CEP 33779
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- $10 - $4230
- Product name: CEP 33779
- CAS: 1257704-57-6
- MF: C24H26N6O2S
- MW: 462.57
- EINECS:
- MDL Number:MFCD22683932
- Synonyms:[8-(4-Methylsulfonylphenyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl][3-(4-methylpiperazin-1-yl)phenyl]amine;N-[3-(4-Methyl-1-piperazinyl)phenyl]-8-[4-(methylsulfonyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-amine;[1,2,4]Triazolo[1,5-a]pyridin-2-amine, N-[3-(4-methyl-1-piperazinyl)phenyl]-8-[4-(methylsulfonyl)phenyl]-;N-(3-(4-Methylpiperazin-1-yl)phenyl)-8-(4-(methylsulfonyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridi;N-[3-(4-methylpiperazin-1-yl)phenyl]-8-(4-methylsulfonylphenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine;CEP 33779 USP/EP/BP;CS-1066;CEP33779; CEP-33779; CEP 33779.
52 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- ApexBio Technology
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Synthonix
- TRC
- Usbiological
Package
- 1mg
- 10mM*1mLinDMSO
- 500μg
- 5mg
- 10mg
- 25mg
- 50mg
- 10mM(in1mLDMSO)
- 100MG
- 250mg
- 1G
- Manufactureraablocks
- Product numberAA000OM0
- Product descriptionCEP-33779 ≥98%
- Packaging1mg
- Price$10
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000OM0
- Product descriptionCEP-33779 ≥98%
- Packaging5mg
- Price$22
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000OM0
- Product descriptionCEP-33779 ≥98%
- Packaging10mg
- Price$38
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000OM0
- Product descriptionCEP-33779 99%
- Packaging25mg
- Price$79
- Updated2026-05-25
- Buy
- Manufactureraablocks
- Product numberAA000OM0
- Product descriptionCEP-33779 ≥98%
- Packaging50mg
- Price$149
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberM22546
- Product descriptionCEP-33779 98%
- Packaging100MG
- Price$705
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberM22546
- Product descriptionCEP-33779 98%
- Packaging1G
- Price$4230
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberM22546
- Product descriptionCEP-33779 98%
- Packaging1G
- Price$4230
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberM22546
- Product descriptionCEP-33779 98%
- Packaging100MG
- Price$705
- Updated2026-05-25
- Buy
- ManufacturerACHEMBLOCK
- Product numberM22546
- Product descriptionCEP-33779 98%
- Packaging25MG
- Price$305
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberM22546
- Product descriptionCEP-33779 98%
- Packaging25MG
- Price$305
- Updated2026-05-25
- Buy
- ManufacturerAK Scientific
- Product number2311AH
- Product descriptionN-[3-(4-Methyl-1-piperazinyl)phenyl]-8-[4-(methylsulfonyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-amine
- Packaging1g
- Price$1469
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4146
- Product descriptionCEP-33779
- Packaging100mg
- Price$825
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA4146
- Product descriptionCEP-33779
- Packaging50mg
- Price$539
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA4146
- Product descriptionCEP-33779
- Packaging50mg
- Price$770
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4146
- Product descriptionCEP-33779
- Packaging10mg
- Price$230
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA000OM0 | CEP-33779 ≥98% | 1mg | $10 | 2026-05-25 | Buy |
| aablocks | AA000OM0 | CEP-33779 ≥98% | 5mg | $22 | 2026-05-25 | Buy |
| aablocks | AA000OM0 | CEP-33779 ≥98% | 10mg | $38 | 2026-05-25 | Buy |
| aablocks | AA000OM0 | CEP-33779 99% | 25mg | $79 | 2026-05-25 | Buy |
| aablocks | AA000OM0 | CEP-33779 ≥98% | 50mg | $149 | 2026-05-25 | Buy |
| ACHEMBLOCK | M22546 | CEP-33779 98% | 100MG | $705 | 2026-05-27 | Buy |
| ACHEMBLOCK | M22546 | CEP-33779 98% | 1G | $4230 | 2026-05-25 | Buy |
| ACHEMBLOCK | M22546 | CEP-33779 98% | 1G | $4230 | 2026-05-27 | Buy |
| ACHEMBLOCK | M22546 | CEP-33779 98% | 100MG | $705 | 2026-05-25 | Buy |
| ACHEMBLOCK | M22546 | CEP-33779 98% | 25MG | $305 | 2026-05-27 | Buy |
| ACHEMBLOCK | M22546 | CEP-33779 98% | 25MG | $305 | 2026-05-25 | Buy |
| AK Scientific | 2311AH | N-[3-(4-Methyl-1-piperazinyl)phenyl]-8-[4-(methylsulfonyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-amine | 1g | $1469 | 2021-12-16 | Buy |
| ApexBio Technology | A4146 | CEP-33779 | 100mg | $825 | 2026-05-06 | Buy |
| ApexBio Technology | A4146 | CEP-33779 | 50mg | $539 | 2026-05-06 | Buy |
| ApexBio Technology | A4146 | CEP-33779 | 50mg | $770 | 2021-12-16 | Buy |
| ApexBio Technology | A4146 | CEP-33779 | 10mg | $230 | 2021-12-16 | Buy |
Properties
Density :1.35
storage temp. :Store at -20°C
solubility :≥23.15 mg/mL in DMSO with gentle warming; insoluble in EtOH
form :solid
pka :7.78±0.42(Predicted)
color :Light yellow to yellow
storage temp. :Store at -20°C
solubility :≥23.15 mg/mL in DMSO with gentle warming; insoluble in EtOH
form :solid
pka :7.78±0.42(Predicted)
color :Light yellow to yellow
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||
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Description
Janus kinases (JAKs) are non-receptor kinases that mediate signaling through cytokine receptors, often to members of the signal transducer and activator of transcription family. CEP-33779 is a potent, orally available inhibitor of JAK2 (IC50 = 1.3 nM). It shows 65-fold selectivity for JAK2 over JAK3. In mouse models of systemic lupus erythematosus, CEP-33779 reduces the production of inflammatory cytokines, decreases splenomegaly and lymphomegaly, and extends survival. It also diminishes inflammatory signaling and improves clinical scores in mice during collagen antibody-induced arthritis and collagen type II-induced arthritis. CEP-33779 induces regression of established colorectal tumors in mice, reducing angiogenesis and proliferation of tumor cells.Related product price
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