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ChemicalBook >> CAS DataBase List >> 6-[4-(2-PIPERIDIN-1-YLETHOXY)PHENYL]-3-PYRIDIN-4-YLPYRAZOLO[1,5-A]PYRIMIDINE

6-[4-(2-PIPERIDIN-1-YLETHOXY)PHENYL]-3-PYRIDIN-4-YLPYRAZOLO[1,5-A]PYRIMIDINE

6-[4-(2-PIPERIDIN-1-YLETHOXY)PHENYL]-3-PYRIDIN-4-YLPYRAZOLO[1,5-A]PYRIMIDINE price.
  • $8 - $2000
  • Product name: 6-[4-(2-PIPERIDIN-1-YLETHOXY)PHENYL]-3-PYRIDIN-4-YLPYRAZOLO[1,5-A]PYRIMIDINE
  • CAS: 866405-64-3
  • MF: C24H25N5O
  • MW: 399.49
  • EINECS:
  • MDL Number:MFCD08705402
  • Synonyms:AMPK INHIBITOR;6-[4-(2-PIPERIDIN-1-YLETHOXY)PHENYL]-3-PYRIDIN-4-YLPYRAZOLO[1,5-A]PYRIMIDINE;AMPK Inhibitor, Compound C, Dorsomorphin;6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-pyrazolo[1,5-a]pyrimidinedihydrochloride;Pyrazolo[1,5-a]pyriMidine, 6-[4-[2-(1-piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-;DorsoMorphin, Free Base, >99%;6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrrazolo[1,5-a]pyrimidine;6-[4-[2-(1-piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-pyrazolo[1,5-a]pyrimidine
Price48 Properties Safety Information Description
48 prices
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Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Ark Pharm
  • Biorbyt Ltd
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 50
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number3601AC
  • Product description6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine
  • Packaging50mg
  • Price$460
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA137399
  • Product description6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine 99+%
  • Packaging1mg
  • Price$8
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA137399
  • Product description6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine 99+%
  • Packaging5mg
  • Price$16
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA137399
  • Product description6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine 99+%
  • Packaging10mg
  • Price$24
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA137399
  • Product description6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine 99+%
  • Packaging100mg
  • Price$88
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA137399
  • Product description6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine 99+%
  • Packaging250mg
  • Price$135
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA137399
  • Product description6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine 99+%
  • Packaging1g
  • Price$348
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000516
  • Product descriptionBML-275 95.00%
  • Packaging5MG
  • Price$460
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000516
  • Product descriptionBML-275 95.00%
  • Packaging10MG
  • Price$714.32
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000516
  • Product descriptionBML-275 95.00%
  • Packaging50MG
  • Price$1291.58
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3252
  • Product descriptionDorsomorphin(CompoundC)
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3252
  • Product descriptionDorsomorphin(CompoundC)
  • Packaging10mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3252
  • Product descriptionDorsomorphin(CompoundC)
  • Packaging50mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000329470
  • Product descriptionDorsomorphin 99+%
  • Packaging1mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000329470
  • Product descriptionDorsomorphin 99+%
  • Packaging5mg
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerArk Pharm
  • Product numberP000329470
  • Product descriptionDorsomorphin 99+%
  • Packaging10mg
  • Price$139
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3601AC 6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine 50mg $460 2021-12-16 Buy
Ambeed A137399 6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine 99+% 1mg $8 2021-12-16 Buy
Ambeed A137399 6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine 99+% 5mg $16 2021-12-16 Buy
Ambeed A137399 6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine 99+% 10mg $24 2021-12-16 Buy
Ambeed A137399 6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine 99+% 100mg $88 2021-12-16 Buy
Ambeed A137399 6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine 99+% 250mg $135 2021-12-16 Buy
Ambeed A137399 6-(4-(2-(Piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidine 99+% 1g $348 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000516 BML-275 95.00% 5MG $460 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000516 BML-275 95.00% 10MG $714.32 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000516 BML-275 95.00% 50MG $1291.58 2021-12-16 Buy
ApexBio Technology B3252 Dorsomorphin(CompoundC) 5mg $50 2021-12-16 Buy
ApexBio Technology B3252 Dorsomorphin(CompoundC) 10mg $75 2021-12-16 Buy
ApexBio Technology B3252 Dorsomorphin(CompoundC) 50mg $250 2021-12-16 Buy
Ark Pharm P000329470 Dorsomorphin 99+% 1mg $50 2021-12-16 Buy
Ark Pharm P000329470 Dorsomorphin 99+% 5mg $95 2021-12-16 Buy
Ark Pharm P000329470 Dorsomorphin 99+% 10mg $139 2021-12-16 Buy
Next Last

Properties

Melting point :>228°C(dec.)
Density :1.25±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >2mg/mL (warmed)
pka :8.53±0.10(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.

Description

Dorsomorphin is a potent, reversible inhibitor of AMPK (Ki = 109 nM) that does not exhibit significant activity on structurally related kinases, including ZAPK, SYK, PKCθ, PKA, and JAK3. Dorsomorphin can also dose-dependently inhibit the bone morphogenetic protein type 1 receptors ACTR-I (ALK2), BMPR-IA (ALK3), and BMPR-IB (ALK6). Independent of AMPK inhibition, dorsomorphin at 10 μM has additionally been shown to downregulate the Akt/mTOR pathway to induce autophagy in U251 human glioma cells.

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Suppliers and manufacturers

career henan chemical co
6-[4-(2-PIPERIDIN-1-YLETHOXY)PHENYL]-3-PYRIDIN-4-YLPYRAZOLO[1,5-A]PYRIMIDINE
$1.00 /1KG
6-[4-(2-PIPERIDIN-1-YLETHOXY)PHENYL]-3-PYRIDIN-4-YLPYRAZOLO[1,5-A]PYRIMIDINE CAS:866405-64-3
Capot Chemical Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
Shanghai Zheyan Biotech Co., Ltd.
Biochempartner
BOC Sciences
Chongqing Chemdad Co., Ltd
Alchem Pharmtech,Inc.
CONIER CHEM AND PHARMA LIMITED
Fuxin Pharmaceutical