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ChemicalBook >> CAS DataBase List >> MK8745

MK8745

MK8745 price.
  • $49 - $1200
  • Product name: MK8745
  • CAS: 885325-71-3
  • MF: C20H19ClFN5OS
  • MW: 431.91
  • EINECS:
  • MDL Number:MFCD28009367
  • Synonyms:MK8745;6-[[4-(3-Chloro-2-fluorobenzoyl)piperazin-1-yl]methyl]-N-(thiazol-2-yl)pyridin-2-amine;Methanone, (3-chloro-2-fluorophenyl)[4-[[6-(2-thiazolylamino)-2-pyridinyl]methyl]-1-piperazinyl]-;(3-chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone. MK-8745;(3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanon;CS-1904;MK8745 USP/EP/BP;Inhibitor,inhibit,MK8745,Aurora Kinase,MK-8745,MK 8745,Apoptosis
Price21 Properties Safety Information Description
21 prices
Selected condition：
Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • TRC
Package
  • 10mM(in 1mL DMSO)
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number2550AH
  • Product description(3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone
  • Packaging5mg
  • Price$152
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2550AH
  • Product description(3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone
  • Packaging10mg
  • Price$194
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2550AH
  • Product description(3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone
  • Packaging25mg
  • Price$310
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number2550AH
  • Product description(3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone
  • Packaging50mg
  • Price$415
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8807
  • Product descriptionMK-8745
  • Packaging10mM(in 1mL DMSO)
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8807
  • Product descriptionMK-8745
  • Packaging10mg
  • Price$68
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8807
  • Product descriptionMK-8745
  • Packaging50mg
  • Price$189
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number26190
  • Product descriptionMK-8745
  • Packaging5mg
  • Price$49
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number26190
  • Product descriptionMK-8745
  • Packaging10mg
  • Price$87
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number26190
  • Product descriptionMK-8745
  • Packaging25mg
  • Price$190
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number26190
  • Product descriptionMK-8745
  • Packaging50mg
  • Price$286
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM170040
  • Product description(3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone 98%
  • Packaging100mg
  • Price$230
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5664
  • Product descriptionMK-8745 99.28%
  • Packaging10mg
  • Price$72
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5664
  • Product descriptionMK-8745 99.28%
  • Packaging50mg
  • Price$216
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5664
  • Product descriptionMK-8745 99.28%
  • Packaging100mg
  • Price$396
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000418
  • Product descriptionMK-8745 98+%
  • Packaging10mg
  • Price$50
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2550AH (3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone 5mg $152 2021-12-16 Buy
AK Scientific 2550AH (3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone 10mg $194 2021-12-16 Buy
AK Scientific 2550AH (3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone 25mg $310 2021-12-16 Buy
AK Scientific 2550AH (3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone 50mg $415 2021-12-16 Buy
ApexBio Technology A8807 MK-8745 10mM(in 1mL DMSO) $60 2021-12-16 Buy
ApexBio Technology A8807 MK-8745 10mg $68 2021-12-16 Buy
ApexBio Technology A8807 MK-8745 50mg $189 2021-12-16 Buy
Cayman Chemical 26190 MK-8745 5mg $49 2024-03-01 Buy
Cayman Chemical 26190 MK-8745 10mg $87 2024-03-01 Buy
Cayman Chemical 26190 MK-8745 25mg $190 2024-03-01 Buy
Cayman Chemical 26190 MK-8745 50mg $286 2024-03-01 Buy
Chemenu CM170040 (3-Chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone 98% 100mg $230 2021-12-16 Buy
ChemScene CS-5664 MK-8745 99.28% 10mg $72 2021-12-16 Buy
ChemScene CS-5664 MK-8745 99.28% 50mg $216 2021-12-16 Buy
ChemScene CS-5664 MK-8745 99.28% 100mg $396 2021-12-16 Buy
Crysdot CD31000418 MK-8745 98+% 10mg $50 2021-12-16 Buy
Next Last

Properties

Melting point :177-179°C
Boiling point :605.5±65.0 °C(Predicted)
Density :1.430±0.06 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :DMSO (Slightly), Methanol (Slightly, Heated)
form :Solid
pka :5.20±0.10(Predicted)
color :Off-White

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

MK-8745 is a potent and selective Aurora A kinase inhibitor that induces apoptotic cell death in a p53-dependent manner when tested in vitro in cell lines of multiple lineages.

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