Milrinone
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- $5 - $1728
- Product name: Milrinone
- CAS: 78415-72-2
- MF: C12H9N3O
- MW: 211.22
- EINECS:278-903-6
- MDL Number:MFCD00133539
- Synonyms:Corotrope;Milrila;3-CYANO-6-METHYL-5-(4-PYRIDYL)-2-PYRIDONE;6-METHYL-5-(4-PYRIDYL)-2-PYRIDONE-3-CARBONITRILE;1,6-DIHYDRO-2-METHYL-6-OXO-(3,4'-BIPYRIDINE)-5-CARBONITRILE;6-Methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carbonitrile;YM-018;2-Oxo-5-(4-pyridyl)-6-methyl-1,2-dihydropyridine-3-carbonitrile
86 prices
Selected condition：
Brand
- aablocks
- Abosyn
- ACHEMBLOCK
- AHH
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- AstaTech
- Atlantic Research Chemicals
- AvaChem
- Axon Medchem
- Biosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TCI Chemical
- Thermo Scientific Chemicals
- Tocris
- TRC
- Usbiological
Package
- 10mM(in1mLDMSO)
- 10mg
- 5mg
- 10mM(in 1mL DMSO)
- 10
- 50mg
- 25MG
- 50
- 100mg
- 250mg
- 500mg
- 0.5g
- 1.00g
- 1g
- 5g
- 25g
- 100g
- 50 mg
- Manufactureraablocks
- Product numberAA003S1Z
- Product description6-methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carbonitrile ≥99%
- Packaging100mg
- Price$10
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003S1Z
- Product description6-methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carbonitrile 99%
- Packaging250mg
- Price$12
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003S1Z
- Product description6-methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carbonitrile 95%
- Packaging1g
- Price$24
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003S1Z
- Product description6-methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carbonitrile 99%
- Packaging5g
- Price$48
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003S1Z
- Product description6-methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carbonitrile ≥99%
- Packaging25g
- Price$221
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA003S1Z
- Product description6-methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carbonitrile 95%
- Packaging100g
- Price$852
- Updated2026-05-28
- Buy
- ManufacturerAbosyn
- Product number61-11777
- Product description2-methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile 95-98%
- Packaging1g
- Price$190
- Updated2021-12-16
- Buy
- ManufacturerAbosyn
- Product number61-11777
- Product description2-methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile 95-98%
- Packaging5g
- Price$590
- Updated2021-12-16
- Buy
- ManufacturerACHEMBLOCK
- Product numberX193192
- Product description1,6-Dihydro-2-methyl-6-oxo-(3,4'-bipyridine)-5-carbonitrile 95.00%
- Packaging25G
- Price$210
- Updated2026-05-27
- Buy
- ManufacturerAHH
- Product numberAPI-1619
- Product descriptionMilrinone 98%
- Packaging0.5g
- Price$795
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberAPI-1619
- Product descriptionMilrinone 97%
- Packaging0.5g
- Price$795
- Updated2026-05-26
- Buy
- ManufacturerAK Scientific
- Product numberD270
- Product descriptionMilrinone
- Packaging5g
- Price$1728
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberD270
- Product descriptionMilrinone
- Packaging500mg
- Price$248
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA218047
- Product description2-Methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile 98+%
- Packaging25g
- Price$208
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA218047
- Product description2-Methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile 98+%
- Packaging100g
- Price$708
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA218047
- Product description2-Methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile 98+%
- Packaging1g
- Price$24
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA003S1Z | 6-methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carbonitrile ≥99% | 100mg | $10 | 2026-05-28 | Buy |
| aablocks | AA003S1Z | 6-methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carbonitrile 99% | 250mg | $12 | 2026-05-28 | Buy |
| aablocks | AA003S1Z | 6-methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carbonitrile 95% | 1g | $24 | 2026-05-28 | Buy |
| aablocks | AA003S1Z | 6-methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carbonitrile 99% | 5g | $48 | 2026-05-28 | Buy |
| aablocks | AA003S1Z | 6-methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carbonitrile ≥99% | 25g | $221 | 2026-05-28 | Buy |
| aablocks | AA003S1Z | 6-methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carbonitrile 95% | 100g | $852 | 2026-05-28 | Buy |
| Abosyn | 61-11777 | 2-methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile 95-98% | 1g | $190 | 2021-12-16 | Buy |
| Abosyn | 61-11777 | 2-methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile 95-98% | 5g | $590 | 2021-12-16 | Buy |
| ACHEMBLOCK | X193192 | 1,6-Dihydro-2-methyl-6-oxo-(3,4'-bipyridine)-5-carbonitrile 95.00% | 25G | $210 | 2026-05-27 | Buy |
| AHH | API-1619 | Milrinone 98% | 0.5g | $795 | 2021-12-16 | Buy |
| AHH | API-1619 | Milrinone 97% | 0.5g | $795 | 2026-05-26 | Buy |
| AK Scientific | D270 | Milrinone | 5g | $1728 | 2021-12-16 | Buy |
| AK Scientific | D270 | Milrinone | 500mg | $248 | 2021-12-16 | Buy |
| Ambeed | A218047 | 2-Methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile 98+% | 25g | $208 | 2021-12-16 | Buy |
| Ambeed | A218047 | 2-Methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile 98+% | 100g | $708 | 2021-12-16 | Buy |
| Ambeed | A218047 | 2-Methyl-6-oxo-1,6-dihydro-[3,4'-bipyridine]-5-carbonitrile 98+% | 1g | $24 | 2021-12-16 | Buy |
Properties
Melting point :>3000C
Boiling point :350.9°C (rough estimate)
Density :1.1922 (rough estimate)
refractive index :1.5700 (estimate)
storage temp. :2-8°C
solubility :DMSO: >10 mg/mL
form :powder
pka :7.21±0.10(Predicted)
color :off-white
Water Solubility :Soluble in DMSO. Insoluble in water.
Merck :14,6197
Stability :Stable. Incompatible with strong oxidizing agents.
InChI :InChI=1S/C12H9N3O/c1-8-11(9-2-4-14-5-3-9)6-10(7-13)12(16)15-8/h2-6H,1H3,(H,15,16)
InChIKey :FYEJSUDMDUIMKJ-UHFFFAOYSA-N
SMILES :C1(C)NC(=O)C(C#N)=CC=1C1C=CN=CC=1
CAS DataBase Reference :78415-72-2(CAS DataBase Reference)
Boiling point :350.9°C (rough estimate)
Density :1.1922 (rough estimate)
refractive index :1.5700 (estimate)
storage temp. :2-8°C
solubility :DMSO: >10 mg/mL
form :powder
pka :7.21±0.10(Predicted)
color :off-white
Water Solubility :Soluble in DMSO. Insoluble in water.
Merck :14,6197
Stability :Stable. Incompatible with strong oxidizing agents.
InChI :InChI=1S/C12H9N3O/c1-8-11(9-2-4-14-5-3-9)6-10(7-13)12(16)15-8/h2-6H,1H3,(H,15,16)
InChIKey :FYEJSUDMDUIMKJ-UHFFFAOYSA-N
SMILES :C1(C)NC(=O)C(C#N)=CC=1C1C=CN=CC=1
CAS DataBase Reference :78415-72-2(CAS DataBase Reference)
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
Phosphodiesterase 3 (PDE3) family members have high-affinities for both cAMP and cGMP and show cGMP-dependent inhibition of cAMP hydrolysis. Milrinone is a potent inhibitor of type 3 phosphodiesterases (PDEs), inhibiting recombinant PDE3A and PDE3B with IC50 values of 0.45 and 1.0 μM, respectively. It less effectively inhibits other PDE isoforms, with IC50 values of 263, >300, 17.5, 49.1, and 58.3 μM for PDE1, PDE2, PDE4, PDE5, and PDE7, respectively. Milrinone has positive inotropic (stimulates cardiac muscle contractions) and vasodilatory effects when administered in vivo.More related product prices
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Suppliers and manufacturers
Beijing Cooperate Pharmaceutical Co.,Ltd
Henan Tianfu Chemical Co.,Ltd.
Shanghai Zheyan Biotech Co., Ltd.
Xiamen AmoyChem Co., Ltd
