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2-fluoro-3-trifluoromethoxy aniline

2-fluoro-3-trifluoromethoxy aniline Structure
  • ₹0
  • Product name: 2-fluoro-3-trifluoromethoxy aniline
  • CAS: 116369-23-4
  • MF: C7H5F4NO
  • MW: 195.11
  • EINECS:
  • MDL Number:MFCD09832254
  • Synonyms:2-fluoro-3-trifluoromethoxy aniline;2-Fluoro-5-(trifluoromethoxy)aniline, JRD, 97%;2-Fluoro-5-(trifluoromethoxy)aniline 99%;3-Amino-alpha,alpha,alpha,4-tetrafluoroanisole;2-Fluoro-5-(trifluoromethoxy);Benzenamine, 2-fluoro-5-(trifluoromethoxy)-;2-Fluoro-5-(trifluoromethoxy)aniline,97%
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Boiling point :190.5±35.0 °C(Predicted)
Density :1.431±0.06 g/cm3(Predicted)
refractive index :1.4485
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
form :liquid
pka :1.97±0.10(Predicted)
color :Clear, colourless
Water Solubility :Insoluble in water.
InChI :InChI=1S/C7H5F4NO/c8-5-2-1-4(3-6(5)12)13-7(9,10)11/h1-3H,12H2
InChIKey :HQUWXEXDIIWBBY-UHFFFAOYSA-N
SMILES :C1(N)=CC(OC(F)(F)F)=CC=C1F

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H311 Toxic in contact with skin Acute toxicity,dermal Category 3 Danger GHS hazard pictograms P280, P302+P352, P312, P322, P361,P363, P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning GHS hazard pictograms P261, P271, P304+P340, P312
Precautionary statements:
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P309 IF exposed or if you feel unwell:
P310 Immediately call a POISON CENTER or doctor/physician.

Description

In discovery of novel benzimidazoles as potent inhibitors of TIE-2 and VEGFR-2 tyrosine kinase receptors 2-Fluoro-5-(trifluoromethoxy)aniline is used as coupling agent. 2-Fluoro-5-(trifluoromethyl)aniline may be used in chemical synthesis studies.

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