ML-180
|
- $18 - $2000
- Product name: ML-180
- CAS: 863588-32-3
- MF: C20H25ClN4O2
- MW: 388.89
- EINECS:
- MDL Number:MFCD05894342
- Synonyms:ML-180;SR1848;6-[4-(3-chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1H-pyrimidine-2,4-dione;2,4(1H,3H)-Pyrimidinedione, 6-[4-(3-chlorophenyl)-1-piperazinyl]-3-cyclohexyl-;6-(4-(3-chlorophenyl)piperazin-1-yl)-3-cyclohexylpyrimidine-2,4(1H,3H)-dione;SR1848 >=98% (HPLC);ML-180 (SR1848);6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexylpyrimidine- ,4(1H,3H)dione
52 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- CSNpharm
- DC Chemicals
Package
- 2mg
- 001
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 002
- 100mg
- 003
- 10mM*1mLinDMSO
- 250mg
- 1g
- 1mlx10mM(inDMSO)
- Manufactureraablocks
- Product numberAA01EP2N
- Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+%
- Packaging1mg
- Price$18
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EP2N
- Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione ≥98%
- Packaging5mg
- Price$25
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EP2N
- Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione ≥98%
- Packaging25mg
- Price$93
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EP2N
- Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+%
- Packaging50mg
- Price$145
- Updated2026-05-30
- Buy
- Manufactureraablocks
- Product numberAA01EP2N
- Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+%
- Packaging100mg
- Price$245
- Updated2026-05-30
- Buy
- ManufacturerACHEMBLOCK
- Product numberU127737
- Product descriptionML-180 98%
- Packaging100MG
- Price$265
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberU127737
- Product descriptionML-180 98%
- Packaging25MG
- Price$100
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberSYN5289
- Product descriptionML180
- Packaging10mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA1210813
- Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+%
- Packaging10mg
- Price$96
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA1210813
- Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+%
- Packaging50mg
- Price$189
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA1210813
- Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+%
- Packaging100mg
- Price$339
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA1210813
- Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+%
- Packaging5mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA1210813
- Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+%
- Packaging250mg
- Price$633
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA1210813
- Product description6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+%
- Packaging1g
- Price$1629
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1219596
- Product descriptionML-180 >98%(HPLC)
- Packaging100mg
- Price$770
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1309410
- Product descriptionML-180 99.74%
- Packaging100mg
- Price$620
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA01EP2N | 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+% | 1mg | $18 | 2026-05-30 | Buy |
| aablocks | AA01EP2N | 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione ≥98% | 5mg | $25 | 2026-05-30 | Buy |
| aablocks | AA01EP2N | 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione ≥98% | 25mg | $93 | 2026-05-30 | Buy |
| aablocks | AA01EP2N | 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+% | 50mg | $145 | 2026-05-30 | Buy |
| aablocks | AA01EP2N | 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+% | 100mg | $245 | 2026-05-30 | Buy |
| ACHEMBLOCK | U127737 | ML-180 98% | 100MG | $265 | 2026-05-27 | Buy |
| ACHEMBLOCK | U127737 | ML-180 98% | 25MG | $100 | 2026-05-27 | Buy |
| AK Scientific | SYN5289 | ML180 | 10mg | $160 | 2021-12-16 | Buy |
| Ambeed | A1210813 | 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+% | 10mg | $96 | 2021-12-16 | Buy |
| Ambeed | A1210813 | 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+% | 50mg | $189 | 2021-12-16 | Buy |
| Ambeed | A1210813 | 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+% | 100mg | $339 | 2021-12-16 | Buy |
| Ambeed | A1210813 | 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+% | 5mg | $60 | 2021-12-16 | Buy |
| Ambeed | A1210813 | 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+% | 250mg | $633 | 2021-12-16 | Buy |
| Ambeed | A1210813 | 6-[4-(3-Chlorophenyl)piperazin-1-yl]-3-cyclohexyl-1,2,3,4-tetrahydropyrimidine-2,4-dione 98+% | 1g | $1629 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb1219596 | ML-180 >98%(HPLC) | 100mg | $770 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1309410 | ML-180 99.74% | 100mg | $620 | 2026-05-06 | Buy |
Properties
Density :1.312±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 10 mg/ml
form :A crystalline solid
pka :9.37±0.40(Predicted)
color :Off-white to light yellow
InChI :InChI=1S/C20H25ClN4O2/c21-15-5-4-8-17(13-15)23-9-11-24(12-10-23)18-14-19(26)25(20(27)22-18)16-6-2-1-3-7-16/h4-5,8,13-14,16H,1-3,6-7,9-12H2,(H,22,27)
InChIKey :CHMQQIFPOIZPIJ-UHFFFAOYSA-N
SMILES :C1(=O)NC(N2CCN(C3=CC=CC(Cl)=C3)CC2)=CC(=O)N1C1CCCCC1
storage temp. :2-8°C
solubility :DMSO: 10 mg/ml
form :A crystalline solid
pka :9.37±0.40(Predicted)
color :Off-white to light yellow
InChI :InChI=1S/C20H25ClN4O2/c21-15-5-4-8-17(13-15)23-9-11-24(12-10-23)18-14-19(26)25(20(27)22-18)16-6-2-1-3-7-16/h4-5,8,13-14,16H,1-3,6-7,9-12H2,(H,22,27)
InChIKey :CHMQQIFPOIZPIJ-UHFFFAOYSA-N
SMILES :C1(=O)NC(N2CCN(C3=CC=CC(Cl)=C3)CC2)=CC(=O)N1C1CCCCC1
Safety Information
| Symbol(GHS): |
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| Signal word: | Warning | ||||||||||||||
| Hazard statements: |
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| Precautionary statements: |
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Description
ML-180 is an inverse agonist of liver receptor homolog-1 (LRH-1, IC50 = 3.7 μM) with maximum efficacy of 64% repression. It is inactive at the related steroidogenic factor-1 transcriptional activator. Through LRH-1, ML-180 alters the expression of haptoglobin and serum amyloid proteins A1 and A4, induces the death of estrogen-receptor negative MDA-MB-231 breast cancer cells, and inhibits the steroidogenic acute regulatory promoter (IC50 = 2.05 μM).Related product price
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