Chemical Safety Data Sheet MSDS / SDS

N,N-DIMETHYLTHIOFORMAMIDE

Revision Date:2026-03-21Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

Product name: N,N-DIMETHYLTHIOFORMAMIDE
CBnumber: CB2229056
CAS: 758-16-7
EINECS Number: 212-060-7
Synonyms: HCSN(CH3)2;NSC 402082

Relevant identified uses of the substance or mixture and uses advised against

Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
Uses advised against: none

Company Identification

Company: Chemicalbook
Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
Telephone: 010-86108875

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

Symbol(GHS)

Signal wordWarning

Precautionary statements

P264 Wash skin thouroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P501 Dispose of contents/container to..…

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405 Store locked up.

Hazard statements

H311 Toxic in contact with skin

H315 Causes skin irritation

H319 Causes serious eye irritation

H332 Harmful if inhaled

H335 May cause respiratory irritation

H301 Toxic if swalloed

SECTION 3: Composition/information on ingredients

Substance

Product name: N,N-DIMETHYLTHIOFORMAMIDE
Synonyms: HCSN(CH3)2;NSC 402082
CAS: 758-16-7
EC number: 212-060-7
MF: C3H7NS
MW: 89.16

SECTION 4: First aid measures

If inhaled

After inhalation: fresh air.

In case of skin contact

In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower.

In case of eye contact

After eye contact: rinse out with plenty of water. Remove contact lenses.

If swallowed

After swallowing: make victim drink water (two glass- es at most). Consult doctor if feeling unwell.

Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2) and/or in section 11

Protection of first-aiders

For personal protection see section 8.

Notes to physician

No data available

SECTION 5: Firefighting measures

Suitable extinguishing media

Water Foam Carbon dioxide (CO2) Dry powder

Unsuitable extinguishing media

For this substance/mixture no limitations of extinguishing agents are given.

Specific hazards during fire fighting

Combustible. Vapours are heavier than air and may spread along floors. Forms explosive mixtures with air on intense heating. Development of hazardous combustion gases or vapours possible in the event of fire.

Hazardous combustion products

Carbon oxides Nitrogen oxides (NOx) Sulphur oxides

Specific extinguishing methods

Suppress (knock down) gases/vapours/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.

Special protective equipment for fire-fighters

In the event of fire, wear self-contained breathing apparatus.

NFPA 704

HEALTH	2	Intense or continued but not chronic exposure could cause temporary incapacitation or possible residual injury (e.g. diethyl ether, ammonium phosphate, iodine)
FIRE	0	Materials that will not burn under typical fire conditions, including intrinsically noncombustible materials such as concrete, stone, and sand. Materials that will not burn in air when exposed to a temperature of 820 °C (1,500 °F) for a period of 5 minutes.(e.g. Carbon tetrachloride)
REACT	0	Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2)
SPEC. HAZ.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Advice for non-emergency personnel: Do not breathe vapours, aerosols. Evacuate the danger area, observe emergency procedures, consult an expert. Advice for emergency responders: For personal protection see section 8.

Environmental precautions

Do not let product enter drains.

Methods and materials for containment and cleaning up

Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up with liquid-absorbent material (e.g. Chemizorb® ). Dispose of properly. Clean up affected area.

SECTION 7: Handling and storage

Handling

Avoidance of contact

Strong bases

Storage

Further information on storage conditions

Tightly closed. Keep in a well-ventilated place. Keep locked up or in an area accessible only to qualified or authorised persons.

Storage class

6.1C, Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Recommended storage temperature

Recommended storage temperature see product label.

SECTION 8: Exposure controls/personal protection

Ingredients with workplace control parameters

Contains no substances with occupational exposure limit values.

Engineering measures

No data available

Personal protective equipment

Respiratory protection

Not required; except in case of aerosol formation.

Eye/face protection

Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Safety glasses

Hygiene measures

Change contaminated clothing. Wash hands after working with substance.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

Dielectric constant47.5
Solubilitysol THF, ethyl acetate, toluene, DMF
Physical stateliquid
Viscosity, dynamicNo data available
Decomposition temperatureNo data available
Autoignition temperatureNo data available
Partition coefficient: n-octanol/waterNo data available
Water solubilityFully miscible in water.
Density1.047 g/mL (25 °C)
Method: lit.
Relative density1.047 g/mL at 25 °C(lit.)
Relative vapor densityNo data available
Vapor pressureNo data available
Lower explosion limit / Lower flammability limitNo data available
Upper explosion limit / Upper flammability limitNo data available
Burning rateNo data available
Flammability (liquids)No data available
Flammability (solid, gas)No data available
Evaporation rateNo data available
Flash point99 °C
Method: closed cup
Boiling point/boiling range58 - 60 °C (1 hPa)
Method: lit.
Melting point/ rangeNo data available
pHNo data available
Odor ThresholdNo data available
OdorNo data available
Colordark yellow
Appearanceclear, liquid
Particle characteristics Particle sizeNo data available
Molecular weight89.16 g/mol
Oxidizing propertiesnone
Explosive propertiesNo data available
Flow timeNo data available
Viscosity, kinematicNo data available

SECTION 10: Stability and reactivity

Reactivity

Forms explosive mixtures with air on intense heating. A range from approx. 15 Kelvin below the flash point is to be rated as critical.

Chemical stability

The product is chemically stable under standard ambient conditions (room temperature) .

Possibility of hazardous reactions

No data available

Conditions to avoid

Strong heating.

Incompatible materials

Strong bases

Hazardous decomposition products

In the event of fire: see section 5

SECTION 11: Toxicological information

11.1 Information on toxicological effects

Acute toxicity

Oral: No data available
Inhalation: No data available
Dermal: No data available

Skin corrosion/irritation

Remarks: No data available

Serious eye damage/eye irritation

Remarks: No data available

Respiratory or skin sensitization