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ChemicalBook >> CAS DataBase List >> GOSSYPOL

GOSSYPOL

GOSSYPOL price.
  • $60 - $2290
  • Product name: GOSSYPOL
  • CAS: 303-45-7
  • MF: C30H30O8
  • MW: 518.55
  • EINECS:636-899-7
  • MDL Number:MFCD00017352
  • Synonyms:Gossypol from cotton seeds,2,2′-bis(8-Formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene);Thespesin;GOSSYPOL;NSC 624336;NSC 56817;1,1',6,6',7,7'-HEXAHYDROXY-3,3'-DIMETHYL-5,5'-BIS(1-METHYLETHYL)-[2,2'-BINAPHTHALENE]-8,8'-DICARBOXALDEHYDE;2,2'-BIS[8-FORMYL-1,6,7-TRIHYDROXY-5-ISOPROPYL-3-METHYLNAPHTHALENE];2,2'-BIS[8-FORMYL-1,6,7-TRIHYDROXY-5-ISOPROPYL-3-METHYLNAPTHALENE]
39 prices
Selected condition:
Brand
  • AHH
  • Alfa Aesar
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • CSNpharm
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 50
  • 10mg
  • 20mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • 1g
  • 10g
  • 100g
  • ManufacturerAHH
  • Product numberMT-30849
  • Product description2,2-bi[8-Formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene] 95%
  • Packaging1g
  • Price$330
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ63767
  • Product descriptionGossypol, 98+%
  • Packaging100mg
  • Price$212
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ63767
  • Product descriptionGossypol, 98+%
  • Packaging250mg
  • Price$417
  • Updated2024-03-01
  • Buy
  • ManufacturerArctom
  • Product numberCFN90561
  • Product descriptionGossypol ≥98%
  • Packaging20mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS555395
  • Product descriptionGossypol ≥98%
  • Packaging100mg
  • Price$66
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberSY028528
  • Product description1,1’,6,6’,7,7’-Hexahydroxy-5,5’-diisopropyl-3,3’-dimethyl-[2,2’-binaphthalene]-8,8’-dicarbaldehyde
  • Packaging10mg
  • Price$98.18
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS555395
  • Product descriptionGossypol ≥98%
  • Packaging250mg
  • Price$134
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS555395
  • Product descriptionGossypol ≥98%
  • Packaging1g
  • Price$332
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1500
  • Product descriptionGossypol
  • Packaging250mg
  • Price$109
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1500
  • Product descriptionGossypol
  • Packaging1g
  • Price$249
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1500
  • Product descriptionGossypol
  • Packaging10g
  • Price$790
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1500
  • Product descriptionGossypol
  • Packaging100g
  • Price$2290
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb259280
  • Product descriptionGossypol 98%
  • Packaging20mg
  • Price$221
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb259280
  • Product descriptionGossypol 98%
  • Packaging100mg
  • Price$372.3
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb134453
  • Product descriptionGossypol >99%
  • Packaging100mg
  • Price$510
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb134453
  • Product descriptionGossypol >99%
  • Packaging250mg
  • Price$765
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-30849 2,2-bi[8-Formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene] 95% 1g $330 2021-12-16 Buy
Alfa Aesar J63767 Gossypol, 98+% 100mg $212 2024-03-01 Buy
Alfa Aesar J63767 Gossypol, 98+% 250mg $417 2024-03-01 Buy
Arctom CFN90561 Gossypol ≥98% 20mg $60 2021-12-16 Buy
Arctom AS555395 Gossypol ≥98% 100mg $66 2021-12-16 Buy
Arctom SY028528 1,1’,6,6’,7,7’-Hexahydroxy-5,5’-diisopropyl-3,3’-dimethyl-[2,2’-binaphthalene]-8,8’-dicarbaldehyde 10mg $98.18 2021-12-16 Buy
Arctom AS555395 Gossypol ≥98% 250mg $134 2021-12-16 Buy
Arctom AS555395 Gossypol ≥98% 1g $332 2021-12-16 Buy
AvaChem 1500 Gossypol 250mg $109 2021-12-16 Buy
AvaChem 1500 Gossypol 1g $249 2021-12-16 Buy
AvaChem 1500 Gossypol 10g $790 2021-12-16 Buy
AvaChem 1500 Gossypol 100g $2290 2021-12-16 Buy
Biorbyt Ltd orb259280 Gossypol 98% 20mg $221 2021-12-16 Buy
Biorbyt Ltd orb259280 Gossypol 98% 100mg $372.3 2021-12-16 Buy
Biorbyt Ltd orb134453 Gossypol >99% 100mg $510 2021-12-16 Buy
Biorbyt Ltd orb134453 Gossypol >99% 250mg $765 2021-12-16 Buy

Properties

Melting point :181-183 C
Boiling point :522.63°C (rough estimate)
Density :1.1912 (rough estimate)
refractive index :1.4900 (estimate)
storage temp. :2-8°C
solubility :≥25.95 mg/mL in DMSO; insoluble in H2O; ≥2.1 mg/mL in EtOH
form :Off-white to yellow solid.
pka :7.15±0.50(Predicted)
Water Solubility :Soluble in 100%ethanol (25 mg/ml), DMF (25 mg/ml), acetone, DMSO (25 mM), methanol (2 mg/ml), ether, chloroform, sodium carbonate, and dilute aqueous solutions of ammonia . Insoluble in water. Gossypol is a male antifertility agent with antispermatogenic activity and has been shown to contain antitumor, anitviral, and antioxidant properties.
InChIKey :QBKSWRVVCFFDOT-UHFFFAOYSA-N
LogP :5.419 (est)
CAS DataBase Reference :303-45-7
EPA Substance Registry System :[2,2'-Binaphthalene]-8,8'-dicarboxaldehyde, 1,1',6,6',7,7'-hexahydroxy-3,3'-dimethyl-5,5'-bis(1-methylethyl)- (303-45-7)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Gossypol is a racemic mixture of natural polyphenols isolated from parts of the cotton plant (genus Gossypium). It causes infertility in a variety of cotton pests and spermatogenesis arrest in humans. Gossypol also has antimalarial properties, preventing the growth of P. falciparum at low micromolar concentrations. It inhibits aldose reductase (Ki = 0.5 μM). Gossypol also acts as an anticancer agent, inhibiting cell growth in various cancer cell lines, in part by blocking the anti-apoptotic functions of Bcl-2 and Bcl-xL, again at low micromolar concentrations.

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