H4BrClO2
- MW: 187.42
First Aid Measures
General adviceImmediate medical attention is required. In case of accident or unwellness, seek medical advice immediately (show directions for use or safety data sheet if possible). If symptoms persist, call a physician.
Eye contact
Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. If symptoms persist, call a physician. Immediately flush with plenty of water. After initial flushing, remove any contact lenses and continue flushing for at least 15 minutes. Keep eye wide open while rinsing.
Skin Contact
Wash off immediately with plenty of water. Wash contaminated clothing before reuse. If skin irritation persists, call a physician. Immediate medical attention is not required. Wash off immediately with soap and plenty of water while removing all contaminated clothes and shoes.
Inhalation
Remove to fresh air If symptoms persist, call a physician Immediate medical attention is not required Move to fresh air in case of accidental inhalation of vapors
Ingestion
Immediate medical attention is not required. Rinse mouth. Drink plenty of water. Do NOT induce vomiting. Clean mouth with water and drink afterwards plenty of water. Never give anything by mouth to an unconscious person. Call a physician.
Self-protection of the first aider
Remove all sources of ignition. Use personal protective equipment as required.
Most important symptoms and effects, both acute and delayed
SymptomsNo information available.
Indication of any immediate medical attention and special treatment needed
Note to physiciansTreat symptomatically.
Suitable Extinguishing Media
Suitable Extinguishing MediaUse extinguishing measures that are appropriate to local circumstances and the surrounding environment.
Unsuitable Extinguishing Media
None.
Specific hazards arising from the chemical
Specific hazards arising from the chemicalThermal decomposition can lead to release of toxic/corrosive gases and vapors.
Hazardous combustion products
Carbon oxides. Phosgene.
Explosion data
Sensitivity to Mechanical ImpactNo information available.
Sensitivity to Static Discharge
No information available.
Protective equipment and precautions for firefighters
Protective equipment and precautions for firefightersAs in any fire, wear self contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear.
Personal precautions, protective equipment and emergency procedures
Personal precautionsRemove all sources of ignition. Evacuate personnel to safe areas. Ensure adequate ventilation, especially in confined areas. Use personal protective equipment as required.
Keep people away from and upwind of spill/leak.
Keep people away from and upwind of spill/leak.
Environmental precautions
Environmental precautionsPrevent further leakage or spillage if safe to do so. Prevent product from entering drains. Do not flush into surface water or sanitary sewer system. See Section 12 for additional
Ecological Information.
Ecological Information.
Methods and material for containment and cleaning up
Methods for containmentPrevent further leakage or spillage if safe to do so.
Methods for cleaning up
Pick up and transfer to properly labeled containers. Dam up. Soak up with inert absorbent material (e.g. sand, silica gel, acid binder, universal binder, sawdust). Soak up with inert absorbent material.
Precautions for safe handling
Advice on safe handlingEnsure adequate ventilation, especially in confined areas. Keep away from heat, sparks, flame and other sources of ignition (i.e., pilot lights, electric motors and static electricity).
Take precautionary measures against static discharges. Use spark-proof tools and explosion-proof equipment. All equipment used when handling the product must be grounded. Use with local exhaust ventilation. Use personal protective equipment as required. Do not breathe dust/fume/gas/mist/vapors/spray. Thermal decomposition can lead to release of toxic/corrosive gases and vapors.
Take precautionary measures against static discharges. Use spark-proof tools and explosion-proof equipment. All equipment used when handling the product must be grounded. Use with local exhaust ventilation. Use personal protective equipment as required. Do not breathe dust/fume/gas/mist/vapors/spray. Thermal decomposition can lead to release of toxic/corrosive gases and vapors.
Conditions for safe storage, including any incompatibilities
Storage ConditionsKeep tightly closed in a dry and cool place. Keep in properly labeled containers. Keep containers tightly closed in a cool, well-ventilated place. Store at 4 °C.
Incompatible materials
None known based on information supplied.
Control parameters
Exposure Guidelines.
| Chemical Name | ACGIH TLV | OSHA PEL | NIOSH IDLH |
|---|---|---|---|
| tert-Butyl methyl ether 1634-04-4 | TWA: 50 ppm | - | - |
Appropriate engineering controls
Engineering ControlsShowers
Eyewash stations
Ventilation systems
Eyewash stations
Ventilation systems
Individual protection measures, such as personal protective equipment
Eye/face protectionTight sealing safety goggles. Face protection shield.
Skin and Body Protection
Wear protective gloves and protective clothing.
Respiratory protection
If exposure limits are exceeded or irritation is experienced, NIOSH/MSHA approved respiratory protection should be worn. Positive-pressure supplied air respirators may be required for high airborne contaminant concentrations. Respiratory protection must be provided in accordance with current local regulations.
General Hygiene Considerations
When using do not eat, drink or smoke. Regular cleaning of equipment, work area and clothing is recommended.
Information on basic physicochemical properties
- Physical Stateliquid
- AppearanceNo information available
- OdorNo information available
- pHNo information available
- Melting point/freezing point-108.59 °C
- Boiling point55 °C
- Flash point-32.99 °C CC (closed cup)
- Density0.74 g/cm3
- Evaporation rateNo information available
- Upper flammability limits15.1%
- Lower flammability limit1.6%
- Vapor pressureNo information available
- Vapor densityNo information available
- Specific gravityNo information available
- Water solubilityNo information available
- Solubility in other solventsNo information available
- Partition coefficient1.06
- Autoignition temperature374 °C
- Decomposition temperatureNo information available
- Kinematic viscosityNo information available
- Explosive propertiesNo information available
- Oxidizing propertiesNo information available
Reactivity
Not applicable
Chemical stability
Stable under recommended storage conditions.
Possibility of Hazardous Reactions
None under normal processing.
Hazardous polymerization
No information available.
Conditions to avoid
Heat, flames and sparks.
Incompatible materials
Strong oxidizing agents.
Hazardous Decomposition Products
Carbon oxides. Phosgene.
Information on likely routes of exposure
InhalationClassified based on available data. For more details, see section 2.
Eye contact
Classified based on available data. For more details, see section 2.
Skin Contact
Classified based on available data. For more details, see section 2.
Ingestion
Classified based on available data. For more details, see section 2.
Information on toxicological effects
SymptomsClassified based on available data. For more details, see section 2.
Delayed and immediate effects as well as chronic effects from short and long-term exposure
Chronic ToxicityAvoid repeated exposure. Carcinogenicity The table below indicates whether each agency has listed any ingredient as a carcinogen.
Chemical Name ACGIH IARC NTP OSHA
tert-Butyl methyl ether A3 Group3 - - 1634-04-4
Numerical measures of toxicity - Product Information
Unknown acute toxicityClassified based on available data. For more details, see section 2
The following values are calculated based on chapter 3.1 of the GHS document
ATEmix (oral)
The following values are calculated based on chapter 3.1 of the GHS document
2966 mg/kg
ATEmix (dermal)
10010 mg/kg
ATEmix (inhalation-vapor)
23600 mg/l
Ecotoxicity
| Chemical Name | Algae/aquatic plants | Fish | Toxicity to Microorganisms | Crustacea |
|---|---|---|---|---|
| tert-Butyl methyl ether 1634-04-4 | 184: 96 h Pseudokirchneriella subcapitata mg/L EC50 800: 72 h Desmodesmus subspicatus mg/L EC50 | 672: 96 h Pimephales promelas mg/L LC50 flow-through 887: 96 h Oncorhynchus mykiss mg/L LC50 flow-through 100: 96 h Brachydanio rerio mg/L LC50 semi-static 929: 96 h Pimephales promelas mg/L LC50 static | - | 542: 48 h Daphnia magna mg/L EC50 |
tert-Butyl methyl ether 184: 96 h
672: 96 h Pimephales - 542: 48 h Daphnia magna
LC50 semi
static 929: 96 h
Pimephales promelas mg/L
LC50 static 0.1% of the mixture consists of components(s) of unknown hazards to the aquatic environment.
Persistence and degradability No information available. Bioaccumulation No information available. Mobility No information available.
tert-Butyl methyl ether
1.06 1634-04-4
Disposal of wastes
Disposal should be in accordance with applicable regional, national and local laws and regulations.
Contaminated packaging
Do not reuse container.
Other Information
Waste codes should be assigned by the user based on the application for which the product was used.
DOT
UN/ID noUN2398
Hazard Class
3
Packing Group
II
Proper shipping name
Methyl tert-butyl ether
Description
UN2398, Methyl tert-butyl ether, 3, II
Emergency Response Guide Number
127
IMDG
UN/ID noUN2398
Hazard Class
3
Packing Group
II
Proper shipping name
Methyl tert-butyl ether
Description
UN2398, Methyl tert-butyl ether, 3, II, (-32.99°C c.c.)
EmS-No
F-E, S-D
IATA
UN/ID noUN2398
Hazard Class
3
Packing Group
II
Proper shipping name
Methyl tert-butyl ether
Description
UN2398, Methyl tert-butyl ether, 3, II
International Inventories
All of the components in the product are on the following Inventory lists
X - Listed
TSCA - United States Toxic Substances Control Act Section 8(b) Inventory
DSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances List
EINECS/ELINCS - European Inventory of Existing Chemical Substances/European List of Notified Chemical Substances
ENCS - Japan Existing and New Chemical Substances
IECSC - China Inventory of Existing Chemical Substances
KECL - Korean Existing and Evaluated Chemical Substances
PICCS - Philippines Inventory of Chemicals and Chemical Substances
X - Listed
TSCA - United States Toxic Substances Control Act Section 8(b) Inventory
DSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances List
EINECS/ELINCS - European Inventory of Existing Chemical Substances/European List of Notified Chemical Substances
ENCS - Japan Existing and New Chemical Substances
IECSC - China Inventory of Existing Chemical Substances
KECL - Korean Existing and Evaluated Chemical Substances
PICCS - Philippines Inventory of Chemicals and Chemical Substances
| Chemical name | TSCA | DSL | NDSL | EINECS | ELINCS | ENCS | IECSC | KECL | PICCS | AICS |
|---|---|---|---|---|---|---|---|---|---|---|
| tert-Butyl methyl ether | X | X | - | X | - | X | X | X | X | X |
US Federal Regulations
SARA 313
Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA). This product does not contain any chemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372.
SARA 311/312 Hazard Categories
Acute health hazardYes
Chronic Health Hazard
No
Fire hazard
Yes
Sudden release of pressure hazard
No
Reactive hazard
No
CWA (Clean Water Act)
This product does not contain any substances regulated as pollutants pursuant to the Clean Water Act (40 CFR 122.21 and 40
CFR 122.42).
CFR 122.42).
US State Regulations
California Proposition 65
This product does not contain any Proposition 65 chemicals.
U.S. State Right-to-Know Regulations
| Chemical Name | New Jersey | Massachusetts | Pennsylvania |
|---|---|---|---|
| tert-Butyl methyl ether 1634-04-4 | X | X | X |
Abbreviations and acronyms
CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.