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ChemicalBook >> CAS DataBase List >> ML-180

ML-180

ML-180 price.
  • $18 - $2000
  • Product name: ML-180
  • CAS: 863588-32-3
  • MF: C20H25ClN4O2
  • MW: 388.89
  • EINECS:
  • MDL Number:MFCD05894342
  • Synonyms:ML-180;SR1848;6-[4-(3-chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1H-pyrimidine-2,4-dione;2,4(1H,3H)-Pyrimidinedione, 6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-;6-(4-(3-chlorophenyl)piperazin-1-yl)-3-cyclohexylpyrimidine-2,4(1H,3H)-dione;SR1848 >=98% (HPLC);ML-180 (SR1848);6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexylpyrimidine- ,4(1H,3H)dione
Price52 Properties Safety Information Description
52 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • Ambeed
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • CSNpharm
  • DC Chemicals
Package
  • 002
  • 1mg
  • 2mg
  • 10mg
  • 001
  • 5mg
  • 003
  • 25mg
  • 50mg
  • 100mg
  • 10mM*1mLinDMSO
  • 250mg
  • 1g
  • 1mlx10mM(inDMSO)
  • Manufactureraablocks
  • Product numberAA01EP2N
  • Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione ≥98%
  • Packaging25mg
  • Price$93
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EP2N
  • Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+%
  • Packaging50mg
  • Price$145
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EP2N
  • Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+%
  • Packaging100mg
  • Price$245
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EP2N
  • Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione ≥98%
  • Packaging5mg
  • Price$25
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EP2N
  • Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+%
  • Packaging1mg
  • Price$18
  • Updated2026-05-30
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberU127737
  • Product descriptionML-180 98%
  • Packaging100MG
  • Price$265
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberU127737
  • Product descriptionML-180 98%
  • Packaging25MG
  • Price$100
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product numberSYN5289
  • Product descriptionML180
  • Packaging10mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1210813
  • Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+%
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1210813
  • Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+%
  • Packaging10mg
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1210813
  • Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+%
  • Packaging50mg
  • Price$189
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1210813
  • Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+%
  • Packaging100mg
  • Price$339
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1210813
  • Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+%
  • Packaging250mg
  • Price$633
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA1210813
  • Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+%
  • Packaging1g
  • Price$1629
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb1219596
  • Product descriptionML-180 >98%(HPLC)
  • Packaging100mg
  • Price$770
  • Updated2026-05-06
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb1309410
  • Product descriptionML-180 99.74%
  • Packaging100mg
  • Price$620
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA01EP2N 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione ≥98% 25mg $93 2026-05-30 Buy
aablocks AA01EP2N 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+% 50mg $145 2026-05-30 Buy
aablocks AA01EP2N 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+% 100mg $245 2026-05-30 Buy
aablocks AA01EP2N 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione ≥98% 5mg $25 2026-05-30 Buy
aablocks AA01EP2N 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+% 1mg $18 2026-05-30 Buy
ACHEMBLOCK U127737 ML-180 98% 100MG $265 2026-05-27 Buy
ACHEMBLOCK U127737 ML-180 98% 25MG $100 2026-05-27 Buy
AK Scientific SYN5289 ML180 10mg $160 2021-12-16 Buy
Ambeed A1210813 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+% 5mg $60 2021-12-16 Buy
Ambeed A1210813 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+% 10mg $96 2021-12-16 Buy
Ambeed A1210813 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+% 50mg $189 2021-12-16 Buy
Ambeed A1210813 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+% 100mg $339 2021-12-16 Buy
Ambeed A1210813 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+% 250mg $633 2021-12-16 Buy
Ambeed A1210813 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+% 1g $1629 2021-12-16 Buy
Biorbyt Ltd orb1219596 ML-180 >98%(HPLC) 100mg $770 2026-05-06 Buy
Biorbyt Ltd orb1309410 ML-180 99.74% 100mg $620 2026-05-06 Buy
Next Last

Properties

Density :1.312±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 10 mg/ml
form :A crystalline solid
pka :9.37±0.40(Predicted)
color :Off-white to light yellow
InChI :InChI=1S/C20H25ClN4O2/c21-15-5-4-8-17(13-15)23-9-11-24(12-10-23)18-14-19(26)25(20(27)22-18)16-6-2-1-3-7-16/h4-5,8,13-14,16H,1-3,6-7,9-12H2,(H,22,27)
InChIKey :CHMQQIFPOIZPIJ-UHFFFAOYSA-N
SMILES :C1(=O)NC(N2CCN(C3=CC=CC(Cl)=C3)CC2)=CC(=O)N1C1CCCCC1

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

ML-180 is an inverse agonist of liver receptor homolog-1 (LRH-1, IC50 = 3.7 μM) with maximum efficacy of 64% repression. It is inactive at the related steroidogenic factor-1 transcriptional activator. Through LRH-1, ML-180 alters the expression of haptoglobin and serum amyloid proteins A1 and A4, induces the death of estrogen-receptor negative MDA-MB-231 breast cancer cells, and inhibits the steroidogenic acute regulatory promoter (IC50 = 2.05 μM).

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Suppliers and manufacturers

Jingmo (Xiamen) Biotechnology Co., Ltd BOC Sciences Guangzhou Isun Pharmaceutical Co., Ltd Bide Pharmatech Ltd. Shanghai Lollane Biological Technology Co.,Ltd. Shanghai EFE Biological Technology Co., Ltd. Shanghai YuanYe Biotechnology Co., Ltd. ShangHai Biochempartner Co.,Ltd Shanghai Rechem science Co., Ltd. Shanghai Chaolan Chemical Technology Center