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ChemicalBook >> CAS DataBase List >> (+/-)-12-HYDROXY-5Z,8Z,10E,14Z,17Z-EICOSAPENTAENOIC ACID

(+/-)-12-HYDROXY-5Z,8Z,10E,14Z,17Z-EICOSAPENTAENOIC ACID

(+/-)-12-HYDROXY-5Z,8Z,10E,14Z,17Z-EICOSAPENTAENOIC ACID price.
  • $117 - $2365
  • Product name: (+/-)-12-HYDROXY-5Z,8Z,10E,14Z,17Z-EICOSAPENTAENOIC ACID
  • CAS: 81187-21-5
  • MF: C20H30O3
  • MW: 318.45
  • EINECS:
  • MDL Number:MFCD00065816
  • Synonyms:(+/-)12-HEPE;(+/-)-12-HYDROXY-5Z,8Z,10E,14Z,17Z-EICOSAPENTAENOIC ACID;(5Z,8Z,10E,12S,14Z,17Z)-12-Hydroxy-5,8,10,14,17-icosapentaenoic acid;MCRJLMXYVFDXLS-QGQBRVLBSA-N;5,8,10,14,17-Eicosapentaenoic acid, 12-hydroxy-, (5Z,8Z,10E,14Z,17Z)-;Eicosapentaenoic Acid Impurity 10;(+/-)-12-HYDROXY-5Z,8Z,10E,14Z,17Z-EICOSAPENTAENOIC ACID
Price6 Properties Safety Information Description
6 prices
Selected condition：
Brand
  • AHH
  • Cayman Chemical
  • TRC
Package
  • 25μg
  • 50μg
  • 100μg
  • 250μg
  • 0.00025g
  • 500g
  • ManufacturerAHH
  • Product numberMT-15000
  • Product description(+/-)-12-Hydroxy-5Z,8Z,10E,14Z,17Z-eicosapentaenoic acid 98%
  • Packaging0.00025g
  • Price$538
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number32540
  • Product description(±)12-HEPE ≥98%
  • Packaging25μg
  • Price$117
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number32540
  • Product description(±)12-HEPE ≥98%
  • Packaging50μg
  • Price$222
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number32540
  • Product description(±)12-HEPE ≥98%
  • Packaging100μg
  • Price$418
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number32540
  • Product description(±)12-HEPE ≥98%
  • Packaging250μg
  • Price$923
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberH290015
  • Product description(+/-)12-HEPE
  • Packaging500g
  • Price$2365
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-15000 (+/-)-12-Hydroxy-5Z,8Z,10E,14Z,17Z-eicosapentaenoic acid 98% 0.00025g $538 2021-12-16 Buy
Cayman Chemical 32540 (±)12-HEPE ≥98% 25μg $117 2024-03-01 Buy
Cayman Chemical 32540 (±)12-HEPE ≥98% 50μg $222 2024-03-01 Buy
Cayman Chemical 32540 (±)12-HEPE ≥98% 100μg $418 2024-03-01 Buy
Cayman Chemical 32540 (±)12-HEPE ≥98% 250μg $923 2024-03-01 Buy
TRC H290015 (+/-)12-HEPE 500g $2365 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

(±)12-HEPE is produced by non-enzymatic oxidation of EPA. It contains equal amounts of 12(S)-HEPE and 12(R)-HEPE. The biological activity of (±)12-HEPE is likely mediated by one of the individual isomers, most commonly the 12(S) isomer in mammalian systems. 12-HEPE inhibits platelet aggregation with the same potency as 12-HETE, exhibiting IC50 values of 24 and 25 μM, respectively. These compounds are also equipotent as inhibitors of U46619-induced contraction of rat aorta (IC50s = 8.6-8.8 μM).

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