Chemical Safety Data Sheet MSDS / SDS
N-OCTANE
Revision Date:2026-04-04Revision Number:1
Product identifier
- Product name: N-OCTANE
- CBnumber: CB2124951
- CAS: 111-65-9
- EINECS Number: 203-892-1
- Synonyms: octane,n-Octane
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 010-86108875
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P273 Avoid release to the environment.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P331 Do NOT induce vomiting.
Hazard statements
H225 Highly Flammable liquid and vapour
H304 May be fatal if swallowed and enters airways
H315 Causes skin irritation
H336 May cause drowsiness or dizziness
H410 Very toxic to aquatic life with long lasting effects
Substance
- Product name: N-OCTANE
- Synonyms: octane,n-Octane
- CAS: 111-65-9
- EC number: 203-892-1
- MF: C8H18
- MW: 114.23
4.1 Description of first-aid measures
General adviceShow this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. Call in physician.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower.
In case of eye contact
After eye contact: rinse out with plenty of water. Remove contact lenses.
If swallowed
After swallowing: caution if victim vomits. Risk of aspiration! Keep airways free. Pulmonary failure possible after aspiration of vomit. Call a physician immediately.
4.2 Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11
4.3 Indication of any immediate medical attention and special treatment needed
No data available
4.4 Notes to physician
No data available
5.1 Extinguishing media
Suitable extinguishing mediaCarbon dioxide (CO2) Foam Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.
5.2 Special hazards arising from the substance or mixture
Carbon oxides
Combustible.
Pay attention to flashback.
Vapors are heavier than air and may spread along floors.
Development of hazardous combustion gases or vapours possible in the event of fire.
Forms explosive mixtures with air at ambient temperatures.
Combustible.
Pay attention to flashback.
Vapors are heavier than air and may spread along floors.
Development of hazardous combustion gases or vapours possible in the event of fire.
Forms explosive mixtures with air at ambient temperatures.
5.3 Advice for firefighters
Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.
Remove container from danger zone and cool with water. Prevent fire extinguishing water from contaminating surface water or the ground water system.
Remove container from danger zone and cool with water. Prevent fire extinguishing water from contaminating surface water or the ground water system.
NFPA 704
1
3
0
| HEALTH | 1 | Exposure would cause irritation with only minor residual injury (e.g. acetone, sodium bromate, potassium chloride) | |
| FIRE | 3 | Liquids and solids (including finely divided suspended solids) that can be ignited under almost all ambient temperature conditions . Liquids having a flash point below 22.8 °C (73 °F) and having a boiling point at or above 37.8 °C (100 °F) or having a flash point between 22.8 and 37.8 °C (73 and 100 °F). (e.g. gasoline, acetone) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
6.1 Personal precautions, protective equipment and emergency procedures
Advice for non-emergency personnel: Do not breathe vapors, aerosols. Avoid substance contact. Ensure adequate ventilation. Keep away from heat and sources of ignition.
Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
Evacuate the danger area, observe emergency procedures, consult an expert.
For personal protection see section 8.
6.2 Environmental precautions
Do not let product enter drains. Risk of explosion.
6.3 Methods and materials for containment and cleaning up
Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully with liquid-absorbent material (e.g.
Chemizorb®). Dispose of properly. Clean up affected area.
Chemizorb®). Dispose of properly. Clean up affected area.
6.4 Reference to other sections
For disposal see section 13.
7.1 Precautions for safe handling
Advice on safe handlingWork under hood. Do not inhale substance/mixture. Avoid generation of vapours/aerosols.
Advice on protection against fire and explosion
Keep away from open flames, hot surfaces and sources of ignition.Take precautionary measures against static discharge.
Hygiene measures
Immediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
For precautions see section 2.2.
For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Storage conditionsKeep container tightly closed in a dry and well-ventilated place. Keep away from heat and sources of ignition.
Hygroscopic.
Storage class
Hygroscopic.
Storage class (TRGS 510): 3: Flammable liquids
8.1 Control parameters
Ingredients with workplace control parameters| ['Component', 'CAS-No.', 'Value', 'Control\nparameters', 'Basis'] | ['n-octane', '111-65-9', 'PC-TWA', '500 mg/m3', 'Occupational exposure limits for\nhazardous agents in the\nworkplace - Chemical\nhazardous agents.'] |
|---|
8.2 Exposure controls
Appropriate engineering controlsImmediately change contaminated clothing. Apply preventive skin protection. Wash hands and face after working with substance.
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses
Skin protection
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0.4 mm
Break through time: 480 min
Material tested:Camatril® (KCL 730 / Aldrich Z677442, Size M)
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 30 min
Material tested:KCL 741 L
Body Protection
Internet: www.kcl.de).
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0.4 mm
Break through time: 480 min
Material tested:Camatril® (KCL 730 / Aldrich Z677442, Size M)
This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN 16523-1 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell,
Internet: www.kcl.de).
Splash contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm
Break through time: 30 min
Material tested:KCL 741 L
Flame retardant antistatic protective clothing.
Respiratory protection
required when vapours/aerosols are generated. Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.
Control of environmental exposure
Do not let product enter drains. Risk of explosion.
Information on basic physicochemical properties
- a) Physical stateliquid
- b) Colorcolorless
- c) Odorcharacteristic
- d) Melting point/freezing pointMelting point/range: -57 °C - lit.
- e) Initial boiling point and boiling range125 - 127 °C - lit.
- f) Flammability (solid, gas)No data available
- g) Upper/lower flammability or explosive limitsUpper explosion limit: 6.5 %(V)
Lower explosion limit: 0.96 %(V) - h) Flash point13 °C - closed cup
- i) Autoignition temperature220 °C
- j) Decomposition temperatureNo data available
- k) pHNo data available
- l) ViscosityViscosity, kinematic: 0.8 mm2/s at 20 °C
Viscosity, dynamic: No data available - m) Water solubilityca.0.007 g/l at 20 °C
- n) Partition coefficient n-octanol/waterlog Pow: 5.15
- o) Vapor pressure14.7 hPa at 20.0 °C
- p) Density0.703 g/cm3 at 25 °C - lit.
- Relative density0.703 g/mL at 25 °C(lit.)
- q) Relative vapor density3.9 (vs air)
- r) Particle characteristicsNo data available
- s) Explosive propertiesNo data available
- t) Oxidizing propertiesnone
- Solubilityethanol: soluble(lit.)
- Henry's Law Constant4.45 at 25 °C (Jnsson et al., 1982)
- Dielectric constant1.1（-4℃）
9.2 Other safety information
No data available
10.1 Chemical stability
The product is chemically stable under standard ambient conditions (room temperature) .
10.2 Possibility of hazardous reactions
Violent reactions possible with:
Strong oxidizing agents various plastics
Strong oxidizing agents various plastics
10.3 Conditions to avoid
Warming.
10.4 Incompatible materials
No data available
10.5 Hazardous decomposition products
In the event of fire: see section 5
11.1 Information on toxicological effects
Acute toxicityLD50 Oral - Rat - male and female - > 5,000 mg/kg (OECD Test Guideline 401)
Remarks: The value is given in analogy to the following substances: isooctane
LC50 Inhalation - Rat - male and female - 4 h - > 24.88 mg/l - vapor (OECD Test Guideline 403)
LD50 Dermal - Rabbit - male and female - > 2,000 mg/kg (OECD Test Guideline 402)
Remarks: The value is given in analogy to the following substances: isooctane
Skin corrosion/irritation
Remarks: The value is given in analogy to the following substances: isooctane
LC50 Inhalation - Rat - male and female - 4 h - > 24.88 mg/l - vapor (OECD Test Guideline 403)
LD50 Dermal - Rabbit - male and female - > 2,000 mg/kg (OECD Test Guideline 402)
Remarks: The value is given in analogy to the following substances: isooctane
Skin - Rabbit
Result: Irritating to skin. - 24 h (OECD Test Guideline 404)
Remarks: (in analogy to similar products)
The value is given in analogy to the following substances: isooctane
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Remarks: Drying-out effect resulting in rough and chapped skin.
Serious eye damage/eye irritation
Result: Irritating to skin. - 24 h (OECD Test Guideline 404)
Remarks: (in analogy to similar products)
The value is given in analogy to the following substances: isooctane
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Remarks: Drying-out effect resulting in rough and chapped skin.
Eyes - Rabbit
Result: No eye irritation (OECD Test Guideline 405)
Remarks: (in analogy to similar products)
The value is given in analogy to the following substances: isooctane
Respiratory or skin sensitization
Result: No eye irritation (OECD Test Guideline 405)
Remarks: (in analogy to similar products)
The value is given in analogy to the following substances: isooctane
Maximization Test - Guinea pig
Result: negative (OECD Test Guideline 406)
Remarks: (in analogy to similar products)
Germ cell mutagenicity
Result: negative (OECD Test Guideline 406)
Remarks: (in analogy to similar products)
Test Type: Ames test
Test system: Escherichia coli/Salmonella typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Remarks: The value is given in analogy to the following substances: n-heptaneTest Type:
Chromosome aberration test in vitro
Test system: rat hepatocytes
Method: OECD Test Guideline 473
Result: negative
Remarks: The value is given in analogy to the following substances: n-heptaneTest Type:
In vitro mammalian cell gene mutation test
Test system: human lymphoblastoid cells
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 476
Result: negative
Remarks: The value is given in analogy to the following substances: isooctaneCarcinogenicity
No data available
Reproductive toxicity
Test system: Escherichia coli/Salmonella typhimurium
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 471
Result: negative
Remarks: The value is given in analogy to the following substances: n-heptaneTest Type:
Chromosome aberration test in vitro
Test system: rat hepatocytes
Method: OECD Test Guideline 473
Result: negative
Remarks: The value is given in analogy to the following substances: n-heptaneTest Type:
In vitro mammalian cell gene mutation test
Test system: human lymphoblastoid cells
Metabolic activation: with and without metabolic activation
Method: OECD Test Guideline 476
Result: negative
Remarks: The value is given in analogy to the following substances: isooctaneCarcinogenicity
No data available
Classified based on available data. For more details, see section 2
Specific target organ toxicity - single exposure
Inhalation - May cause drowsiness or dizziness. - Central nervous system
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Specific target organ toxicity - repeated exposure
Remarks: Classified according to Regulation (EU) 1272/2008, Annex VI (Table 3.1/3.2)
Classified based on available data. For more details, see section 2
Aspiration hazard
Aspiration may cause pulmonary edema and pneumonitis.
11.2 Additional Information
RTECS: RG8400000 burning sensation, Cough, wheezing, laryngitis, Shortness of breath, Vomiting, Central nervous system depression, narcosis
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Systemic effects:
After uptake of large quantities:
Headache
Dizziness
Nausea
Vomiting agitation somnolence
Drowsiness
Unconsciousness respiratory arrest
It generally applies for aliphatic hydrocarbons with 6 - 18 carbon atoms that they may cause pneumonia, in some cases also pulmonary oedema, upon direct inhalation, i.e. in conditions that can occur only in very special circumstances (nebulizations, spraying, inhalation of aerosols and similar). After absorption of very large quantities: narcosis.
Handle in accordance with good industrial hygiene and safety practice.
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Systemic effects:
After uptake of large quantities:
Headache
Dizziness
Nausea
Vomiting agitation somnolence
Drowsiness
Unconsciousness respiratory arrest
It generally applies for aliphatic hydrocarbons with 6 - 18 carbon atoms that they may cause pneumonia, in some cases also pulmonary oedema, upon direct inhalation, i.e. in conditions that can occur only in very special circumstances (nebulizations, spraying, inhalation of aerosols and similar). After absorption of very large quantities: narcosis.
Handle in accordance with good industrial hygiene and safety practice.
12.1 Toxicity
Toxicity to fish LC50 - Oryzias latipes - 0.42 mg/l - 96.0 h
Remarks: (Lit.)
Toxicity to daphnia static test EC50 - Daphnia magna (Water flea) - 0.38 mg/l - 48 h and other aquatic Remarks: (ECOTOX Database) invertebrates
Toxicity to algae NOEC - Pseudokirchneriella subcapitata (microalgae) - 5.8 mg/l - 72 h
Remarks: (Lit.)
Toxicity to daphnia static test NOEC - Daphnia magna (Water flea) - 0.17 mg/l - 21 d and other aquatic (OECD Test Guideline 211) invertebrates(Chronic Remarks: (in analogy to similar products) toxicity)
Remarks: (Lit.)
Toxicity to daphnia static test EC50 - Daphnia magna (Water flea) - 0.38 mg/l - 48 h and other aquatic Remarks: (ECOTOX Database) invertebrates
Toxicity to algae NOEC - Pseudokirchneriella subcapitata (microalgae) - 5.8 mg/l - 72 h
Remarks: (Lit.)
Toxicity to daphnia static test NOEC - Daphnia magna (Water flea) - 0.17 mg/l - 21 d and other aquatic (OECD Test Guideline 211) invertebrates(Chronic Remarks: (in analogy to similar products) toxicity)
12.2 Persistence and degradability
Biodegradability aerobic - Exposure time 10 d
Result: 70.3 % - Readily biodegradable.
Remarks: (ECHA)
Theoretical oxygen 3,500 mg/g demand Remarks: (Lit.)
Result: 70.3 % - Readily biodegradable.
Remarks: (ECHA)
Theoretical oxygen 3,500 mg/g demand Remarks: (Lit.)
12.3 Bioaccumulative potential
No data available
12.4 Mobility in soil
No data available
12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
12.6 Endocrine disrupting properties
No data available
12.7 Other adverse effects
No data available
13.1 Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company.
Offer surplus and non-recyclable solutions to a licensed disposal company.
14.1 UN number
ADR/RID: 1262
IMDG: 1262
IATA-DGR: 1262
IMDG: 1262
IATA-DGR: 1262
14.2 UN proper shipping name
ADR/RID: OCTANES
IMDG: OCTANES
IATA-DGR: Octanes
IMDG: OCTANES
IATA-DGR: Octanes
14.3 Transport hazard class(es)
ADR/RID: 3
IMDG: 3
IATA-DGR: 3
IMDG: 3
IATA-DGR: 3
14.4 Packaging group
ADR/RID: II
IMDG: II
IATA-DGR: II
IMDG: II
IATA-DGR: II
14.5 Environmental hazards
ADR/RID: yes
IMDG Marine pollutant: yes
IATA-DGR: no
IMDG Marine pollutant: yes
IATA-DGR: no
14.6 Special precautions for user
Based on chemical properties, choose appropriate tools and conditions of transport.
Transporting tools shall be equipped with appropriate and sufficient firefighting equipment and emergency leaking installations. If transporting by road, please go along the specified route.
Transporting tools shall be equipped with appropriate and sufficient firefighting equipment and emergency leaking installations. If transporting by road, please go along the specified route.
14.7 Incompatible materials
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture
National regulatory information
Law on the Prevention and Control of Occupational Diseases
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals : Listed
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Law on the Prevention and Control of Occupational Diseases
Regulations on Safety Management of Hazardous Chemicals
Catalogue of Hazardous Chemicals : Listed
Other regulations
Please pay attention on the waste treatment should also comply with local regulations requirement.
Abbreviations and acronyms
CAS: Chemical Abstracts Service
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
TWA: Time-Weighted Average
STEL: Short-Term Exposure Limit
LD50: Lethal Dose 50%
LC50: Lethal Concentration 50%
EC50: Effective Concentration 50%
PEL: Permissible Exposure Limit
TLV: Threshold Limit Value
IMDG: International Maritime Dangerous Goods Code
IATA: International Air Transport Association
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
DOT: US Department of Transportation
NFPA: National Fire Protection Association
NIOSH: National Institute for Occupational Safety and Health
OSHA: Occupational Safety and Health Administration
Disclaimer:
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.