MITHRAMYCIN A
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- $54 - $6088
- Product name: MITHRAMYCIN A
- CAS: 18378-89-7
- MF: C52H76O24
- MW: 1085.15
- EINECS:634-048-4
- MDL Number:MFCD00135618
- Synonyms:AUREOLIC ACID;METHRAMYCIN A;MITHRAMYCIN A, FOR FLUORESCENCE;MITHRAMYCIN A FROM STREPTOMYCES*PLICATUS APPROX. 96;MITHRAMYCIN COMPLEX FROM STREPTOMYCES*PL ICATUS;MITHRAMYCIN FROM STREPTOMYCES PLICATUS;MITHRACIN;MITHRAMYCIN A
44 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- ApexBio Technology
- Apolloscientific
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- Thermo Scientific Chemicals
- Tocris
- TRC
- Usbiological
Package
- 2mg
- 1
- 10mM*1mLinDMSO(Solution)
- 1mg
- 5mg
- 10mg
- 25MG
- 50mg
- 100mg
- 250mg
- 1ml
- 10mM*1mLinDMSO(Solid+Solvent)
- Manufactureraablocks
- Product numberAA00I1CR
- Product description(2S,3S)-3-((1S,3S,4R)-3,4-Dihydroxy-1-methoxy-2-oxopentyl)-2-(((2S,4R,5R,6R)-4-(((2S,4R,5S,6R)-4-(((2S,4S,5R,6R)-4,5-dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6-(((2S,4R,5R,6R)-4-(((2S,4R,5S,6R)-4,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-8,9-dihydroxy-7-methyl-3,4-dihydroanthracen-1(2H)-one ≥98%
- Packaging1mg
- Price$54
- Updated2026-05-29
- Buy
- Manufactureraablocks
- Product numberAA00I1CR
- Product description(2S,3S)-3-((1S,3S,4R)-3,4-Dihydroxy-1-methoxy-2-oxopentyl)-2-(((2S,4R,5R,6R)-4-(((2S,4R,5S,6R)-4-(((2S,4S,5R,6R)-4,5-dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6-(((2S,4R,5R,6R)-4-(((2S,4R,5S,6R)-4,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-8,9-dihydroxy-7-methyl-3,4-dihydroanthracen-1(2H)-one ≥98%
- Packaging5mg
- Price$209
- Updated2026-05-29
- Buy
- ManufacturerACHEMBLOCK
- Product numberY228507
- Product descriptionMithramycin A 97.00%
- Packaging5MG
- Price$340
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY228507
- Product descriptionMithramycin A 97.00%
- Packaging25MG
- Price$1410
- Updated2026-05-27
- Buy
- ManufacturerApexBio Technology
- Product numberA4546
- Product descriptionMithramycin A
- Packaging5mg
- Price$371
- Updated2026-05-06
- Buy
- ManufacturerApolloscientific
- Product numberBIM1003
- Product descriptionMithramycin A from Streptomyces argillaceus
- Packaging10mg
- Price$380
- Updated2026-06-04
- Buy
- ManufacturerApolloscientific
- Product numberBIM1003
- Product descriptionMithramycin A from Streptomyces argillaceus
- Packaging25mg
- Price$837
- Updated2026-06-04
- Buy
- ManufacturerApolloscientific
- Product numberBIM1003
- Product descriptionMithramycin A from Streptomyces argillaceus
- Packaging5mg
- Price$210
- Updated2026-06-04
- Buy
- ManufacturerApolloscientific
- Product numberBIM1003
- Product descriptionMithramycinAfromStreptomycesargillaceus
- Packaging1mg
- Price$73
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIM1003
- Product descriptionMithramycin A from Streptomyces argillaceus
- Packaging50mg
- Price$1518
- Updated2026-06-04
- Buy
- ManufacturerApolloscientific
- Product numberBIM1003
- Product descriptionMithramycin A from Streptomyces argillaceus
- Packaging100mg
- Price$2754
- Updated2026-06-04
- Buy
- ManufacturerApolloscientific
- Product numberBIM1003
- Product descriptionMithramycin A from Streptomyces argillaceus
- Packaging250mg
- Price$6088
- Updated2026-06-04
- Buy
- ManufacturerArctom
- Product numberHY-A0122
- Product descriptionPlicamycin 99.46%
- Packaging1mg
- Price$174
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-A0122
- Product descriptionPlicamycin 99.46%
- Packaging10mg
- Price$855
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-A0122
- Product descriptionPlicamycin 99.46%
- Packaging10mM*1mLinDMSO(Solid+Solvent)
- Price$1020
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-A0122
- Product descriptionPlicamycin 99.46%
- Packaging10mM*1mLinDMSO(Solution)
- Price$1020
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00I1CR | (2S,3S)-3-((1S,3S,4R)-3,4-Dihydroxy-1-methoxy-2-oxopentyl)-2-(((2S,4R,5R,6R)-4-(((2S,4R,5S,6R)-4-(((2S,4S,5R,6R)-4,5-dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6-(((2S,4R,5R,6R)-4-(((2S,4R,5S,6R)-4,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-8,9-dihydroxy-7-methyl-3,4-dihydroanthracen-1(2H)-one ≥98% | 1mg | $54 | 2026-05-29 | Buy |
| aablocks | AA00I1CR | (2S,3S)-3-((1S,3S,4R)-3,4-Dihydroxy-1-methoxy-2-oxopentyl)-2-(((2S,4R,5R,6R)-4-(((2S,4R,5S,6R)-4-(((2S,4S,5R,6R)-4,5-dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6-(((2S,4R,5R,6R)-4-(((2S,4R,5S,6R)-4,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-8,9-dihydroxy-7-methyl-3,4-dihydroanthracen-1(2H)-one ≥98% | 5mg | $209 | 2026-05-29 | Buy |
| ACHEMBLOCK | Y228507 | Mithramycin A 97.00% | 5MG | $340 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y228507 | Mithramycin A 97.00% | 25MG | $1410 | 2026-05-27 | Buy |
| ApexBio Technology | A4546 | Mithramycin A | 5mg | $371 | 2026-05-06 | Buy |
| Apolloscientific | BIM1003 | Mithramycin A from Streptomyces argillaceus | 10mg | $380 | 2026-06-04 | Buy |
| Apolloscientific | BIM1003 | Mithramycin A from Streptomyces argillaceus | 25mg | $837 | 2026-06-04 | Buy |
| Apolloscientific | BIM1003 | Mithramycin A from Streptomyces argillaceus | 5mg | $210 | 2026-06-04 | Buy |
| Apolloscientific | BIM1003 | MithramycinAfromStreptomycesargillaceus | 1mg | $73 | 2021-12-16 | Buy |
| Apolloscientific | BIM1003 | Mithramycin A from Streptomyces argillaceus | 50mg | $1518 | 2026-06-04 | Buy |
| Apolloscientific | BIM1003 | Mithramycin A from Streptomyces argillaceus | 100mg | $2754 | 2026-06-04 | Buy |
| Apolloscientific | BIM1003 | Mithramycin A from Streptomyces argillaceus | 250mg | $6088 | 2026-06-04 | Buy |
| Arctom | HY-A0122 | Plicamycin 99.46% | 1mg | $174 | 2026-05-26 | Buy |
| Arctom | HY-A0122 | Plicamycin 99.46% | 10mg | $855 | 2026-05-26 | Buy |
| Arctom | HY-A0122 | Plicamycin 99.46% | 10mM*1mLinDMSO(Solid+Solvent) | $1020 | 2026-05-26 | Buy |
| Arctom | HY-A0122 | Plicamycin 99.46% | 10mM*1mLinDMSO(Solution) | $1020 | 2026-05-26 | Buy |
Properties
Melting point :180-183 °C
alpha :D20 -51° (c = 0.4 in ethanol)
Boiling point :761.72°C (rough estimate)
Density :1.1576 (rough estimate)
refractive index :1.6500 (estimate)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 10 mg/ml)
form :Powder
pka :4.54±0.60(Predicted)
color :Red to brown
Merck :13,7619
BRN :5236667
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChIKey :CFCUWKMKBJTWLW-BMKRNREMNA-N
EPA Substance Registry System :Plicamycin (18378-89-7)
alpha :D20 -51° (c = 0.4 in ethanol)
Boiling point :761.72°C (rough estimate)
Density :1.1576 (rough estimate)
refractive index :1.6500 (estimate)
storage temp. :2-8°C
solubility :Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 10 mg/ml)
form :Powder
pka :4.54±0.60(Predicted)
color :Red to brown
Merck :13,7619
BRN :5236667
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChIKey :CFCUWKMKBJTWLW-BMKRNREMNA-N
EPA Substance Registry System :Plicamycin (18378-89-7)
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Mithramycin A is a DNA-binding, anti-tumor and neuroprotective antibiotic originally isolated from S. grieseus that has long been used as a chemotherapeutic agent. It mediates its protective function, in part, by regulating acetylation of histones or transcription factors and, thereby, chromatin accessibility to transcriptional machinery. As a selective Sp1 inhibitor, mithramycin A binds to GC rich DNA sequences, displacing Sp1 transcription factor binding to oncogene promoters, which inhibits their expression. Mithramycin A (at 10-200 nM) can sensitize tumor cells to TRAIL-induced apoptosis and has been used to selectively target tumor cells in many different cancer models.Related product price
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