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ChemicalBook >> CAS DataBase List >> 2-Amino-2-methyl-1-propanol

2-Amino-2-methyl-1-propanol

2-Amino-2-methyl-1-propanol price.
  • $29.6 - $679
  • Product name: 2-Amino-2-methyl-1-propanol
  • CAS: 437-38-7
  • MF: C22H28N2O
  • MW: 336.47
  • EINECS:207-113-6
  • MDL Number:MFCD00661055
  • Synonyms:FENTANYL;1-Phenethyl-4-(N-Phenylpropionamido)piperidine;Phentanyl;Propanamide, N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]-;Propionanilide, N-(1-phenethyl-4-piperidyl)-;R 4263;r4263 ;Sentonil
11 prices
Selected condition:
Brand
  • Cayman Chemical
  • Sigma-Aldrich
  • Usbiological
Package
  • 1mg
  • 5mg
  • 1 mL
  • 1 each
  • 1 unit
  • 200 mg
  • ManufacturerCayman Chemical
  • Product number23580
  • Product descriptionFentanyl ≥98%
  • Packaging5mg
  • Price$83
  • Updated2026-04-30
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberY0001509
  • Product descriptionFentanyl for system suitability European Pharmacopoeia (EP) Reference Standard
  • Packaging1 unit
  • Price$208
  • Updated2025-07-31
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberY0001509
  • Product descriptionFentanyl for system suitability European Pharmacopoeia (EP) Reference Standard
  • Packaging1 each
  • Price$223
  • Updated2026-04-30
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberPHR8976
  • Product descriptionFentanyl certified reference material, pharmaceutical secondary standard
  • Packaging200 mg
  • Price$348
  • Updated2026-04-30
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberF-002
  • Product descriptionFentanyl solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
  • Packaging1 mL
  • Price$29.6
  • Updated2026-04-30
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberF-013
  • Product descriptionFentanyl solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
  • Packaging1 mL
  • Price$51.8
  • Updated2026-04-30
  • Buy
  • ManufacturerUsbiological
  • Product number544439
  • Product descriptionFentanyl Purified.
  • Packaging1mg
  • Price$535
  • Updated2026-06-03
  • Buy
  • ManufacturerUsbiological
  • Product number544440
  • Product descriptionFentanyl Purified.
  • Packaging1mg
  • Price$535
  • Updated2026-06-03
  • Buy
  • ManufacturerUsbiological
  • Product number544441
  • Product descriptionFentanyl Purified.
  • Packaging1mg
  • Price$535
  • Updated2026-06-03
  • Buy
  • ManufacturerUsbiological
  • Product number470725
  • Product descriptionFentanyl Purifiedbyionexchangechromatographyfromascites.
  • Packaging1mg
  • Price$602
  • Updated2026-06-03
  • Buy
  • ManufacturerUsbiological
  • Product number470724
  • Product descriptionFentanyl PurifiedbyProteinAaffinitychromatography.
  • Packaging1mg
  • Price$679
  • Updated2026-06-03
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 23580 Fentanyl ≥98% 5mg $83 2026-04-30 Buy
Sigma-Aldrich Y0001509 Fentanyl for system suitability European Pharmacopoeia (EP) Reference Standard 1 unit $208 2025-07-31 Buy
Sigma-Aldrich Y0001509 Fentanyl for system suitability European Pharmacopoeia (EP) Reference Standard 1 each $223 2026-04-30 Buy
Sigma-Aldrich PHR8976 Fentanyl certified reference material, pharmaceutical secondary standard 200 mg $348 2026-04-30 Buy
Sigma-Aldrich F-002 Fentanyl solution 100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant® 1 mL $29.6 2026-04-30 Buy
Sigma-Aldrich F-013 Fentanyl solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant® 1 mL $51.8 2026-04-30 Buy
Usbiological 544439 Fentanyl Purified. 1mg $535 2026-06-03 Buy
Usbiological 544440 Fentanyl Purified. 1mg $535 2026-06-03 Buy
Usbiological 544441 Fentanyl Purified. 1mg $535 2026-06-03 Buy
Usbiological 470725 Fentanyl Purifiedbyionexchangechromatographyfromascites. 1mg $602 2026-06-03 Buy
Usbiological 470724 Fentanyl PurifiedbyProteinAaffinitychromatography. 1mg $679 2026-06-03 Buy

Properties

Melting point :83-84°C
Boiling point :466℃
Density :1.087
refractive index :1.6500 (estimate)
Flash point :186℃
storage temp. :Controlled Substance, -20°C Freezer
solubility :Practically insoluble in water, freely soluble in ethanol (96 per cent) and in methanol
pka :8.4(at 25℃)
form :A crystalline solid
color :Crystals
Water Solubility :0.2g/L(25 ºC)
Henry's Law Constant :1.1×106 mol/(m3Pa) at 25℃, HSDB (2015)
Stability :Hygroscopic
Major Application :pharmaceutical (small molecule)
InChI :1S/C22H28N2O/c1-2-22(25)24(20-11-7-4-8-12-20)21-14-17-23(18-15-21)16-13-19-9-5-3-6-10-19/h3-12,21H,2,13-18H2,1H3
InChIKey :PJMPHNIQZUBGLI-UHFFFAOYSA-N
SMILES :N2(CCC(CC2)N(c3ccccc3)C(=O)CC)CCc1ccccc1
EPA Substance Registry System :Propanamide, N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]- (437-38-7)

Safety Information

Symbol(GHS): Skull and Crossbones (GHS06)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P262 Do not get in eyes, on skin, or on clothing.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Fentanyl is available in a variety of preparations for parenteral, transdermal and transmucosal (including buccal) administration. Because of high firstpass metabolism (~70%) it is not given orally. It is approximately 80–100 times more potent than morphine in the acute seing, although it is approximately 30–40 times as potent when given chronically (e.g. slowrelease transdermal patches). With transdermal administration, the patch and underlying dermis act as a reservoir, and plasma concentration does not reach steady state until approximately 15h after initial application. Plasma concentration also declines slowly after removal (t1/2 ~15–20 h).
Fentanyl is very lipophilic, with a relatively short duration of action. There are several new buccal/transmucosal preparations developed for rapid-onset breakthrough pain. These aim to have a very rapid onset in approximately 10min, although this may not be the case in clinical practice. Fentanyl has a large VD with rapid peripheral tissue uptake, limiting initial hepatic metabolism. This may result in significant variability in plasma concentrations and secondary plasma peaks. It binds to αl-acid glycoprotein and albumin; 40% of the protein-bound fraction is taken up by erythrocytes. The lungs may be important in exerting a first-pass effect on fentanyl (up to 75% of the dose), thus buffering the plasma from high peak drug concentrations.

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