SIRT2 Direct Fluorescent Screening Assay Kit
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- $348 - $383
- Product name: SIRT2 Direct Fluorescent Screening Assay Kit
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- Synonyms:SIRT2 Direct Fluorescent Screening Assay Kit
2 prices
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Brand
- Cayman Chemical
Package
- 96Well
- ManufacturerCayman Chemical
- Product number700280
- Product descriptionSIRT2 Direct Fluorescent Screening Assay Kit
- Packaging96Well
- Price$348
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number700280
- Product descriptionSIRT2 Direct Fluorescent Screening Assay Kit
- Packaging96Well
- Price$383
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Cayman Chemical | 700280 | SIRT2 Direct Fluorescent Screening Assay Kit | 96Well | $348 | 2024-03-01 | Buy |
| Cayman Chemical | 700280 | SIRT2 Direct Fluorescent Screening Assay Kit | 96Well | $383 | 2026-04-30 | Buy |
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Description
The sirtuins represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs) that catalyze a reaction coupling lysine deacetylation to the formation of nicotinamide and O-acetyl-ADP-ribose. Cayman’s SIRT2 Direct Fluorescent Screening Assay provides a fluorescence-based method for screening SIRT2 inhibitors or activators. The procedure requires only two easy steps, both performed in the same microplate. In the first step, the substrate, which comprises the p53 sequence Gln-Pro-Lys-Lys(ε-acetyl)-AMC, is incubated with human recombinant SIRT2 along with its cosubstrate NAD+. Deacetylation sensitizes the substrate such that treatment with the Developer in the second step releases a fluorescent product.Needed but not supplied: Please download the kit booklet to verify if UltraPure Water (Milli-Q or equivalent) or any other components are needed for this assay.WARNING This product is not for human or veterinary use.More related product prices