Chemical Safety Data Sheet MSDS / SDS

N-NITROSODIMETHYLAMINE

Revision Date:2026-03-20Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

Product name: N-NITROSODIMETHYLAMINE
CBnumber: CB8364791
CAS: 62-75-9
EINECS Number: 200-549-8
Synonyms: NDMA;N,N-dimethylnitrous amide

Relevant identified uses of the substance or mixture and uses advised against

Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
Uses advised against: none

Company Identification

Company: Chemicalbook
Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
Telephone: 010-86108875

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

Symbol(GHS)

Signal wordDanger

Precautionary statements

P264 Wash skin thouroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P321 Specific treatment (see … on this label).

P330 Rinse mouth.

P405 Store locked up.

P501 Dispose of contents/container to..…

P260 Do not breathe dust/fume/gas/mist/vapours/spray.

P271 Use only outdoors or in a well-ventilated area.

P284 Wear respiratory protection.

P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P310 Immediately call a POISON CENTER or doctor/physician.

P320 Specific treatment is urgent (see … on this label).

P403+P233 Store in a well-ventilated place. Keep container tightly closed.

P405 Store locked up.

P501 Dispose of contents/container to..…

P260 Do not breathe dust/fume/gas/mist/vapours/spray.

P264 Wash skin thouroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P314 Get medical advice/attention if you feel unwell.

P501 Dispose of contents/container to..…

Hazard statements

H301 Toxic if swalloed

H330 Fatal if inhaled

H350 May cause cancer

H372 Causes damage to organs through prolonged or repeated exposure

H411 Toxic to aquatic life with long lasting effects

SECTION 3: Composition/information on ingredients

Substance

Product name: N-NITROSODIMETHYLAMINE
Synonyms: NDMA;N,N-dimethylnitrous amide
CAS: 62-75-9
EC number: 200-549-8
MF: C2H6N2O
MW: 74.08

SECTION 4: First aid measures

If inhaled

Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER or doctor/ physician.

In case of skin contact

Take off all contaminated clothing immediately. If on skin, rinse well with water. Call a POISON CENTER or doctor/ physician.

In case of eye contact

Rinse with plenty of water. If easy to do, remove contact lens, if worn. Call a POISON CENTER or doctor/ physician.

If swallowed

Immediately call a POISON CENTER or doctor/ physician. Rinse mouth.

Most important symptoms and effects, both acute and delayed

None known.

SECTION 5: Firefighting measures

Suitable extinguishing media

Dry powder, Foam, Water spray, Carbon dioxide (CO2)

Specific hazards during fire fighting

No information available.

Specific extinguishing methods

Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. Immediately evacuate personnel to safe areas. Cool closed containers exposed to fire with water spray. Remove undamaged containers from fire area if it is safe to do so.

Special protective equipment for fire-fighters

Use personal protective equipment.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Wear suitable protective equipment. Keep people away from and upwind of spill/leak. Ensure adequate ventilation. Entry to non-involved personnel should be controlled around the leakage area by roping off, etc.

Environmental precautions

Should not be released into the environment.

Methods and materials for containment and cleaning up

Collect as much of the spill as possible with a suitable absorbent material.

SECTION 7: Handling and storage

Handling

Technical measures

Prevent generation of vapor or mist. Take precautionary measures against static discharge. Use explosion-proof equipment.

Local/Total ventilation

Ensure adequate ventilation. Handle product only in closed system or provide appropriate exhaust ventilation at machinery. Use a local exhaust ventilation.

Advice on safe handling

Avoid contact with skin, eyes and clothing. Wear personal protective equipment. Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. Do not subject to grinding, shock or friction. Wash hands and face thoroughly after handling.

Avoidance of contact

Oxidizing agents, Strong bases

Storage

Conditions for safe storage

Keep container tightly closed. Store in a cool and shaded area. Keep in a well-ventilated place. Keep under inert gas. Store locked up. Avoid shock and friction.

SECTION 8: Exposure controls/personal protection

Ingredients with workplace control parameters

Contains no substances with occupational exposure limit values.

Engineering measures

Install a closed system or local exhaust.
Also install safety shower and eye bath.

Personal protective equipment

Respiratory protection

Gas mask
Self-contained breathing apparatus

Eye/face protection

Safety glasses
Safety goggles
Face-shield

Skin and body protection

Impervious protective clothing

Hand protection

Impervious gloves *Use personal protective equipment(PPE) approved under appropriate government standards and follow local and national regulations.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

Henry's Law Constant0.143 at 25 °C (estimated using a solubility of 1,000 g/L)
Physical stateYellow liquid
Dielectric constant54.0（20℃）
Appearanceliquid
Colorwhite - yellow
OdorNo data available
Odor ThresholdNo data available
pHNo data available
Melting point/freezing pointNo data available
Boiling point/boiling range153 °C
Flash point142 °F
Evaporation rateNo data available
FlammabilityNo data available
Upper explosion limit / Upper flammability limitNo data available
Lower explosion limit / Lower flammability limitNo data available
Vapor pressure0.36 kPa (20 °C)
Relative vapor density2.56
Relative density1.01
Solubility(ies)Soluble in solvents (U.S. EPA, 1985), including ethanol and ether (Weast, 1986)
Water solubilitysoluble
Solubility in other solventssoluble Solvent: Ether soluble Solvent: Alcohol
Partition coefficient: n-octanol/water-0.57
Autoignition temperatureNo data available
Decomposition temperatureNo data available
Viscosity, dynamicNo data available
Viscosity, kinematicNo data available
Molecular weight74.08 g/mol

SECTION 10: Stability and reactivity

Reactivity

No data available

Chemical stability

Stable under normal conditions.

Possibility of hazardous reactions

May explosively decompose on heating, shock, friction, etc.

Conditions to avoid

Heat. Electrical spark Open flame Avoid shock and friction. Exposure to air.

Incompatible materials

Oxidizing agents, Strong bases

Hazardous decomposition products

Carbon monoxide, Carbon dioxide (CO2), Nitrogen oxides (NOx)

SECTION 11: Toxicological information

Acute toxicity

Product

Acute oral toxicity

Assessment: The component/mixture is highly toxic after single ingestion.

Acute inhalation toxicity

Assessment: The component/mixture is extremely toxic after short term inhalation.

Components

N-Nitrosodimethylamine

Acute oral toxicity

LD50 (Rat): 37 mg/kg Assessment: The component/mixture is highly toxic after single ingestion.

LDLo (Humans, female)

20 mg/kg

Acute inhalation toxicity

LC50 (Rat): 78 ppm Exposure time: 4 h Test atmosphere: gas Assessment: The component/mixture is extremely toxic after short term inhalation.

Acute toxicity (other routes of administration)

LD50 (Rat): 26.5 mg/kg Application Route: Intraperitoneal injection

Skin corrosion/irritation

Product

Result

Mild skin irritation

Components

N-Nitrosodimethylamine

Result

Mild skin irritation

Serious eye damage/eye irritation

Product

Result

Mild eye irritation

Components

N-Nitrosodimethylamine

RTECS No.

IQ0525000 (N-Nitrosodimethylamine)

SECTION 12: Ecological information

Ecotoxicity

Product:

Ecotoxicology Assessment

Acute aquatic toxicity

Toxic to aquatic life.

Chronic aquatic toxicity

Toxic to aquatic life with long lasting effects.

Components:

N-Nitrosodimethylamine:

Ecotoxicology Assessment

Acute aquatic toxicity

Toxic to aquatic life.

Chronic aquatic toxicity

Toxic to aquatic life with long lasting effects.

Persistence and degradability

No data available

Bioaccumulative potential

Components:

N-Nitrosodimethylamine:

octanol/water

Partition coefficient: noctanol/water

-0.57

Mobility in soil

No data available

Other adverse effects

No data available

SECTION 13: Disposal considerations

Disposal methods

Waste from residues

Disposal in accordance with local and national regulations. Take precautions against ignition or explode. Entrust disposal to a licensed waste disposal company.

Contaminated packaging

Disposal in accordance with local and national regulations. Before disposal of used container, remove contents completely.

SECTION 14: Transport information

International Regulations

IATA-DGR

Not permitted for transport

IMDG-Code

UN number

UN 3382

Proper shipping name

TOXIC BY INHALATION LIQUID, N.O.S.

Class

6.1

Packing group

EmS Code

F-A, S-A

Domestic regulation

GB 6944/12268

UN number

UN 3382

Proper shipping name

TOXIC BY INHALATION LIQUID, N.O.S.

Class

6.1

Packing group

SECTION 15: Regulatory information

Regulations on Safety Management of Hazardous Chemicals

Catalogue of Hazardous Chemicals

Listed

The ingredients of this product are reported in the following inventories

CH BAGREG

On the inventory, or in compliance with the inventory

TSCA

All substances listed as active on the TSCA inventory

AICS

On the inventory, or in compliance with the inventory

DSL

None of the components of this product are on the Canadian DSL, but all are on the NDSL
N-Nitrosodimethylamine

ENCS

Not in compliance with the inventory

ISHL

Not in compliance with the inventory

KECI

On the inventory, or in compliance with the inventory

PICCS

On the inventory, or in compliance with the inventory

IECSC

On the inventory, or in compliance with the inventory

NZIoC

Not in compliance with the inventory

SECTION 16: Other information

Abbreviations and acronyms

CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration

Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.