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ChemicalBook >> CAS DataBase List >> (1S,3S,5S)-2-(TERT-BUTOXYCARBONYL)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXYLIC ACID

(1S,3S,5S)-2-(TERT-BUTOXYCARBONYL)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXYLIC ACID

(1S,3S,5S)-2-(TERT-BUTOXYCARBONYL)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXYLIC ACID price.
  • $98 - $10648
  • Product name: (1S,3S,5S)-2-(TERT-BUTOXYCARBONYL)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXYLIC ACID
  • CAS: 197142-36-2
  • MF: C11H17NO4
  • MW: 227.26
  • EINECS:
  • MDL Number:MFCD08691404
  • Synonyms:(1S,3S,5S)-2-(TERT-BUTOXYCARBONYL)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXYLIC ACID;(1s,3s,5s)-2-boc-2-azabicyclo[3.1.0]hexane-3-carboxylic acid;(1S,3S,5S)-N2-BOC-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXYLIC ACID;N-Boc-L-cis-4,5-methanoproline;-2-azabicyclo[3.1.0]hexane-3-carboxylic acid;(3S)-2-[(2-methylpropan-2-yl)oxycarbonyl]-2-azabicyclo[3.1.0]hexane-3-carboxylic acid;(1S,3S,5S)-2-[(2-methylpropan-2-yl)oxycarbonyl]-2-azabicyclo[3.1.0]hexane-3-carboxylic acid;2-Azabicyclo[3.1.0]hexane-2,3-dicarboxylic acid, 2-(1,1-dimethylethyl) ester, (1S,3S,5S)-
17 prices
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Brand
  • ACHEMBLOCK
  • Acrotein
  • Activate Scientific
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • Chemenu
  • Crysdot
  • Matrix Scientific
  • TRC
Package
  • 10mg
  • 100mg
  • 250mg
  • 1G
  • 2.5g
  • 5G
  • 100g
  • ManufacturerACHEMBLOCK
  • Product numberH-8784
  • Product description(1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylicacid 95%
  • Packaging1G
  • Price$500
  • Updated2021-12-16
  • Buy
  • ManufacturerAcrotein
  • Product numberA-7867
  • Product description(1S,3S,5S)-2-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylicacid 97%
  • Packaging1g
  • Price$495
  • Updated2021-12-16
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS59843
  • Product description(1S,3S,5S)-2-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 97% ee
  • Packaging100mg
  • Price$130
  • Updated2021-12-16
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS59843
  • Product description(1S,3S,5S)-2-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 97% ee
  • Packaging250mg
  • Price$266
  • Updated2021-12-16
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS59843
  • Product description(1S,3S,5S)-2-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 97% ee
  • Packaging1g
  • Price$555
  • Updated2021-12-16
  • Buy
  • ManufacturerActivate Scientific
  • Product numberAS59843
  • Product description(1S,3S,5S)-2-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 97% ee
  • Packaging5G
  • Price$1539
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number9735BB
  • Product description(1S,3S,5S)-2-(Tert-butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylicacid
  • Packaging1g
  • Price$879
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number9735BB
  • Product description(1S,3S,5S)-2-(Tert-butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylicacid
  • Packaging2.5g
  • Price$1602
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA604719
  • Product description(1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylicacid 98%
  • Packaging100mg
  • Price$98
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA604719
  • Product description(1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylicacid 98%
  • Packaging250mg
  • Price$148
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA604719
  • Product description(1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylicacid 98%
  • Packaging1g
  • Price$384
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCCH0003936
  • Product description(1S,3S,5S)-2-(TERT-BUTOXYCARBONYL)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXYLIC ACID 95.00%
  • Packaging1G
  • Price$1355.55
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM303771
  • Product description(1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylicacid 97%
  • Packaging100g
  • Price$10648
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11170974
  • Product description(1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylicacid 95+%
  • Packaging1g
  • Price$594
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number133494
  • Product description(1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo-[3.1.0]hexane-3-carboxylicacid 97%
  • Packaging1g
  • Price$990
  • Updated2021-12-16
  • Buy
  • ManufacturerMatrix Scientific
  • Product number133494
  • Product description(1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo-[3.1.0]hexane-3-carboxylicacid 97%
  • Packaging5g
  • Price$3060
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ACHEMBLOCK H-8784 (1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylicacid 95% 1G $500 2021-12-16 Buy
Acrotein A-7867 (1S,3S,5S)-2-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylicacid 97% 1g $495 2021-12-16 Buy
Activate Scientific AS59843 (1S,3S,5S)-2-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 97% ee 100mg $130 2021-12-16 Buy
Activate Scientific AS59843 (1S,3S,5S)-2-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 97% ee 250mg $266 2021-12-16 Buy
Activate Scientific AS59843 (1S,3S,5S)-2-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 97% ee 1g $555 2021-12-16 Buy
Activate Scientific AS59843 (1S,3S,5S)-2-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylic acid 97% ee 5G $1539 2021-12-16 Buy
AK Scientific 9735BB (1S,3S,5S)-2-(Tert-butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylicacid 1g $879 2021-12-16 Buy
AK Scientific 9735BB (1S,3S,5S)-2-(Tert-butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylicacid 2.5g $1602 2021-12-16 Buy
Ambeed A604719 (1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylicacid 98% 100mg $98 2021-12-16 Buy
Ambeed A604719 (1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylicacid 98% 250mg $148 2021-12-16 Buy
Ambeed A604719 (1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylicacid 98% 1g $384 2021-12-16 Buy
American Custom Chemicals Corporation CCH0003936 (1S,3S,5S)-2-(TERT-BUTOXYCARBONYL)-2-AZABICYCLO[3.1.0]HEXANE-3-CARBOXYLIC ACID 95.00% 1G $1355.55 2021-12-16 Buy
Chemenu CM303771 (1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylicacid 97% 100g $10648 2021-12-16 Buy
Crysdot CD11170974 (1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylicacid 95+% 1g $594 2021-12-16 Buy
Matrix Scientific 133494 (1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo-[3.1.0]hexane-3-carboxylicacid 97% 1g $990 2021-12-16 Buy
Matrix Scientific 133494 (1S,3S,5S)-2-(tert-Butoxycarbonyl)-2-azabicyclo-[3.1.0]hexane-3-carboxylicacid 97% 5g $3060 2021-12-16 Buy

Properties

Boiling point :355.9±25.0 °C(Predicted)
Density :1.276±0.06 g/cm3(Predicted)
storage temp. :2-8°C
pka :4.03±0.20(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

(1S,3S,5S)-2-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylic Acid is an impurity of Saxagliptin (S143500), which is a potent and selective reversible inhibitor of dipeptidyl peptidase-4, which is being developed for the treatment of type 2 diabetes. It is absorbed rapidly after oral administration and has a pharmacokinetic profile compatible with once daily dosing.

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