Chemical Safety Data Sheet MSDS / SDS

Potassium hydrogen phthalate

Revision Date:2023-11-29Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

Product name: Potassium hydrogen phthalate
CBnumber: CB1132397
CAS: 877-24-7
EINECS Number: 212-889-4
Synonyms: PBS,buffer

Relevant identified uses of the substance or mixture and uses advised against

Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
Uses advised against: none

Company Identification

Company: Chemicalbook
Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
Telephone: 400-158-6606

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

Hazard statements

H303 May be harmfulif swallowed

SECTION 3: Composition/information on ingredients

Substance

Product name: Potassium hydrogen phthalate
Synonyms: PBS,buffer
CAS: 877-24-7
EC number: 212-889-4
MF: C8H5KO4
MW: 204.22

SECTION 4: First aid measures

Description of first aid measures

If inhaled

After inhalation: fresh air.

In case of skin contact

In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower.

In case of eye contact

After eye contact: rinse out with plenty of water. Remove contact lenses.

If swallowed

After swallowing: make victim drink water (two glasses at most). Consult doctor if feeling unwell.

Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11

Indication of any immediate medical attention and special treatment needed

No data available

SECTION 5: Firefighting measures

Extinguishing media

Suitable extinguishing media

Water Foam Carbon dioxide (CO2) Dry powder

Unsuitable extinguishing media

For this substance/mixture no limitations of extinguishing agents are given.

Special hazards arising from the substance or mixture

Carbon oxides Potassium oxides Combustible.

Vapors are heavier than air and may spread along floors. Forms explosive mixtures with air on intense heating.

Development of hazardous combustion gases or vapours possible in the event of fire.

Advice for firefighters

In the event of fire, wear self-contained breathing apparatus.

Further information

Prevent fire extinguishing water from contaminating surface water or the ground water system.

NFPA 704

HEALTH	1	Exposure would cause irritation with only minor residual injury (e.g. acetone, sodium bromate, potassium chloride)
FIRE	1	Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia)
REACT	0	Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2)
SPEC. HAZ.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Advice for non-emergency personnel: Avoid inhalation of dusts. Evacuate the danger area, observe emergency procedures, consult an expert.

For personal protection see section 8.

Environmental precautions

Do not let product enter drains.

Methods and materials for containment and cleaning up

Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up dry. Dispose of properly. Clean up affected area. Avoid generation of dusts.

Reference to other sections

For disposal see section 13.

SECTION 7: Handling and storage

Precautions for safe handling

For precautions see section 2.2.

Conditions for safe storage, including any incompatibilities

Storage conditions

Tightly closed. Dry.

Moisture sensitive.

Storage class

Storage class (TRGS 510): 13: Non Combustible Solids

Specific end use(s)

Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

control parameter

Hazard composition and occupational exposure limits

Does not contain substances with occupational exposure limits.

Exposure controls

Personal protective equipment

Eye/face protection

Use equipment for eye protection tested and approved under appropriate

government standards such as NIOSH (US) or EN 166(EU). Safety glasses

Skin protection

Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.

The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.

Full contact

Material: Nitrile rubber

Minimum layer thickness: 0,11 mm Break through time: 480 min

Material tested:Dermatril? (KCL 740 / Aldrich Z677272, Size M)

Splash contact Material: Nitrile rubber

Minimum layer thickness: 0,11 mm Break through time: 480 min

Material tested:Dermatril? (KCL 740 / Aldrich Z677272, Size M)

data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374

If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the EC approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.

Respiratory protection

required when dusts are generated.

Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.

Recommended Filter type: Filter type P1

The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.

These measures have to be properly documented.

Control of environmental exposure

Do not let product enter drains.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

Appearancewhite Crystalline solid
OdourNo data available
Odour ThresholdNo data available
pH4 at 25 °C
Melting point/freezing pointpoint/range: 295 - 300 °C - dec.
Initial boiling point and boiling range>300 °C at 977,5 hPa - OECD Test Guideline 103
Flash point197,3 °C - Pensky-Martens closed cup
Evaporation rateNo data available
Flammability (solid, gas)The product is not flammable. - Regulation (EC) No. 440/2008, Annex, A.10
Upper/lower flammability or explosive limitsNo data available
Vapour pressure No data available
Vapour density No data available
Relative density1,571 g/cm3 at 20 °C No data available
Water solubility93 g/l at 30 °C - OECD Test Guideline 105
Partition coefficient: n-octanol/waterlog Pow:<= -3,9 at 30 °C - Bioaccumulation is not expected.
Autoignition temperaturedoes not ignite
Decomposition temperature No data available
ViscosityViscosity, kinematic: No data available Viscosity, dynamic: No data available
Explosive propertiesNo data available
Oxidizing propertiesnone

Other safety information

No data available

SECTION 10: Stability and reactivity

Reactivity

Forms explosive mixtures with air on intense heating.

A range from approx. 15 Kelvin below the flash point is to be rated as critical.

The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.

Chemical stability

The product is chemically stable under standard ambient conditions (room temperature) .

Possibility of hazardous reactions

Violent reactions possible with: Strong oxidizing agents

Nitric acid

Conditions to avoid

Strong heating.

Incompatible materials

No data available

Hazardous decomposition products

In the event of fire: see section 5

SECTION 11: Toxicological information

Information on toxicological effects

Acute toxicity

LD50 Oral - Rat - > 3.200 mg/kg
Remarks: (ECHA) Inhalation

Skin corrosion/irritation

slight irritation

Serious eye damage/eye irritation

Eyes - Rabbit
Result: No eye irritation
Remarks: The value is given based on a SAR/AAR approach using OECD Toolbox, DEREK, VEGA QSAR models (CAESAR models), etc.
(ECHA)

Respiratory or skin sensitization

In vitro study Result: negative
(OECD Test Guideline 442D)

Germ cell mutagenicity

Test Type: Ames test
Test system: S. typhimurium
Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 471
Result: negative

Carcinogenicity

No data available

Reproductive toxicity

No data available

Specific target organ toxicity - single exposure

No data available

Specific target organ toxicity - repeated exposure

No data available

Aspiration hazard

No data available

Toxicity

LD50 orally in Rabbit: > 3200 mg/kg

SECTION 12: Ecological information

Toxicity

Toxicity to fish

static test LC50 - Danio rerio (zebra fish) - > 100 mg/l - 96 h (OECD Test Guideline 203)

Toxicity to algae

static test ErC50 - Desmodesmus subspicatus (green algae) - 329,5 mg/l - 72 h

(OECD Test Guideline 201)

Toxicity to bacteria

Remarks: (ECHA)

(potassium hydrogen phthalate)

Persistence and degradability

Biodegradability Result: 97,34 % - Readily biodegradable.

(OECD Test Guideline 301D)

Bioaccumulative potential

No data available

Mobility in soil

No data available

Results of PBT and vPvB assessment

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

Other adverse effects

Discharge into the environment must be avoided.

SECTION 13: Disposal considerations

Waste treatment methods

Product

See www.retrologistik.com for processes regarding the return of chemicals and containers, or contact us there if you have further questions.

SECTION 14: Transport information

UN number

ADR/RID: - IMDG: - IATA: -

UN proper shipping name

ADR/RID: Not dangerous goods IMDG: Not dangerous goods IATA: Not dangerous goods

Transport hazard class(es)

ADR/RID: - IMDG: - IATA: -

Packaging group

ADR/RID: - IMDG: - IATA: -

Environmental hazards

ADR/RID: no IMDG Marine pollutant: no IATA: no

Special precautions for user

Further information

Not classified as dangerous in the meaning of transport regulations.

SECTION 15: Regulatory information

Safety, health and environmental regulations/legislation specific for the substance or mixture

Regulations on the Safety Management of Hazardous Chemicals

China Catalog of Hazardous chemicals 2015:Not Listed. website: https://www.mem.gov.cn/

Measures for Environmental Management of New Chemical Substances

Chinese Chemical Inventory of Existing Chemical Substances (China IECSC):Listed. website: https://www.mee.gov.cn/

EC Inventory:Listed.

European Inventory of Existing Commercial Chemical Substances (EINECS):Listed. website: https://echa.europa.eu/

Korea Existing Chemicals List (KECL):Listed. website: http://ncis.nier.go.kr

New Zealand Inventory of Chemicals (NZIoC):Listed. website: https://www.epa.govt.nz/

Philippines Inventory of Chemicals and Chemical Substances (PICCS):Listed. website: https://emb.gov.ph/

United States Toxic Substances Control Act (TSCA) Inventory:Listed. website: https://www.epa.gov/

Vietnam National Chemical Inventory:Listed. website: https://chemicaldata.gov.vn/

SECTION 16: Other information

Abbreviations and acronyms

ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
CAS: Chemical Abstracts Service
EC50: Effective Concentration 50%
IATA: International Air Transportation Association
IMDG: International Maritime Dangerous Goods
LC50: Lethal Concentration 50%
LD50: Lethal Dose 50%
RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
STEL: Short term exposure limit
TWA: Time Weighted Average

References

【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple

【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp

【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/

【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en

【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg

【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp

【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm

【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/

【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home

【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/

Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.