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ChemicalBook >> CAS DataBase List >> E-64C

E-64C

E-64C price.
  • $45 - $1800
  • Product name: E-64C
  • CAS: 76684-89-4
  • MF: C15H26N2O5
  • MW: 314.38
  • EINECS:
  • MDL Number:MFCD00132882
  • Synonyms:(2S,3S)-TRANS-EPOXYSUCCINYL-L-LEUCYLAMIDO-3-METHYLBUTANE;(2S,3S)-L-TRANS-EPOXYSUCCINYL-L-LEUCYLAMIDO-3-METHYLBUTANE;(2S,3S)-3-(((S)-1-(isopentylaMino)-4-Methyl-1-oxopentan-2-yl)carbaMoyl)oxirane-2-carboxylic acid;2-Oxiranecarboxylicacid,3-[[[(1S)-3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-,(2S,3S)-;Loxistatin Acid (E-64C);NSC 694279;E-64c, EP 475;(1S,2S)-2-(((S)-1-(Isopentylamino)-4-methyl-1-oxopentan-2-yl)carbamoyl)cyclopropanecarboxylic
44 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Cayman Chemical
  • Chemenu
  • Chem-Impex
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • TRC
Package
  • 10mM(in 1mL DMSO)
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number2390AH
  • Product descriptionLoxistatinacid
  • Packaging25mg
  • Price$1258
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA602643
  • Product descriptionLoxistatinacid 95+%
  • Packaging1mg
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA602643
  • Product descriptionLoxistatinacid 95+%
  • Packaging5mg
  • Price$193
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA602643
  • Product descriptionLoxistatinacid 95+%
  • Packaging10mg
  • Price$232
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA602643
  • Product descriptionLoxistatinacid 95+%
  • Packaging25mg
  • Price$279
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA602643
  • Product descriptionLoxistatinacid 95+%
  • Packaging50mg
  • Price$335
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA602643
  • Product descriptionLoxistatinacid 95+%
  • Packaging100mg
  • Price$402
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA602643
  • Product descriptionLoxistatinacid 95+%
  • Packaging250mg
  • Price$586
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA602643
  • Product descriptionLoxistatinacid 95+%
  • Packaging1g
  • Price$1465
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0015795
  • Product description[2S,3S]-TRANS-EPOXYSUCCINYL-L-LEUCYLAMIDO-3-METHYLBUTANE 95.00%
  • Packaging1MG
  • Price$220.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0015795
  • Product description[2S,3S]-TRANS-EPOXYSUCCINYL-L-LEUCYLAMIDO-3-METHYLBUTANE 95.00%
  • Packaging5MG
  • Price$826.07
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8162
  • Product descriptionE-64-c
  • Packaging1mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8162
  • Product descriptionE-64-c
  • Packaging5mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8162
  • Product descriptionE-64-c
  • Packaging10mM(in 1mL DMSO)
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8162
  • Product descriptionE-64-c
  • Packaging25mg
  • Price$720
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8162
  • Product descriptionE-64-c
  • Packaging100mg
  • Price$1800
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2390AH Loxistatinacid 25mg $1258 2021-12-16 Buy
Ambeed A602643 Loxistatinacid 95+% 1mg $85 2021-12-16 Buy
Ambeed A602643 Loxistatinacid 95+% 5mg $193 2021-12-16 Buy
Ambeed A602643 Loxistatinacid 95+% 10mg $232 2021-12-16 Buy
Ambeed A602643 Loxistatinacid 95+% 25mg $279 2021-12-16 Buy
Ambeed A602643 Loxistatinacid 95+% 50mg $335 2021-12-16 Buy
Ambeed A602643 Loxistatinacid 95+% 100mg $402 2021-12-16 Buy
Ambeed A602643 Loxistatinacid 95+% 250mg $586 2021-12-16 Buy
Ambeed A602643 Loxistatinacid 95+% 1g $1465 2021-12-16 Buy
American Custom Chemicals Corporation API0015795 [2S,3S]-TRANS-EPOXYSUCCINYL-L-LEUCYLAMIDO-3-METHYLBUTANE 95.00% 1MG $220.5 2021-12-16 Buy
American Custom Chemicals Corporation API0015795 [2S,3S]-TRANS-EPOXYSUCCINYL-L-LEUCYLAMIDO-3-METHYLBUTANE 95.00% 5MG $826.07 2021-12-16 Buy
ApexBio Technology A8162 E-64-c 1mg $45 2021-12-16 Buy
ApexBio Technology A8162 E-64-c 5mg $200 2021-12-16 Buy
ApexBio Technology A8162 E-64-c 10mM(in 1mL DMSO) $200 2021-12-16 Buy
ApexBio Technology A8162 E-64-c 25mg $720 2021-12-16 Buy
ApexBio Technology A8162 E-64-c 100mg $1800 2021-12-16 Buy

Properties

storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :≥31.4 mg/mL in DMSO; insoluble in H2O; ≥111.8 mg/mL in EtOH
form :White to off-white solid
InChIKey :SCMSYZJDIQPSDI-SRVKXCTJSA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

E-64c is an active metabolite of the protease inhibitor E-64d . E-64c inhibits the cysteine proteases cathepsin B, cathepsin H, and papain but not the serine proteases trypsin, chymotrypsin, or elastase. It reduces the autocatalytic activity of the foot-and-mouth-disease virus (FMDV) leader protease when used at concentrations ranging from 0.1 to 1 mg/ml. E-64c reduces infection of HEK293T cells by an HIV-based virus system pseudotyped with severe acute respiratory syndrome coronavirus (SARS-CoV) surface glycoprotein, also known as the spike glycoprotein, in a concentration-dependent manner.

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