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ChemicalBook >> CAS DataBase List >> (S)-3-[(S)-2-((S)-1-ETHOXYCARBONYL-3-PHENYL-PROPYLAMINO)-PROPIONYL]-1-METHYL-2-OXO-IMIDAZOLIDINE-4-CARBOXYLIC ACID

(S)-3-[(S)-2-((S)-1-ETHOXYCARBONYL-3-PHENYL-PROPYLAMINO)-PROPIONYL]-1-METHYL-2-OXO-IMIDAZOLIDINE-4-CARBOXYLIC ACID

(S)-3-[(S)-2-((S)-1-ETHOXYCARBONYL-3-PHENYL-PROPYLAMINO)-PROPIONYL]-1-METHYL-2-OXO-IMIDAZOLIDINE-4-CARBOXYLIC ACID price.
  • $36 - $1593.9
  • Product name: (S)-3-[(S)-2-((S)-1-ETHOXYCARBONYL-3-PHENYL-PROPYLAMINO)-PROPIONYL]-1-METHYL-2-OXO-IMIDAZOLIDINE-4-CARBOXYLIC ACID
  • CAS: 89396-94-1
  • MF: C20H27N3O6
  • MW: 405.44488
  • EINECS:685-551-0
  • MDL Number:MFCD00923828
  • Synonyms:(S)-3-[(S)-2-((S)-1-ETHOXYCARBONYL-3-PHENYL-PROPYLAMINO)-PROPIONYL]-1-METHYL-2-OXO-IMIDAZOLIDINE-4-CARBOXYLIC ACID;(S)-3-[(S)-2-((S)-1-ETHOXYCARBONYL-3-PHENYL-PROPYLAMINO)-PROPIONYL]-1-METHYL-2-OXO-IMIDAZOLIDINE-4-CARBOXYLIC ACID: HYDROCHLORIDE;ACE/TA-6366;Novarok;SH-6366;Imidaprilhydrochloride;4-Imidazolidinecarboxylic acid, 3-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-, monohydrochloride, (4S)-;4-Imidazolidinecarboxylic acid, 3-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-oxo-, monohydrochloride, [4S-[3[R*(R*)],4R*]]-
37 prices
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  • Activate Scientific
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • AvaChem
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • CSNpharm
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
Package
  • 10mM(in 1mL DMSO)
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 1g
  • ManufacturerActivate Scientific
  • Product numberAS116975
  • Product descriptionImidapril (hydrochloride) 97+%
  • Packaging250mg
  • Price$655
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberX1042
  • Product descriptionImidapril (hydrochloride)
  • Packaging10mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberX1042
  • Product descriptionImidapril (hydrochloride)
  • Packaging25mg
  • Price$142
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberH37392
  • Product descriptionImidapril (hydrochloride) 98%
  • Packaging250mg
  • Price$144
  • Updated2023-06-20
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberH37392
  • Product descriptionImidapril (hydrochloride) 98%
  • Packaging1g
  • Price$437.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAmbeed
  • Product numberA132165
  • Product description(S)-3-((S)-2-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)-1-methyl-2-oxoimidazolidine-4-carboxylicacidhydrochloride 98+%
  • Packaging10mg
  • Price$91
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA132165
  • Product description(S)-3-((S)-2-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)-1-methyl-2-oxoimidazolidine-4-carboxylicacidhydrochloride 98+%
  • Packaging25mg
  • Price$118
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA132165
  • Product description(S)-3-((S)-2-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)-1-methyl-2-oxoimidazolidine-4-carboxylicacidhydrochloride 98+%
  • Packaging50mg
  • Price$153
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA132165
  • Product description(S)-3-((S)-2-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)-1-methyl-2-oxoimidazolidine-4-carboxylicacidhydrochloride 98+%
  • Packaging100mg
  • Price$198
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0005046
  • Product descriptionIMIDAPRIL HYDROCHLORIDE 95.00%
  • Packaging10MG
  • Price$193.2
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0005046
  • Product descriptionIMIDAPRIL HYDROCHLORIDE 95.00%
  • Packaging100MG
  • Price$1593.9
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8447
  • Product descriptionImidaprilHCl
  • Packaging10mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8447
  • Product descriptionImidaprilHCl
  • Packaging10mM(in 1mL DMSO)
  • Price$66
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA8447
  • Product descriptionImidaprilHCl
  • Packaging50mg
  • Price$155
  • Updated2021-12-16
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  • ManufacturerAvaChem
  • Product number1689
  • Product descriptionImidapril Hydrochloride
  • Packaging10mg
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1689
  • Product descriptionImidapril Hydrochloride
  • Packaging25mg
  • Price$119
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Activate Scientific AS116975 Imidapril (hydrochloride) 97+% 250mg $655 2021-12-16 Buy
AK Scientific X1042 Imidapril (hydrochloride) 10mg $80 2021-12-16 Buy
AK Scientific X1042 Imidapril (hydrochloride) 25mg $142 2021-12-16 Buy
Alfa Aesar H37392 Imidapril (hydrochloride) 98% 250mg $144 2023-06-20 Buy
Alfa Aesar H37392 Imidapril (hydrochloride) 98% 1g $437.65 2024-03-01 Buy
Ambeed A132165 (S)-3-((S)-2-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)-1-methyl-2-oxoimidazolidine-4-carboxylicacidhydrochloride 98+% 10mg $91 2021-12-16 Buy
Ambeed A132165 (S)-3-((S)-2-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)-1-methyl-2-oxoimidazolidine-4-carboxylicacidhydrochloride 98+% 25mg $118 2021-12-16 Buy
Ambeed A132165 (S)-3-((S)-2-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)-1-methyl-2-oxoimidazolidine-4-carboxylicacidhydrochloride 98+% 50mg $153 2021-12-16 Buy
Ambeed A132165 (S)-3-((S)-2-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)-1-methyl-2-oxoimidazolidine-4-carboxylicacidhydrochloride 98+% 100mg $198 2021-12-16 Buy
American Custom Chemicals Corporation API0005046 IMIDAPRIL HYDROCHLORIDE 95.00% 10MG $193.2 2021-12-16 Buy
American Custom Chemicals Corporation API0005046 IMIDAPRIL HYDROCHLORIDE 95.00% 100MG $1593.9 2021-12-16 Buy
ApexBio Technology A8447 ImidaprilHCl 10mg $50 2021-12-16 Buy
ApexBio Technology A8447 ImidaprilHCl 10mM(in 1mL DMSO) $66 2021-12-16 Buy
ApexBio Technology A8447 ImidaprilHCl 50mg $155 2021-12-16 Buy
AvaChem 1689 Imidapril Hydrochloride 10mg $59 2021-12-16 Buy
AvaChem 1689 Imidapril Hydrochloride 25mg $119 2021-12-16 Buy

Properties

Melting point :214-216℃
alpha :D20 -64.1° (c = 0.5 in ethanol)
storage temp. :-20°C
solubility :H2O: ≥5mg/mL
form :powder
color :white to tan
optical activity :[α]/D -50 to -70° in ethanol (c=0.5)
Merck :14,4911

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Imidapril is a prodrug for the active metabolite imidaprilat, an angiotensin-converting enzyme inhibitor that suppresses the conversion of angiotensin I to angiotensin II (IC50 = 2.6 nM), thereby preventing vasoconstriction and decreasing aldosterone secretion by the adrenal cortex. In clinical trials, imidapril was effective at lowering plasma and tissue angiotensin II levels, resulting in peripheral vasodilation, reduced blood pressure, renoprotective effects in patients with type 1 diabetes, and decreased renal sodium and water retention.

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