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5-Bromo-thiophene-2-carboxylic acid methyl ester

5-Bromo-thiophene-2-carboxylic acid methyl ester Structure
  • ₹0
  • Product name: 5-Bromo-thiophene-2-carboxylic acid methyl ester
  • CAS: 62224-19-5
  • MF: C6H5BrO2S
  • MW: 221.07
  • EINECS:
  • MDL Number:MFCD03233845
  • Synonyms:5-Bromo-thiophene-2-carboxylic acid methyl ester;Methyl 5-bromo-2-thiophenecarboxylate;5-broMo-;Methyl 2-broMothiophene-5...;Methyl 2-broMothiophene-5-carboxylate;2-Thiophenecarboxylic acid, 5-bromo-, methyl ester;methyl 5-bromothiophene-2-carboxylate;5-bromo-2-thiophenecarboxylic acid methyl ester
Manufacturer Product number Product description Packaging Price Updated Buy

Properties

Melting point :87-88℃
Boiling point :251.9±20.0 °C(Predicted)
Density :1.662±0.06 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2–8 °C
Appearance :Off-white to light brown Solid
InChI :InChI=1S/C6H5BrO2S/c1-9-6(8)4-2-3-5(7)10-4/h2-3H,1H3
InChIKey :QLWUHAQCKDHUNL-UHFFFAOYSA-N
SMILES :C1(C(OC)=O)SC(Br)=CC=1

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Methyl 5-Bromo-2-thiophenecarboxylate is used as a reagent in the synthesis of trisubstituted isoxazole derivatives which are novel nonsteroidal antagonists of Farnesoid X Receptor (FXR). FXR plays an important role in regulation of cholesterol, lipid and glucose metabolism.

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