INDOMETHACIN ESTER, N-HEPTYL-
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- $25 - $807
- Product name: INDOMETHACIN ESTER, N-HEPTYL-
- CAS: 282728-47-6
- MF: C26H30ClNO4
- MW: 455.97
- EINECS:
- MDL Number:MFCD03412025
- Synonyms:INDOMETHACIN ESTER, N-HEPTYL-;INDOMETHACIN HEPTYL ESTER;1-(P-CHLOROBENZOYL)-5-METHOXY-3-METHYL-1H-INDOLE-3-ACETIC ACID, N-HEPTYL ESTER;1-(P-CHLOROBENZOYL)-5-METHOXY-2-METHYL-1H-INDOLE-3-ACETIC ACID, N-HEPTYL ESTER;1-(4-CHLOROBENZOYL)-5-METHOXY-2-METHYL-1H-INDOLE-3-ACETIC ACID, 1-HEPTYL ESTER;PYBCHCVNKGZCOH-UHFFFAOYSA-N;1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, heptyl ester
6 prices
Selected condition：
Brand
- AK Scientific
- ApexBio Technology
- Cayman Chemical
Package
- 1mg
- 5mg
- 10mg
- 50mg
- 10mg(solution)
- ManufacturerAK Scientific
- Product number7192CR
- Product descriptionIndomethacinheptylester
- Packaging1mg
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4718
- Product descriptionIndomethacinheptylester
- Packaging10mg(solution)
- Price$210
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number70271
- Product descriptionIndomethacin heptyl ester ≥98%
- Packaging1mg
- Price$25
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number70271
- Product descriptionIndomethacin heptyl ester ≥98%
- Packaging5mg
- Price$107
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number70271
- Product descriptionIndomethacin heptyl ester ≥98%
- Packaging10mg
- Price$186
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number70271
- Product descriptionIndomethacin heptyl ester ≥98%
- Packaging50mg
- Price$807
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 7192CR | Indomethacinheptylester | 1mg | $125 | 2021-12-16 | Buy |
| ApexBio Technology | C4718 | Indomethacinheptylester | 10mg(solution) | $210 | 2021-12-16 | Buy |
| Cayman Chemical | 70271 | Indomethacin heptyl ester ≥98% | 1mg | $25 | 2024-03-01 | Buy |
| Cayman Chemical | 70271 | Indomethacin heptyl ester ≥98% | 5mg | $107 | 2024-03-01 | Buy |
| Cayman Chemical | 70271 | Indomethacin heptyl ester ≥98% | 10mg | $186 | 2024-03-01 | Buy |
| Cayman Chemical | 70271 | Indomethacin heptyl ester ≥98% | 50mg | $807 | 2024-03-01 | Buy |
Properties
Flash point :-16 °C
storage temp. :−20°C
solubility :≤17mg/ml in ethanol;17mg/ml in DMSO;17mg/ml in dimethyl formamide
form :methyl acetate solution
storage temp. :−20°C
solubility :≤17mg/ml in ethanol;17mg/ml in DMSO;17mg/ml in dimethyl formamide
form :methyl acetate solution
Safety Information
| Symbol(GHS): |
 
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Description
Indomethacin is a potent but non-selective inhibitor of both COX-1 and COX-2 in sheep and humans. Structurally, indomethacin is a substituted indole acetic acid, wherein the carboxylate can be derivatized as an ester or amide. These derivatives show enhanced selectivity for the COX-2 isoform. For example, the IC50 for indomethacin heptyl ester for the inhibition of human recombinant COX-2 is 0.04 μM, making it more than 1,700 times more potent as an inhibitor of COX-2 than COX-1. While indomethacin itself has an IC50 of 0.05 μM for the inhibition of COX-2, it also inhibits COX-1 with a corresponding IC50 of 0.67 μM.Suppliers and manufacturers
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