Chemical Safety Data Sheet MSDS / SDS

Tetramethylammonium hydroxide pentahydrate

Revision Date:2023-12-07Revision Number:1

SECTION 1: Identification of the substance/mixture and of the company/undertaking

Product identifier

  • Product name: Tetramethylammonium hydroxide pentahydrate
  • CBnumber: CB7111710
  • CAS: 10424-65-4
  • EINECS Number: 629-762-8
  • Synonyms: tetramethylammonium hydroxide pentahydrate,ETRAMETHYLAMMONIUM HYDROXIDE PENTAHYDRATE

Relevant identified uses of the substance or mixture and uses advised against

  • Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
  • Uses advised against: none

Company Identification

  • Company: Chemicalbook
  • Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
  • Telephone: 400-158-6606

SECTION 2: Hazards identification

GHS Label elements, including precautionary statements

  • Symbol(GHS)
  • Signal wordDanger
Precautionary statements
P405 Store locked up.
P310 Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P264 Wash skin thouroughly after handling.
P264 Wash hands thoroughly after handling.
Hazard statements
H411 Toxic to aquatic life with long lasting effects
H372 Causes damage to organs through prolonged or repeated exposure
H370 Causes damage to organs
H318 Causes serious eye damage
H314 Causes severe skin burns and eye damage
H311 Toxic in contact with skin
H300 Fatal if swallowed

SECTION 3: Composition/information on ingredients

Substance

  • Product name: Tetramethylammonium hydroxide pentahydrate
  • Synonyms: tetramethylammonium hydroxide pentahydrate,ETRAMETHYLAMMONIUM HYDROXIDE PENTAHYDRATE
  • CAS: 10424-65-4
  • EC number: 629-762-8
  • MF: C4H23NO6
  • MW: 181.23

SECTION 4: First aid measures

Description of first aid measures

General advice
First aiders need to protect themselves. Show this material safety data sheet to the doctor in attendance.
If inhaled
After inhalation: fresh air. Immediately call in physician. If breathing stops: immediately apply artificial respiration, if necessary also oxygen.
In case of skin contact
In case of skin contact: Take off immediately all contaminated clothing. Rinse skin with water/ shower. Call a physician immediately.
In case of eye contact
After eye contact: rinse out with plenty of water. Immediately call in ophthalmologist. Remove contact lenses.
If swallowed
If swallowed: give water to drink (two glasses at most). Seek medical advice immediately. In exceptional cases only, if medical care is not available within one hour, induce vomiting (only in persons who are wide awake and fully conscious), administer activated charcoal (20 - 40 g in a 10% slurry) and consult a doctor as quickly as possible. Do not attempt to neutralise.

Most important symptoms and effects, both acute and delayed

The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11

Indication of any immediate medical attention and special treatment needed

No data available

SECTION 5: Firefighting measures

Extinguishing media

Suitable extinguishing media
Water Foam Carbon dioxide (CO2) Dry powder
Unsuitable extinguishing media
For this substance/mixture no limitations of extinguishing agents are given.

Special hazards arising from the substance or mixture

Carbon oxides Nitrogen oxides (NOx) Combustible.

Development of hazardous combustion gases or vapours possible in the event of fire.

Advice for firefighters

Stay in danger area only with self-contained breathing apparatus. Prevent skin contact by keeping a safe distance or by wearing suitable protective clothing.

Further information

Suppress (knock down) gases/vapors/mists with a water spray jet. Prevent fire extinguishing water from contaminating surface water or the ground water system.

NFPA 704

4
1
1
HEALTH 4 Very short exposure could cause death or major residual injury (e.g. hydrogen cyanide, phosgene, methyl isocyanate, hydrofluoric acid)
FIRE 1 Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia)
REACT 1 Normally stable, but can become unstable at elevated temperatures and pressures (e.g. propene)
SPEC. HAZ.

SECTION 6: Accidental release measures

Personal precautions, protective equipment and emergency procedures

Advice for non-emergency personnel: Avoid generation and inhalation of dusts in all circumstances. Avoid substance contact. Ensure adequate ventilation. Evacuate the danger area, observe emergency procedures, consult an expert.

For personal protection see section 8.

Environmental precautions

Do not let product enter drains.

Methods and materials for containment and cleaning up

Cover drains. Collect, bind, and pump off spills. Observe possible material restrictions (see sections 7 and 10). Take up carefully. Dispose of properly. Clean up affected area. Avoid generation of dusts.

Reference to other sections

For disposal see section 13.

SECTION 7: Handling and storage

Precautions for safe handling

For precautions see section 2.2.

Conditions for safe storage, including any incompatibilities

Storage conditions

Tightly closed. Dry. Keep in a well-ventilated place. Keep locked up or in an area accessible only to qualified or authorized persons.

Store under inert gas. Air sensitive. hygroscopic

Specific end use(s)

Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection

control parameter

Hazard composition and occupational exposure limits
Does not contain substances with occupational exposure limits.

Exposure controls

Personal protective equipment
Eye/face protection

Use equipment for eye protection tested and approved under appropriate

government standards such as NIOSH (US) or EN 166(EU). Tightly fitting safety goggles

Skin protection

This recommendation applies only to the product stated in the safety data sheet, supplied by us and for the designated use. When dissolving in or mixing with other substances and under conditions deviating from those stated in EN374 please contact the supplier of CE-approved gloves (e.g. KCL GmbH, D-36124 Eichenzell, Internet: www.kcl.de).

Full contact

Material: Nitrile rubber

Minimum layer thickness: 0,11 mm Break through time: 480 min

Material tested:KCL 741 Dermatril? L

Splash contact Material: Nitrile rubber

Minimum layer thickness: 0,11 mm Break through time: 480 min

Material tested:KCL 741 Dermatril? L

Body Protection

protective clothing

Respiratory protection

required when dusts are generated.

Our recommendations on filtering respiratory protection are based on the following standards: DIN EN 143, DIN 14387 and other accompanying standards relating to the used respiratory protection system.

Recommended Filter type: Filter type P3

The entrepeneur has to ensure that maintenance, cleaning and testing of respiratory protective devices are carried out according to the instructions of the producer.

These measures have to be properly documented.

Control of environmental exposure

Do not let product enter drains.

SECTION 9: Physical and chemical properties

Information on basic physicochemical properties

  • Appearance solid
  • Odourammoniacal
  • Odour ThresholdNo data available
  • pH14 at ca.1.000 g/l at 20 °C
  • Melting point/freezing pointMelting point/range: 67 - 70 °C - lit.
  • Initial boiling point and boiling rangeNot applicable
  • Flash pointNot applicable
  • Evaporation rateNo data available
  • Flammability (solid, gas)The product is not flammable. - Flammability (solids)
  • Upper/lower flammability or explosive limits36%
  • Vapour pressure 97 mm Hg ( 20 °C)
  • Vapour density 1.1 (vs air)
  • Relative densityNo data available No data available
  • Water solubility2.200 g/l at 15 °C
  • Partition coefficient: n-octanol/waterlog Pow:< -1,4 at 20 °C - Bioaccumulation is not expected.
  • Autoignition temperatureNo data available
  • Decomposition temperatureNo data available
  • ViscosityViscosity, kinematic: No data available Viscosity, dynamic: No data available
  • Explosive propertiesNo data available
  • Oxidizing propertiesNo data available

Other safety information

No data available

SECTION 10: Stability and reactivity

Reactivity

The following applies in general to flammable organic substances and mixtures: in correspondingly fine distribution, when whirled up a dust explosion potential may generally be assumed.

Chemical stability

The product is chemically stable under standard ambient conditions (room temperature) .

Possibility of hazardous reactions

No data available

Conditions to avoid

Air Avoid moisture.

no information available

Incompatible materials

No data available

Hazardous decomposition products

In the event of fire: see section 5

SECTION 11: Toxicological information

Information on toxicological effects

Acute toxicity
LD50 Oral - Rat - female - 7,5 - 50 mg/kg
(OECD Test Guideline 423) Remarks: (anhydrous substance)
Symptoms: If ingested, severe burns of the mouth and throat, as well as a danger of perforation of the esophagus and the stomach.
Symptoms: mucosal irritations, Cough, Shortness of breath, Possible damages:, damage of respiratory tract, Inhalation may lead to the formation of oedemas in the respiratory tract., Symptoms may be delayed.
LD50 Dermal - Rat - male and female - 12,5 mg/kg (Expert judgment)
Symptoms: Causes severe systemic effects after dermal exposure which could lead to death.
Skin corrosion/irritation
Skin - Rabbit
Result: Corrosive - 4 h (OECD Test Guideline 404)
Remarks: (anhydrous substance)
Serious eye damage/eye irritation
Causes serious eye damage.
Respiratory or skin sensitization
No data available
Germ cell mutagenicity
Test Type: Ames test
Test system: Escherichia coli/Salmonella typhimurium Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 471
Result: negative
Remarks: (anhydrous substance)
Test Type: Mutagenicity (mammal cell test): chromosome aberration. Test system: Chinese hamster lung cells
Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 473
Result: negative
Remarks: (anhydrous substance)
Test Type: In vitro mammalian cell gene mutation test Test system: Mouse lymphoma test
Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 476
Result: negative
Carcinogenicity
No data available
Reproductive toxicity
No data available
Specific target organ toxicity - single exposure
Causes damage to organs. - Central nervous system
Specific target organ toxicity - repeated exposure
Skin contact - Causes damage to organs through prolonged or repeated exposure. - Liver, thymus
Aspiration hazard
No data available

SECTION 12: Ecological information

Toxicity

Toxicity to fish
flow-through test LC50 - Pimephales promelas (fathead minnow) - 462 mg/l - 96 h

(OECD Test Guideline 203)

Remarks: The value is given in analogy to the following substances: tetramethylammonium chloride


Toxicity to daphnia and other aquatic invertebrates

static test EC50 - Daphnia magna (Water flea) - 3 mg/l - 48 h (OECD Test Guideline 202)

Remarks: (anhydrous substance)


Toxicity to algae
static test ErC50 - Pseudokirchneriella subcapitata (green algae) - 96,3 mg/l - 72 h

(OECD Test Guideline 201) Remarks: (anhydrous substance)


static test NOEC - Pseudokirchneriella subcapitata (green algae) - 6,25 mg/l - 72 h

(OECD Test Guideline 201) Remarks: (anhydrous substance)


Toxicity to bacteria
static test EC50 - activated sludge - > 503 mg/l - 3 h (OECD Test Guideline 209)

Persistence and degradability

Biodegradability aerobic - Exposure time 28 d

Result: 100 % - Readily biodegradable. (OECD Test Guideline 301B)

Remarks: (anhydrous substance)


Biochemical Oxygen Demand (BOD)

0,08 mg/g

Bioaccumulative potential

No data available

Mobility in soil

No data available

Results of PBT and vPvB assessment

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

Other adverse effects

Additional ecological information

Discharge into the environment must be avoided.

SECTION 13: Disposal considerations

Waste treatment methods

Product

See www.retrologistik.com for processes regarding the return of chemicals and

containers, or contact us there if you have further questions.

SECTION 14: Transport information

UN number

ADR/RID: 3423 IMDG: 3423 IATA: 3423

UN proper shipping name


ADR/RID: TETRAMETHYLAMMONIUM HYDROXIDE, SOLID IMDG: TETRAMETHYLAMMONIUM HYDROXIDE, SOLID


IATA: Tetramethylammonium hydroxide, solid

14.3

Transport hazard class(es)

ADR/RID: 8 IMDG: 8


IATA: 8

14.4

Packaging group

ADR/RID: II IMDG: II


IATA: II

14.5

Environmental hazards

ADR/RID: no IMDG Marine pollutant: no


IATA: no

14.6

Special precautions for user

No data available


SECTION 15: Regulatory information

Safety, health and environmental regulations/legislation specific for the substance or mixture

Regulations on the Safety Management of Hazardous Chemicals
China Catalog of Hazardous chemicals 2015:Not Listed. website: https://www.mem.gov.cn/
Measures for Environmental Management of New Chemical Substances
European Inventory of Existing Commercial Chemical Substances (EINECS):Not Listed. website: https://echa.europa.eu/
United States Toxic Substances Control Act (TSCA) Inventory:Not Listed. website: https://www.epa.gov/
EC Inventory:Not Listed.
Korea Existing Chemicals List (KECL):Not Listed. website: http://ncis.nier.go.kr
Philippines Inventory of Chemicals and Chemical Substances (PICCS):Listed. website: https://emb.gov.ph/
New Zealand Inventory of Chemicals (NZIoC):Listed. website: https://www.epa.govt.nz/
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC):Listed. website: https://www.mee.gov.cn/
Vietnam National Chemical Inventory:Listed. website: https://chemicaldata.gov.vn/

SECTION 16: Other information

Abbreviations and acronyms

  • CAS: Chemical Abstracts Service
  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • IMDG: International Maritime Dangerous Goods
  • IATA: International Air Transportation Association
  • TWA: Time Weighted Average
  • STEL: Short term exposure limit
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • EC50: Effective Concentration 50%

References

【1】CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple

【2】ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp

【3】ECHA - European Chemicals Agency, website: https://echa.europa.eu/

【4】eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en

【5】ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg

【6】Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp

【7】HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm

【8】IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/

【9】IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home

【10】Sigma-Aldrich, website: https://www.sigmaaldrich.com/

Disclaimer:

The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.

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