Mitomycin C
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- $39 - $3990
- Product name: Mitomycin C
- CAS: 50-07-7
- MF: C15H18N4O5
- MW: 334.33
- EINECS:200-008-6
- MDL Number:MFCD00078109
- Synonyms:Mitomycin C(Ametycine);Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, 6-amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-;Mytomycin C;[1aR-(1aα,8β,8aα,8bα)]-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-α]indole-4,7-dione;6-Amino-1,1a,2,8,8a,8b-hexahydro-8-(hydroxymethyl)-8a-methox-5-methylazirino[2',3':3,4]pyrrolo[1,2-;MitonyycinC;[1aS-(1aα,8β,8aα,8bα)]-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione;8balpha)]-8aalph
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Brand
- Adipogen Life Sciences
- AHH
- AK Scientific
- Alfa Aesar
- ApexBio Technology
- Apolloscientific
- AvaChem
- Biosynth Carbosynth
- BroadPharm
- Cayman Chemical
- Chem-Impex
- DC Chemicals
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 2mg
- 5mg
- 5x2mg
- 10mg
- 10
- 10x2mg
- 25mg
- 50mg
- 50x2mg
- 0.1g
- 500mg
- 1ml
- 10mM(in 1mL DMSO)
- 100mg
- 250mg
- 25G
- 250G
- ManufacturerAdipogen Life Sciences
- Product numberCDX-M0161-M005
- Product descriptionMitomycin C
- Packaging5mg
- Price$47
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberCDX-M0161-M010
- Product descriptionMitomycin C
- Packaging10mg
- Price$82
- Updated2021-12-16
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- ManufacturerAHH
- Product numberMT-54310
- Product descriptionMitomycin 98%
- Packaging0.1g
- Price$310
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberC474
- Product descriptionMitomycin C
- Packaging5mg
- Price$49
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ63193
- Product descriptionMitomycin C
- Packaging10mg
- Price$182
- Updated2023-06-20
- Buy
- ManufacturerAlfa Aesar
- Product numberJ67460
- Product descriptionMitomycin C, 5 mg/ml in DMSO, sterile-filtered
- Packaging1ml
- Price$401
- Updated2023-06-20
- Buy
- ManufacturerApexBio Technology
- Product numberA4452
- Product descriptionMitomycin C
- Packaging5mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4452
- Product descriptionMitomycin C
- Packaging10mM(in 1mL DMSO)
- Price$58
- Updated2021-12-16
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- ManufacturerApexBio Technology
- Product numberA4452
- Product descriptionMitomycin C
- Packaging10mg
- Price$70
- Updated2021-12-16
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- ManufacturerApolloscientific
- Product numberBIM0133
- Product descriptionMitomycin C
- Packaging5mg
- Price$66
- Updated2021-12-16
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- ManufacturerApolloscientific
- Product numberBIM0133
- Product descriptionMitomycin C
- Packaging10mg
- Price$122
- Updated2021-12-16
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- ManufacturerApolloscientific
- Product numberBIM0133
- Product descriptionMitomycin C
- Packaging25mg
- Price$232
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1996
- Product descriptionMitomycin C
- Packaging5mg
- Price$39
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1996
- Product descriptionMitomycin C
- Packaging10mg
- Price$49
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1996
- Product descriptionMitomycin C
- Packaging25mg
- Price$79
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1996
- Product descriptionMitomycin C
- Packaging100mg
- Price$229
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | CDX-M0161-M005 | Mitomycin C | 5mg | $47 | 2021-12-16 | Buy |
| Adipogen Life Sciences | CDX-M0161-M010 | Mitomycin C | 10mg | $82 | 2021-12-16 | Buy |
| AHH | MT-54310 | Mitomycin 98% | 0.1g | $310 | 2021-12-16 | Buy |
| AK Scientific | C474 | Mitomycin C | 5mg | $49 | 2021-12-16 | Buy |
| Alfa Aesar | J63193 | Mitomycin C | 10mg | $182 | 2023-06-20 | Buy |
| Alfa Aesar | J67460 | Mitomycin C, 5 mg/ml in DMSO, sterile-filtered | 1ml | $401 | 2023-06-20 | Buy |
| ApexBio Technology | A4452 | Mitomycin C | 5mg | $50 | 2021-12-16 | Buy |
| ApexBio Technology | A4452 | Mitomycin C | 10mM(in 1mL DMSO) | $58 | 2021-12-16 | Buy |
| ApexBio Technology | A4452 | Mitomycin C | 10mg | $70 | 2021-12-16 | Buy |
| Apolloscientific | BIM0133 | Mitomycin C | 5mg | $66 | 2021-12-16 | Buy |
| Apolloscientific | BIM0133 | Mitomycin C | 10mg | $122 | 2021-12-16 | Buy |
| Apolloscientific | BIM0133 | Mitomycin C | 25mg | $232 | 2021-12-16 | Buy |
| AvaChem | 1996 | Mitomycin C | 5mg | $39 | 2021-12-16 | Buy |
| AvaChem | 1996 | Mitomycin C | 10mg | $49 | 2021-12-16 | Buy |
| AvaChem | 1996 | Mitomycin C | 25mg | $79 | 2021-12-16 | Buy |
| AvaChem | 1996 | Mitomycin C | 100mg | $229 | 2021-12-16 | Buy |
Properties
Melting point :360 °C
Boiling point :471.14°C (rough estimate)
Density :1.2238 (rough estimate)
refractive index :1.6800 (estimate)
storage temp. :2-8°C
solubility :H2O: 4 mL/vial Stock solutions should be filter sterilized and stored at 2-8 °C in the dark., clear to slightly hazy, blue to purple
form :powder
pka :pKa 2.8(H2O,t =25,I=0.1) (Uncertain)
color :blue-gray
PH :pH (0.5 g/l, 25℃ : )5.0～7.0
Water Solubility :soluble
Merck :14,6215
BRN :7231816
Stability :Stable. Incompatible with strong acids, strong bases, strong oxidizing agents.
CAS DataBase Reference :50-07-7(CAS DataBase Reference)
IARC :2B (Vol. 10, Sup 7) 1987
EPA Substance Registry System :Mitomycin C (50-07-7)
Boiling point :471.14°C (rough estimate)
Density :1.2238 (rough estimate)
refractive index :1.6800 (estimate)
storage temp. :2-8°C
solubility :H2O: 4 mL/vial Stock solutions should be filter sterilized and stored at 2-8 °C in the dark., clear to slightly hazy, blue to purple
form :powder
pka :pKa 2.8(H2O,t =25,I=0.1) (Uncertain)
color :blue-gray
PH :pH (0.5 g/l, 25℃ : )5.0～7.0
Water Solubility :soluble
Merck :14,6215
BRN :7231816
Stability :Stable. Incompatible with strong acids, strong bases, strong oxidizing agents.
CAS DataBase Reference :50-07-7(CAS DataBase Reference)
IARC :2B (Vol. 10, Sup 7) 1987
EPA Substance Registry System :Mitomycin C (50-07-7)
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Danger | |||||||||||||||||||||
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Description
Mitomycin C (MMC), an antineoplastic antibiotic derived from Streptomyces caespitosus or Streptomyces lavendulae, is a cell cycle-specific alkylating agent, inhibits DNA synthesis through covalent mitomycin C-DNA adduct with EC50 values of 0.14μM in PC3 cells. Therefore, it was served as a chemotherapeutic agent that has demonstrated its antitumor activity and has been used widely in treatment of various cancers.Although it is active against a wide variety of tumors, newer agents have largely replaced MMC except in anal cancer; outside of the United States, MMC is infrequently used for treatment of advanced non-small cell lung cancer (NSCLC), and breast cancer.
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