Chemical Safety Data Sheet MSDS / SDS

Phenylhydrazine

Revision Date:2022-12-24Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

  • Product name: Phenylhydrazine
  • CBnumber: CB9216819
  • CAS: 100-63-0
  • EINECS Number: 202-873-5
  • Synonyms: phenylhydrazine,Phenyl hydrazide

Relevant identified uses of the substance or mixture and uses advised against

  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none

Company Identification

  • Company: Chemicalbook
  • Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
  • Telephone: 400-158-6606

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

  • Symbol(GHS)
  • Signal wordDanger
Precautionary statements
P405 Store locked up.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P273 Avoid release to the environment.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P201 Obtain special instructions before use.
Hazard statements
H400 Very toxic to aquatic life
H372 Causes damage to organs through prolonged or repeated exposure
H350 May cause cancer
H341 Suspected of causing genetic defects
H331 Toxic if inhaled
H319 Causes serious eye irritation
H317 May cause an allergic skin reaction
H315 Causes skin irritation
H311 Toxic in contact with skin
H301 Toxic if swalloed
H227 Combustible liquid

SECTION 3: Composition/information on ingredients

Substance

  • Product name: Phenylhydrazine
  • Synonyms: phenylhydrazine,Phenyl hydrazide
  • CAS: 100-63-0
  • EC number: 202-873-5
  • MF: C6H8N2
  • MW: 108.14

SECTION 4: First aid measures

Description of first aid measures

General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician.
In case of eye contact
Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.
If swallowed
Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11

Indication of any immediate medical attention and special treatment needed

No data available

Notes to physician

No data available

SECTION 5: Firefighting measures

Extinguishing media

Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Unsuitable extinguishing media
Do NOT use water jet.

Special hazards arising from the substance or mixture

Carbon oxides, Nitrogen oxides (NOx)

Advice for firefighters

Wear self-contained breathing apparatus for firefighting if necessary. Use water spray to cool unopened containers.

NFPA 704

3
2
0
HEALTH 3 Short exposure could cause serious temporary or moderate residual injury (e.g. liquid hydrogen, sulfuric acid, calcium hypochlorite, hexafluorosilicic acid)
FIRE 2 Must be moderately heated or exposed to relatively high ambient temperature before ignition can occur and multiple finely divided suspended solids that do not require heating before ignition can occur. Flash point between 37.8 and 93.3 °C (100 and 200 °F). (e.g. diesel fuel, sulfur)
REACT 0 Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2)
SPEC. HAZ.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Wear respiratory protection. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Remove all sources of ignition. Evacuate personnel to safe areas. Beware of vapours accumulating to form explosive concentrations. Vapours can accumulate in low areas.

For personal protection see section 8.

Environmental precautions

Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.

Methods and materials for containment and cleaning up

Contain spillage, and then collect with non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite) and place in container for disposal according to local / national regulations (see section 13). Keep in suitable, closed containers for disposal.

Reference to other sections

For disposal see section 13.

SECTION 7: Handling and storage

Precautions for safe handling

Avoid exposure - obtain special instructions before use.Avoid contact with skin and eyes. Avoid inhalation of vapour or mist.

Keep away from sources of ignition - No smoking.Take measures to prevent the build up of electrostatic charge.

For precautions see section 2.2.

Conditions for safe storage, including any incompatibilities

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

Light sensitive. Store under inert gas. Air sensitive.

SECTION 8: Exposure controls/personal protection

control parameter

Hazard composition and occupational exposure limits
Does not contain substances with occupational exposure limits.

Exposure controls

Appropriate engineering controls

Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product.

Personal protective equipment
Eye/face protection

Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.

The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.

Full contact

Material: butyl-rubber

Minimum layer thickness: 0.3 mm Break through time: 480 min

Material tested:Butoject? (KCL 897 / Aldrich Z677647, Size M)

Splash contact Material: Chloroprene

Minimum layer thickness: 0.6 mm Break through time: 120 min

Material tested:Camapren? (KCL 722 / Aldrich Z677493, Size M)

data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374

If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.

Body Protection

Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.

Respiratory protection

Where risk assessment shows air-purifying respirators are appropriate use a full- face respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).

Control of environmental exposure

Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.

Exposure limits
TLV-TWA skin 0.1 ppm (0.44 mg/m3) (ACGIH), 5 ppm (22 mg/m3) (OSHA); STEL 10 ppm (44 mg/m3) (OSHA); carcinogenicity: A2-Suspected Human Carcinogen (ACGIH), Carcinogen (NIOSH). .

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

  • AppearanceForm: liquid
  • OdourNo data available
  • Odour ThresholdNo data available
  • pHNo data available
  • Melting point/freezing pointMelting point/range: 18 - 21 °C
  • Initial boiling point and boiling range238 - 241 °C
  • Flash point89 °C - closed cup
  • Evaporation rateNo data available
  • Flammability (solid, gas)No data available
  • Upper/lower flammability or explosive limits Lower explosion limit: 1.1 %(V)
  • Vapour pressure1.35 hPa at 60 °C
  • Vapour density4.33
  • Relative density1.098 g/mL
  • Water solubilitySoluble in dilute acids.
  • Partition coefficient: n-octanol/waterNo data available
  • Autoignition temperatureNo data available
  • Decomposition temperatureNo data available
  • ViscosityNo data available
  • Explosive propertiesNo data available
  • Oxidizing propertiesNo data available

Other safety information

Surface tension 46.1 mN/m at 20 °C


Relative vapour density

4.33

SECTION 10: Stability and reactivity

Chemical stability

Stable under recommended storage conditions.

Possibility of hazardous reactions

No data available

Conditions to avoid

Heat, flames and sparks.

Incompatible materials

Oxidizing agents

Hazardous decomposition products

Hazardous decomposition products formed under fire conditions. - Carbon oxides, Nitrogen oxides (NOx)

Other decomposition products - No data available In the event of fire: see section 5

SECTION 11: Toxicological information

Information on toxicological effects

Acute toxicity
LD50 Oral - Rat - 188 mg/kg
Remarks: Behavioral:Excitement. Behavioral:Muscle contraction or spasticity.
LC50 Inhalation - Rat - 2,610 mg/m3 LC50 Inhalation - Mouse - 2,120 mg/m3
Skin corrosion/irritation
No data available
Serious eye damage/eye irritation Respiratory or skin sensitisation
Hazardous polymerisation may occur.
Germ cell mutagenicity
In vitro tests showed mutagenic effects Ames test
S. typhimurium
Histidine reversion (Ames)
Mouse
DNA damage
Carcinogenicity
Possible human carcinogen
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure Aspiration hazard
No data available
Additional Information
RTECS: MV8925000
Liver injury may occur., Kidney injury may occur., Blood disorders
Toxicity
LD50 orally in Rabbit: 188 mg/kg

SECTION 12: Ecological information

Toxicity

Toxicity to fish
LC50 - Danio rerio (zebra fish) - 0.16 - 0.25 mg/l - 48.0 h

Toxicity to daphnia and other aquatic invertebrates

EC50 - Daphnia magna (Water flea) - 2 - 5 mg/l - 48 h

Toxicity to algae
EC50 - Desmodesmus subspicatus (green algae) - 3.2 mg/l

Persistence and degradability

Biodegradability Biotic/Aerobic - Exposure time 28 d

Result: 97 % - Readily biodegradable.

Bioaccumulative potential


No data available

Mobility in soil

No data available

Results of PBT and vPvB assessment

PBT/vPvB assessment not available as chemical safety assessment not required/not conducted

Other adverse effects

Very toxic to aquatic life.

SECTION 13: Disposal considerations

Waste treatment methods

Product

Offer surplus and non-recyclable solutions to a licensed disposal company. This combustible material may be burned in a chemical incinerator equipped with an afterburner and scrubber.

Incompatibilities

Phenylhydrazine is very reactive with carbonyl compounds, strong oxidizers; strong bases; alkali metals; ammonia, lead dioxide (violent). Attacks copper salts, nickel, and chromates.

Waste Disposal

Controlled incineration whereby oxides of nitrogen are removed from the effluent gas by scrubber, catalytic or thermal device.

Contaminated packaging

Dispose of as unused product.


SECTION 14: Transport information

UN number

ADR/RID: 2572 IMDG: 2572 IATA-DGR: 2572

UN proper shipping name

ADR/RID: PHENYLHYDRAZINE IMDG: PHENYLHYDRAZINE IATA-DGR: Phenylhydrazine

Transport hazard class(es)

ADR/RID: 6.1 IMDG: 6.1 IATA-DGR: 6.1

Packaging group

ADR/RID: II IMDG: II IATA-DGR: II

Environmental hazards

ADR/RID: yes IMDG Marine pollutant: yes IATA-DGR: no

Special precautions for user

Based on chemical properties, choose appropriate tools and conditions of transport. Transporting tools shall be equipped with appropriate and sufficient firefighting equipment and emergency leaking installations. If transporting by road, please go along the specified route.

Incompatible materials

Oxidizing agents

SECTION 15: Regulatory information

Safety, health and environmental regulations/legislation specific for the substance or mixture

Regulations on the Safety Management of Hazardous Chemicals
China Catalog of Hazardous chemicals 2015:Listed. website: https://www.mem.gov.cn/
Measures for Environmental Management of New Chemical Substances
United States Toxic Substances Control Act (TSCA) Inventory:Listed. website: https://www.epa.gov/
European Inventory of Existing Commercial Chemical Substances (EINECS):Listed. website: https://echa.europa.eu/
EC Inventory:Listed.
New Zealand Inventory of Chemicals (NZIoC):Listed. website: https://www.epa.govt.nz/
Vietnam National Chemical Inventory:Listed. website: https://chemicaldata.gov.vn/
Philippines Inventory of Chemicals and Chemical Substances (PICCS):Listed. website: https://emb.gov.ph/
Korea Existing Chemicals List (KECL):Listed. website: http://ncis.nier.go.kr
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC):Listed. website: https://www.mee.gov.cn/

SECTION 16: Other information

Abbreviations and acronyms

  • CAS: Chemical Abstracts Service
  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • IMDG: International Maritime Dangerous Goods
  • IATA: International Air Transportation Association
  • TWA: Time Weighted Average
  • STEL: Short term exposure limit
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • EC50: Effective Concentration 50%

References

【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple

【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp

【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/

【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en

【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg

【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp

【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm

【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/

【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home

【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/

Other Information

The symptoms of hemolysis do not become manifest until hours have passed.Do NOT take working clothes home.
Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.

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