Welcome to chemicalbook!

010-86108875

18162-48-6 872-50-4 Methylene Chloride naphthalene THF Titanium Dioxide

Structure Search

RFQ

Try our best to find the right business for you.

Messages

Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook >> CAS DataBase List >> MZ 1

MZ 1

$19 - $4350
Product name: MZ 1
CAS: 1797406-69-9
MF: C49H60ClN9O8S2
MW: 1002.64
EINECS:-0
MDL Number:MFCD30742945
Synonyms:MZ 1;(2S,4R)-1-((S)-2-(tert-butyl)-17-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-4,16-dioxo-6,9,12-trioxa-3,15-diazaheptadecanoyl)- 4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide;MZ-1;MZ 1;L-Prolinamide, N-[14-[(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]-1,13-dioxo-3,6,9-trioxa-12-azatetradec-1-yl]-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-;(2S,4R)-N-((S)-2-(tert-Butyl)-17-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-4,16-dioxo-6,9,12-trioxa-3,15-diazaheptadecan-1-oyl)-4-hydroxy-1-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide;cells,MZ-1,protein,Inhibitor,Degrader,PROTACs,Epigenetic Reader Domain,BRD4,selective,degradation,LS174t,MZ 1,MZ1,inhibit;Mz1, selectively degrades BRD4;MZ-1 ，S8889

Price47 Properties Safety Information Description

47 prices

Selected condition：

Brand

aablocks
ACHEMBLOCK
AK Scientific
Ambeed
Apolloscientific
Biorbyt Ltd
Biosynth
Cayman Chemical
ChemScene
DC Chemicals
Sigma-Aldrich
Tocris
TRC

Package

500μg
2.5mg
10mM*1mLinDMSO
1mg
5
5mg
10mg
25mg
50mg
100mg
250mg
500mg
1000mg
1g

Manufactureraablocks
Product numberAA01ENCD
Product descriptionMZ1 98%
Packaging25mg
Price$97
Updated2026-05-30
Buy

Manufactureraablocks
Product numberAA01ENCD
Product descriptionMZ1 98%
Packaging50mg
Price$189
Updated2026-05-30
Buy

Manufactureraablocks
Product numberAA01ENCD
Product descriptionMZ1 98%
Packaging100mg
Price$270
Updated2026-05-30
Buy

Manufactureraablocks
Product numberAA01ENCD
Product descriptionMZ1 98%
Packaging250mg
Price$455
Updated2026-05-30
Buy

Manufactureraablocks
Product numberAA01ENCD
Product descriptionMZ1 97%
Packaging1g
Price$1298
Updated2026-05-30
Buy

Manufactureraablocks
Product numberAA01ENCD
Product descriptionMZ1 98%
Packaging5mg
Price$36
Updated2026-05-30
Buy

Manufactureraablocks
Product numberAA01ENCD
Product descriptionMZ1 98%
Packaging1mg
Price$19
Updated2026-05-30
Buy

ManufacturerACHEMBLOCK
Product numberY225629
Product descriptionMZ 1 97.00%
Packaging50MG
Price$210
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberY225629
Product descriptionMZ 1 97.00%
Packaging100MG
Price$420
Updated2026-05-27
Buy

ManufacturerAK Scientific
Product number1534EH
Product descriptionCID122201421
Packaging5mg
Price$536
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA732871
Product description(2S,4R)-N-((S)-2-(tert-Butyl)-17-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-4,16-dioxo-6,9,12-trioxa-3,15-diazaheptadecan-1-oyl)-4-hydroxy-1-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide 98+%
Packaging100mg
Price$490
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA732871
Product description(2S,4R)-N-((S)-2-(tert-Butyl)-17-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-4,16-dioxo-6,9,12-trioxa-3,15-diazaheptadecan-1-oyl)-4-hydroxy-1-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide 98+%
Packaging25mg
Price$200
Updated2021-12-16
Buy

ManufacturerAmbeed
Product numberA732871
Product description(2S,4R)-N-((S)-2-(tert-Butyl)-17-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-4,16-dioxo-6,9,12-trioxa-3,15-diazaheptadecan-1-oyl)-4-hydroxy-1-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide 98+%
Packaging50mg
Price$305
Updated2021-12-16
Buy

ManufacturerApolloscientific
Product numberBIPC1044
Product descriptionMZ1 98%
Packaging5mg
Price$56
Updated2026-06-04
Buy

ManufacturerApolloscientific
Product numberBIPC1044
Product descriptionMZ1 98%
Packaging25mg
Price$150
Updated2026-06-04
Buy

ManufacturerApolloscientific
Product numberBIPC1044
Product descriptionMZ1 98%
Packaging50mg
Price$293
Updated2026-06-04
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA01ENCD	MZ1 98%	25mg	$97	2026-05-30	Buy
aablocks	AA01ENCD	MZ1 98%	50mg	$189	2026-05-30	Buy
aablocks	AA01ENCD	MZ1 98%	100mg	$270	2026-05-30	Buy
aablocks	AA01ENCD	MZ1 98%	250mg	$455	2026-05-30	Buy
aablocks	AA01ENCD	MZ1 97%	1g	$1298	2026-05-30	Buy
aablocks	AA01ENCD	MZ1 98%	5mg	$36	2026-05-30	Buy
aablocks	AA01ENCD	MZ1 98%	1mg	$19	2026-05-30	Buy
ACHEMBLOCK	Y225629	MZ 1 97.00%	50MG	$210	2026-05-27	Buy
ACHEMBLOCK	Y225629	MZ 1 97.00%	100MG	$420	2026-05-27	Buy
AK Scientific	1534EH	CID122201421	5mg	$536	2021-12-16	Buy
Ambeed	A732871	(2S,4R)-N-((S)-2-(tert-Butyl)-17-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-4,16-dioxo-6,9,12-trioxa-3,15-diazaheptadecan-1-oyl)-4-hydroxy-1-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide 98+%	100mg	$490	2021-12-16	Buy
Ambeed	A732871	(2S,4R)-N-((S)-2-(tert-Butyl)-17-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-4,16-dioxo-6,9,12-trioxa-3,15-diazaheptadecan-1-oyl)-4-hydroxy-1-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide 98+%	25mg	$200	2021-12-16	Buy
Ambeed	A732871	(2S,4R)-N-((S)-2-(tert-Butyl)-17-((S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-4,16-dioxo-6,9,12-trioxa-3,15-diazaheptadecan-1-oyl)-4-hydroxy-1-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide 98+%	50mg	$305	2021-12-16	Buy
Apolloscientific	BIPC1044	MZ1 98%	5mg	$56	2026-06-04	Buy
Apolloscientific	BIPC1044	MZ1 98%	25mg	$150	2026-06-04	Buy
Apolloscientific	BIPC1044	MZ1 98%	50mg	$293	2026-06-04	Buy

Next Last

Properties

Density :1.39±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :Soluble in DMSO:30.0(Max Conc. mg/mL);29.9(Max Conc. mM)
form :A crystalline solid
pka :13.54±0.46(Predicted)
color :White to light yellow
InChIKey :PTAMRJLIOCHJMQ-PYNGZGNASA-N
SMILES :O=C([C@H]1N(C[C@@H](C1)O)C([C@H](C(C)(C)C)NC(COCCOCCOCCNC(C[C@H]2C3=NN=C(N3C4=C(C(C5=CC=C(C=C5)Cl)=N2)C(C)=C(S4)C)C)=O)=O)=O)NCC6=CC=C(C=C6)C7=C(N=CS7)C

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

MZ1 is a hybrid compound that drives the selective proteasomal degradation of bromodomain-containing protein 4 (BRD4). It is characterized as a proteolysis-targeting chimera (PROTAC) and contains JQ-1, which binds bromo- and extra-terminal (BET) proteins, linked to a ligand for the E3 ubiquitin ligase VHL. MZ1 induces the selective degradation of BRD4 in HeLa cells when used at 0.1-0.5 μM. At concentrations of 2-10 μM, MZ1 causes the removal of BRD2, BRD3, and BRD4. BRD protein removal is evident within four hours of adding MZ1 and persists for at least 48 hours, unless MZ1 is removed.

More related product prices

ARV-771 ARV-825 dBET1

Suppliers and manufacturers

TargetMol Chemicals Inc.

$47.00
MZ 1 CAS:1797406-69-9

Wuhan Fortuna Chemical Co., Ltd

MZ 1 CAS:1797406-69-9

BOC Sciences

Career Henan Chemica Co

TargetMol Chemicals Inc.

HANGZHOU LEAP CHEM CO., LTD.

Aladdin Scientific Bide Pharmatech Ltd. Shanghai Lollane Biological Technology Co.,Ltd. Shanghai YuanYe Biotechnology Co., Ltd.

HomePage | About Us | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Product Catalog | Links | Privacy | Terms | Product Manufacturers | New Products
All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.

MZ 1

Properties

Safety Information

Description

Related product price

Suppliers and manufacturers