Oxobutanedioic acid
Product identifier
- Product name: Oxobutanedioic acid
- CBnumber: CB0271682
- CAS: 328-42-7
- EINECS Number: 206-329-8
- Synonyms: Oxaloacetic acid,oxalacetic acid
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
GHS Label elements, including precautionary statements
-
Symbol(GHS)
- Signal wordDanger
Substance
- Product name: Oxobutanedioic acid
- Synonyms: Oxaloacetic acid,oxalacetic acid
- CAS: 328-42-7
- EC number: 206-329-8
- MF: C4H4O5
- MW: 132.07
Description of first aid measures
General adviceMost important symptoms and effects, both acute and delayed
Indication of any immediate medical attention and special treatment needed
Notes to physician
Extinguishing media
Suitable extinguishing mediaSpecial hazards arising from the substance or mixture
Carbon oxides
Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
NFPA 704
| HEALTH | 3 | Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid) | |
| FIRE | 1 | Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Avoid breathing dust.
For personal protection see section 8.
Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.
Reference to other sections
For disposal see section 13.
Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature -20 °C
control parameter
Hazard composition and occupational exposure limitsExposure controls
Appropriate engineering controlsHandle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
Safety glasses with side-shields conforming to EN166 Use equipment for eye
protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
Full contact
Material: Nitrile rubber
Minimum layer thickness: 0.11 mm Break through time: 480 min
Material tested:Dermatril? (KCL 740 / Aldrich Z677272, Size M)
Splash contact Material: Nitrile rubber
Minimum layer thickness: 0.11 mm Break through time: 480 min
Material tested:Dermatril? (KCL 740 / Aldrich Z677272, Size M)
data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374
If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.
Impervious clothing, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.
For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle respirator.For higher level protection use type OV/AG/P99 (US) or type ABEK-P2 (EU EN 143) respirator cartridges. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).
Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.
Information on basic physicochemical properties
- Appearancewhite powder
- OdourNo data available
- Odour ThresholdNo data available
- pHNo data available
- Melting point/freezing point153.5 °C at 1,013.25 hPa - OECD Test Guideline 102 - (decomposition)
- Initial boiling point and boiling rangeDecomposes below the boiling point.
- Flash point88°C
- Evaporation rateNo data available
- Flammability (solid, gas)does not ignite - Test N.1: Test method for readily combustible solids
- Upper/lower flammability or explosive limitsNo data available
- Vapour pressure< 0.01 hPa at 20 °C - OECD Test Guideline 104
- Vapour densityNo data available
- Relative density1.6081 g/cm3 at 20 °C - OECD Test Guideline 109
- Water solubility1,000 g/l at 20 °C - OECD Test Guideline 105
- Partition coefficient: n-octanol/waterlog Pow: -1.04 at 20 °C - OECD Test Guideline 107 - Bioaccumulation is not expected.
- Autoignition temperature does not ignite
- Decomposition temperature>153.5 °C -
- ViscosityNo data available
- Explosive propertiesNo data available
- Oxidizing propertiesNo data available
Other safety information
Bulk density 0.18 g/l
Chemical stability
Stable under recommended storage conditions.
Possibility of hazardous reactions
No data available
Conditions to avoid
No data available
Incompatible materials
Strong oxidizing agents, Acids, Bases
Hazardous decomposition products
Hazardous decomposition products formed under fire conditions. - Carbon oxides Other decomposition products - No data available
In the event of fire: see section 5
Information on toxicological effects
Acute toxicityResult: No skin irritation - 4 h (OECD Test Guideline 404)
(OECD Test Guideline 492)
Result: negative
(OECD Test Guideline 442C) In vitro study
Result: negative
(OECD Test Guideline 442D)
Escherichia coli/Salmonella typhimurium Result: negative
Cough, Shortness of breath, Headache, Nausea, Vomiting
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
Toxicity
No data available
static test EC50 - Daphnia magna (Water flea) - > 100 mg/l - 48 h (OECD Test Guideline 202)
31.19 mg/l - 72 h
(OECD Test Guideline 201)
static test NOEC - Pseudokirchneriella subcapitata (green algae) -
3.28 mg/l - 72 h
(OECD Test Guideline 201)
Persistence and degradability
Biodegradability aerobic - Exposure time 28 d
Result: 86 % - Readily biodegradable. (OECD Test Guideline 301D)
Bioaccumulative potential
No data available
Mobility in soil
No data available
Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
Other adverse effects
Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.
Contaminated packaging
Dispose of as unused product.
UN number
ADR/RID: - IMDG: - IATA-DGR: -
UN proper shipping name
Transport hazard class(es)
ADR/RID: - IMDG: - IATA-DGR: -
Packaging group
ADR/RID: - IMDG: - IATA-DGR: -
Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA-DGR: no
Special precautions for user
Based on chemical properties, choose appropriate tools and conditions of t appropriate and sufficient firefighting equipment and emergency leaking i specified route.
Incompatible materials
Strong oxidizing agents, Acids, Bases
Safety, health and environmental regulations/legislation specific for the substance or mixture
Regulations on the Safety Management of Hazardous ChemicalsAbbreviations and acronyms
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- CAS: Chemical Abstracts Service
- EC50: Effective Concentration 50%
- IATA: International Air Transportation Association
- IMDG: International Maritime Dangerous Goods
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- STEL: Short term exposure limit
- TWA: Time Weighted Average
References
【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/
【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.