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ChemicalBook >> CAS DataBase List >> Esculetin

Esculetin

Esculetin price.
  • $5 - $4741.04
  • Product name: Esculetin
  • CAS: 305-01-1
  • MF: C9H6O4
  • MW: 178.14
  • EINECS:206-161-5
  • MDL Number:MFCD00006874
  • Synonyms:CICHORIGENIN;CICHERINGENIN;ESCULETOL;ESCULETIN;LABOTEST-BB LT00233229;AKOS 215-98;6,7-DIHYDROXY-CHROMEN-2-ONE;2H-1-BENZOPYRAN-2-ONE, 6,7-DIHYDROXY-
Price50 Properties Safety Information Description
50 prices
Selected condition：
Brand
  • AHH
  • AK Scientific
  • Alfa Aesar
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • Chem-Impex
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • SynQuest Laboratories
  • TCI Chemical
  • Usbiological
Package
  • 20mg
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • y0001611
  • 10mM(in 1mL DMSO)
  • 250mg
  • 1g
  • 2g
  • 5g
  • 10g
  • 25g
  • 100G
  • 250G
  • 1kg
  • ManufacturerAHH
  • Product numberMT-09825
  • Product description6,7-Dihydroxycoumarin 98%
  • Packaging25g
  • Price$246
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberD242
  • Product description6,7-Dihydroxycoumarin
  • Packaging5g
  • Price$145
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberA15393
  • Product description6,7-Dihydroxycoumarin, 98+%
  • Packaging1g
  • Price$64.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberA15393
  • Product description6,7-Dihydroxycoumarin, 98+%
  • Packaging5g
  • Price$257.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000258
  • Product descriptionESCULETIN 95.00%
  • Packaging1G
  • Price$157.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000258
  • Product descriptionESCULETIN 95.00%
  • Packaging25G
  • Price$1126.82
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000258
  • Product descriptionESCULETIN 95.00%
  • Packaging100G
  • Price$2673.83
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000258
  • Product descriptionESCULETIN 95.00%
  • Packaging250G
  • Price$4741.04
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN1764
  • Product description6,7-Dihydroxycoumarin
  • Packaging20mg
  • Price$40
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN1764
  • Product description6,7-Dihydroxycoumarin
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS017112
  • Product descriptionEsculetin 98%
  • Packaging100mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS017112
  • Product descriptionEsculetin 98%
  • Packaging250mg
  • Price$7
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS017112
  • Product descriptionEsculetin 98%
  • Packaging1g
  • Price$15
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN99115
  • Product description6,7-Dihydroxycoumarin ≥98%
  • Packaging20mg
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS017112
  • Product descriptionEsculetin 98%
  • Packaging5g
  • Price$40
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS017112
  • Product descriptionEsculetin 98%
  • Packaging10g
  • Price$75
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-09825 6,7-Dihydroxycoumarin 98% 25g $246 2021-12-16 Buy
AK Scientific D242 6,7-Dihydroxycoumarin 5g $145 2021-12-16 Buy
Alfa Aesar A15393 6,7-Dihydroxycoumarin, 98+% 1g $64.65 2024-03-01 Buy
Alfa Aesar A15393 6,7-Dihydroxycoumarin, 98+% 5g $257.65 2024-03-01 Buy
American Custom Chemicals Corporation INB0000258 ESCULETIN 95.00% 1G $157.5 2021-12-16 Buy
American Custom Chemicals Corporation INB0000258 ESCULETIN 95.00% 25G $1126.82 2021-12-16 Buy
American Custom Chemicals Corporation INB0000258 ESCULETIN 95.00% 100G $2673.83 2021-12-16 Buy
American Custom Chemicals Corporation INB0000258 ESCULETIN 95.00% 250G $4741.04 2021-12-16 Buy
ApexBio Technology N1764 6,7-Dihydroxycoumarin 20mg $40 2021-12-16 Buy
ApexBio Technology N1764 6,7-Dihydroxycoumarin 10mM(in 1mL DMSO) $50 2021-12-16 Buy
Arctom AS017112 Esculetin 98% 100mg $5 2021-12-16 Buy
Arctom AS017112 Esculetin 98% 250mg $7 2021-12-16 Buy
Arctom AS017112 Esculetin 98% 1g $15 2021-12-16 Buy
Arctom CFN99115 6,7-Dihydroxycoumarin ≥98% 20mg $30 2021-12-16 Buy
Arctom AS017112 Esculetin 98% 5g $40 2021-12-16 Buy
Arctom AS017112 Esculetin 98% 10g $75 2021-12-16 Buy
Next Last

Properties

Melting point :271-273 °C(lit.)
Boiling point :270.35°C (rough estimate)
Density :1.3431 (rough estimate)
refractive index :1.4500 (estimate)
storage temp. :2-8°C
solubility :Solubility Almost insoluble in boiling water, ether; soluble in hot ethanol, glacial acetic acid
form :powder
pka :1.71(at 25℃)
color :Light yellow
PH Range :Weak blue uorescence (1.5) to strong blue uorescence (2.0)
Water Solubility :slightly soluble
Merck :14,3697
BRN :152788
Major Application :antiinflammatory, Herbicides, cosmetics, teeth whitening agent, antifungal, neurodegenerative andfungal, antibacterial, antiviral, treating drug-induced weight gain, neurodegenerative and blood coagulation disorders, cancer, amyloidosis, skin impairments and baldness
InChIKey :ILEDWLMCKZNDJK-UHFFFAOYSA-N
LogP :0.980 (est)
CAS DataBase Reference :305-01-1(CAS DataBase Reference)
NIST Chemistry Reference :Coumarin, 6,7-dihydroxy-(305-01-1)
EPA Substance Registry System :Esculetin (305-01-1)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Description

In the presence of esculetin and HA14-1 (sc-205911) expression of the death receptor 4 (DR4) has been observed to be upregulated and extracellular-regulated kinase (ERK) to be activated. Other studies suggest that esculetin upregulates death receptor 5 (DR5) protein expression, and enhances TRAIL-induced apoptosis. It also inhibits the activity of 12-LO (12-lipoxygenase), and decreases leukotriene biosynthesis during 5-LO inhibition.

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Suppliers and manufacturers

Shaanxi Haibo Biotechnology Co., Ltd
6,7-Dihydroxycoumarin
$0.00 /25kg
6,7-Dihydroxycoumarin CAS:305-01-1
Henan Fengda Chemical Co., Ltd
Esculetin
$1.00 /1000KG
Esculetin CAS:305-01-1
career henan chemical co
Esculetin
$1.00 /1KG
Esculetin CAS:305-01-1
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd
Capot Chemical Co.,Ltd.
Henan Tianfu Chemical Co.,Ltd.
Hangzhou FandaChem Co.,Ltd.
Shanghai Zheyan Biotech Co., Ltd.
Chengdu Biopurify Phytochemicals Ltd.
Nanjing Dolon Biotechnology Co.,Ltd.