Avasimibe
|
- $17 - $2250
- Product name: Avasimibe
- CAS: 166518-60-1
- MF: C29H43NO4S
- MW: 501.72
- EINECS:1592732-453-0
- MDL Number:MFCD00934956
- Synonyms:Avasimibe, >=98%;2,6-diisopropylphenyl 2-(2,4,6-triisopropylphenyl)acetylsulfamate;[[2,4,6-tris(1-methylethyl)phenyl]acetyl]-, 2,6-bis(1-methylethyl)phenyl ester] sulfamic acid;PD 148515;avasimibe;n-(2,6-dipropan-2-ylphenoxy)sulfonyl-2-(2,4,6-tripropan-2-ylphenyl)acetamide;N-[(2,6-DIISOPROPYLPHENOXY)SULFONYL]-2-(2,4,6-TRIISOPROPYLPHENYL)ACETAMIDE;((2,4,6-TRIS(1-METHYLETHYL)PHENYL)ACETYL)SULFAMICACID2,6-BIS(1-METHYLETHYL)PHENYLESTER
80 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Arctom
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
Package
- 5
- 1mg
- 5mg
- 10mg
- 25MG
- 50mg
- 10mM*1mLinDMSO
- 100mg
- 10mM*1mLinDMSO(Solution)
- 250mg
- 25
- 200mg
- 500MG
- 1G
- 10mM*1mLinDMSO(Solid+Solvent)
- 50.00g
- 100.00g
- 250.00g
- 10mM(in1mLDMSO)
- Manufactureraablocks
- Product numberAA001WPD
- Product descriptionAvasimibe 99%
- Packaging1mg
- Price$17
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001WPD
- Product descriptionAvasimibe 99%
- Packaging5mg
- Price$21
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001WPD
- Product descriptionAvasimibe 99%
- Packaging10mg
- Price$32
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001WPD
- Product descriptionAvasimibe 99%
- Packaging50mg
- Price$115
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001WPD
- Product descriptionAvasimibe 99%
- Packaging100mg
- Price$205
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA001WPD
- Product descriptionAvasimibe 99
- Packaging200mg
- Price$360
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product number10275
- Product descriptionAvasimibe 98%
- Packaging100MG
- Price$235
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10275
- Product descriptionAvasimibe 98%
- Packaging1G
- Price$1100
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10275
- Product descriptionAvasimibe 98%
- Packaging25MG
- Price$75
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10275
- Product descriptionAvasimibe 98%
- Packaging5MG
- Price$45
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberV2056
- Product descriptionavasimibe
- Packaging50mg
- Price$240
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA156472
- Product descriptionAvasimibe 95+%
- Packaging10mg
- Price$191
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA156472
- Product descriptionAvasimibe 95+%
- Packaging100mg
- Price$418
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA156472
- Product descriptionAvasimibe 95+%
- Packaging50mg
- Price$322
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA156472
- Product descriptionAvasimibe 95+%
- Packaging250mg
- Price$626
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA156472
- Product descriptionAvasimibe 95+%
- Packaging5mg
- Price$147
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA001WPD | Avasimibe 99% | 1mg | $17 | 2026-05-28 | Buy |
| aablocks | AA001WPD | Avasimibe 99% | 5mg | $21 | 2026-05-28 | Buy |
| aablocks | AA001WPD | Avasimibe 99% | 10mg | $32 | 2026-05-28 | Buy |
| aablocks | AA001WPD | Avasimibe 99% | 50mg | $115 | 2026-05-28 | Buy |
| aablocks | AA001WPD | Avasimibe 99% | 100mg | $205 | 2026-05-28 | Buy |
| aablocks | AA001WPD | Avasimibe 99 | 200mg | $360 | 2026-05-28 | Buy |
| ACHEMBLOCK | 10275 | Avasimibe 98% | 100MG | $235 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10275 | Avasimibe 98% | 1G | $1100 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10275 | Avasimibe 98% | 25MG | $75 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10275 | Avasimibe 98% | 5MG | $45 | 2026-05-27 | Buy |
| AK Scientific | V2056 | avasimibe | 50mg | $240 | 2021-12-16 | Buy |
| Ambeed | A156472 | Avasimibe 95+% | 10mg | $191 | 2021-12-16 | Buy |
| Ambeed | A156472 | Avasimibe 95+% | 100mg | $418 | 2021-12-16 | Buy |
| Ambeed | A156472 | Avasimibe 95+% | 50mg | $322 | 2021-12-16 | Buy |
| Ambeed | A156472 | Avasimibe 95+% | 250mg | $626 | 2021-12-16 | Buy |
| Ambeed | A156472 | Avasimibe 95+% | 5mg | $147 | 2021-12-16 | Buy |
Properties
Melting point :178-180° (Lee); mp 169.5-170.4° (Dozeman)
Density :1.072±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: ≥40mg/mL
form :powder
pka :1.97±0.70(Predicted)
color :white to tan
InChI :1S/C29H43NO4S/c1-17(2)22-14-25(20(7)8)27(26(15-22)21(9)10)16-28(31)30-35(32,33)34-29-23(18(3)4)12-11-13-24(29)19(5)6/h11-15,17-21H,16H2,1-10H3,(H,30,31)
InChIKey :PTQXTEKSNBVPQJ-UHFFFAOYSA-N
SMILES :CC(C)c1cc(C(C)C)c(CC(=O)NS(=O)(=O)Oc2c(cccc2C(C)C)C(C)C)c(c1)C(C)C
Density :1.072±0.06 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO: ≥40mg/mL
form :powder
pka :1.97±0.70(Predicted)
color :white to tan
InChI :1S/C29H43NO4S/c1-17(2)22-14-25(20(7)8)27(26(15-22)21(9)10)16-28(31)30-35(32,33)34-29-23(18(3)4)12-11-13-24(29)19(5)6/h11-15,17-21H,16H2,1-10H3,(H,30,31)
InChIKey :PTQXTEKSNBVPQJ-UHFFFAOYSA-N
SMILES :CC(C)c1cc(C(C)C)c(CC(=O)NS(=O)(=O)Oc2c(cccc2C(C)C)C(C)C)c(c1)C(C)C
Safety Information
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Description
Acyl-Coenzyme A:cholesterol acyltransferases (ACAT1 and ACAT2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. Avasimibe is an orally bioavailable inhibitor of ACAT (IC50s = 24 and 9.2 μM for ACAT1 and ACAT2, respectively). It reduces foam cell formation in human macrophages in vitro, enhancing free cholesterol efflux and inhibiting the uptake of modified LDL and dose-dependently reduces plasma total triglyceride and VLDL cholesterol levels in cholesterol-fed animal models. Avasimibe inhibition of ACAT has been used to decrease amyloid β generation in models of Alzheimer’s disease.Related product price
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