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ChemicalBook >> CAS DataBase List >> Fosaprepitant dimeglumine

Fosaprepitant dimeglumine

Fosaprepitant dimeglumine price.
  • $5 - $4990
  • Product name: Fosaprepitant dimeglumine
  • CAS: 265121-04-8
  • MF: C30H39F7N5O11P
  • MW: 809.63
  • EINECS:682-419-4
  • MDL Number:MFCD23102059
  • Synonyms:Phosphonic acid, (3-(((2R,3S)-2-((1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4-morpholinyl)methyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl)-, compd. with 1-deoxy-1-(methylamino)-D-glucitol (1:2);Unii-D35fm8T64x;[3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-Morpholinyl]Methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonate 1-Deoxy-1-(MethylaMino)-D-glucitol;1-Deoxy-1-(MethylaMino)-D-glucitol [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoroMethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-Morpholinyl]Methyl]-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl]phosphonate;1-DEOXY-1-(METHYLAMINO)-D-GLUCITOL [[(2R,3S]-2-[(1R)-1-[3,5-BIS (TRIFLUOROMETHYL)PHENYL] PHENYL]ETHOXY]-(4-FLUOROPHENYL);3-[2(R)-[1(R)-[3,5-Bis(trifluoroMethyl)phenyl]ethoxy]-3(S)-(4-fluorophenyl)Morpholin-4-ylMethyl]-5-oxo-4,5-dihydro-1H-1,2,4-triazole-1-phosphinic acid bis(N-Methyl-D-glucaMine) salt;Fosaprepitant diMegluMine salt;Fosaprepitant dimeglumine, >=99%
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  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Biosynth Carbosynth
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  • ManufacturerAK Scientific
  • Product numberJ11396
  • Product descriptionFosaprepitantdimeglumine
  • Packaging10mg
  • Price$226
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA455841
  • Product descriptionFosaprepitantdimeglumine 98+%
  • Packaging5mg
  • Price$6
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA455841
  • Product descriptionFosaprepitantdimeglumine 98+%
  • Packaging10mg
  • Price$8
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA455841
  • Product descriptionFosaprepitantdimeglumine 98+%
  • Packaging50mg
  • Price$19
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA455841
  • Product descriptionFosaprepitantdimeglumine 98+%
  • Packaging100mg
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA455841
  • Product descriptionFosaprepitantdimeglumine 98+%
  • Packaging250mg
  • Price$47
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA455841
  • Product descriptionFosaprepitantdimeglumine 98+%
  • Packaging1g
  • Price$126
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA455841
  • Product descriptionFosaprepitantdimeglumine 98+%
  • Packaging5g
  • Price$423
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB2145
  • Product descriptionFosaprepitantdimegluminesalt
  • Packaging50mg
  • Price$485
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS564407
  • Product descriptionFosaprepitantdimeglumine ≥98%
  • Packaging1mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS564407
  • Product descriptionFosaprepitantdimeglumine ≥98%
  • Packaging5mg
  • Price$6
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS564407
  • Product descriptionFosaprepitantdimeglumine ≥98%
  • Packaging10mg
  • Price$8
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS564407
  • Product descriptionFosaprepitantdimeglumine ≥98%
  • Packaging50mg
  • Price$13
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS564407
  • Product descriptionFosaprepitantdimeglumine ≥98%
  • Packaging100mg
  • Price$19
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS564407
  • Product descriptionFosaprepitantdimeglumine ≥98%
  • Packaging250mg
  • Price$35
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS564407
  • Product descriptionFosaprepitantdimeglumine ≥98%
  • Packaging1g
  • Price$91
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J11396 Fosaprepitantdimeglumine 10mg $226 2021-12-16 Buy
Ambeed A455841 Fosaprepitantdimeglumine 98+% 5mg $6 2021-12-16 Buy
Ambeed A455841 Fosaprepitantdimeglumine 98+% 10mg $8 2021-12-16 Buy
Ambeed A455841 Fosaprepitantdimeglumine 98+% 50mg $19 2021-12-16 Buy
Ambeed A455841 Fosaprepitantdimeglumine 98+% 100mg $28 2021-12-16 Buy
Ambeed A455841 Fosaprepitantdimeglumine 98+% 250mg $47 2021-12-16 Buy
Ambeed A455841 Fosaprepitantdimeglumine 98+% 1g $126 2021-12-16 Buy
Ambeed A455841 Fosaprepitantdimeglumine 98+% 5g $423 2021-12-16 Buy
ApexBio Technology B2145 Fosaprepitantdimegluminesalt 50mg $485 2021-12-16 Buy
Arctom AS564407 Fosaprepitantdimeglumine ≥98% 1mg $5 2021-12-16 Buy
Arctom AS564407 Fosaprepitantdimeglumine ≥98% 5mg $6 2021-12-16 Buy
Arctom AS564407 Fosaprepitantdimeglumine ≥98% 10mg $8 2021-12-16 Buy
Arctom AS564407 Fosaprepitantdimeglumine ≥98% 50mg $13 2021-12-16 Buy
Arctom AS564407 Fosaprepitantdimeglumine ≥98% 100mg $19 2021-12-16 Buy
Arctom AS564407 Fosaprepitantdimeglumine ≥98% 250mg $35 2021-12-16 Buy
Arctom AS564407 Fosaprepitantdimeglumine ≥98% 1g $91 2021-12-16 Buy

Properties

storage temp. :Sealed in dry,Store in freezer, under -20°C
solubility :≥50.24 mg/mL in DMSO; insoluble in EtOH; ≥13.16 mg/mL in H2O with ultrasonic
form :Powder
pka :Fosaprepitant dimeglumine has four functional groups which have pKa values of 3.05 ± 0.03, 4.92 ± 0.02, 9.67 ± 0.01 and 10.59 ± 0.03. The pka value of 3.05 corresponds to the morpholinium group, the pka of 4.92 corresponds to the monophosphonate group, the pka of 9.67 corresponds to the meglumine counter ion, and the pka of 10.59 corresponds to the triazolinone NH group.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.

Description

Fosaprepitant dimeglumine is a water-soluble prodrug form of the neurokinin-1 receptor antagonist aprepitant. Formulations containing fosaprepitant dimeglumine have been used to prevent chemotherapy-induced nausea and vomiting.