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ChemicalBook >> CAS DataBase List >> NCT-503

NCT-503

NCT-503 price.
  • $23 - $2825
  • Product name: NCT-503
  • CAS: 1916571-90-8
  • MF: C20H23F3N4S
  • MW: 408.48
  • EINECS:
  • MDL Number:MFCD30343875
  • Synonyms:NCT-503;9-(6-aminopyridin-3-yl)-1-(4-fluoro-3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one;NCT 503;NCT503;CS-2612;NCT-503; NCT 503; NCT503.;1-Piperazinecarbothioamide, N-(4,6-dimethyl-2-pyridinyl)-4-[[4-(trifluoromethyl)phenyl]methyl]-;NCT-503 >=98% (HPLC);inhibit,NCT-503,NCT503,Inhibitor
Price44 Properties Safety Information Description
44 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
Package
  • 10mM*1mLinDMSO(Solution)
  • 1mg
  • 5mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10mg
  • 10mM*1mLinDMSO
  • 25mg
  • 50mg
  • 100MG
  • 200mg
  • 250MG
  • 500mg
  • 1G
  • Manufactureraablocks
  • Product numberAA01EO2G
  • Product descriptionN-(4,6-Dimethylpyridin-2-yl)-4-(4-(trifluoromethyl)benzyl)piperazine-1-carbothioamide 99%
  • Packaging1mg
  • Price$23
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EO2G
  • Product descriptionN-(4,6-Dimethylpyridin-2-yl)-4-(4-(trifluoromethyl)benzyl)piperazine-1-carbothioamide 99%
  • Packaging5mg
  • Price$42
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EO2G
  • Product descriptionN-(4,6-Dimethylpyridin-2-yl)-4-(4-(trifluoromethyl)benzyl)piperazine-1-carbothioamide 99%
  • Packaging10mg
  • Price$67
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EO2G
  • Product descriptionN-(4,6-Dimethylpyridin-2-yl)-4-(4-(trifluoromethyl)benzyl)piperazine-1-carbothioamide 99%
  • Packaging25mg
  • Price$89
  • Updated2026-05-30
  • Buy
  • Manufactureraablocks
  • Product numberAA01EO2G
  • Product descriptionN-(4,6-Dimethylpyridin-2-yl)-4-(4-(trifluoromethyl)benzyl)piperazine-1-carbothioamide 99%
  • Packaging50mg
  • Price$116
  • Updated2026-05-30
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ65743
  • Product descriptionN-(4,6-dimethylpyridin-2-yl)-4-(4-(trifluoromethyl)benzyl)piperazine-1-carbothioamide 98%
  • Packaging250MG
  • Price$1085
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ65743
  • Product descriptionN-(4,6-dimethylpyridin-2-yl)-4-(4-(trifluoromethyl)benzyl)piperazine-1-carbothioamide 98%
  • Packaging100MG
  • Price$925
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ65743
  • Product descriptionN-(4,6-dimethylpyridin-2-yl)-4-(4-(trifluoromethyl)benzyl)piperazine-1-carbothioamide 98%
  • Packaging1G
  • Price$2825
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number4271EF
  • Product descriptionCID118796328
  • Packaging1mg
  • Price$133
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0004674
  • Product descriptionNCT-503 95.00%
  • Packaging5MG
  • Price$505.55
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3853
  • Product descriptionNCT-503
  • Packaging25mg
  • Price$180
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3853
  • Product descriptionNCT-503
  • Packaging10mg
  • Price$100
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC3853
  • Product descriptionNCT-503
  • Packaging5mg
  • Price$65
  • Updated2026-05-06
  • Buy
  • ManufacturerArctom
  • Product numberHY-101966
  • Product descriptionNCT-503 99.69%
  • Packaging5mg
  • Price$69
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-101966
  • Product descriptionNCT-503 99.69%
  • Packaging10mM*1mLinDMSO(Solid+Solvent)
  • Price$72
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-101966
  • Product descriptionNCT-503 99.69%
  • Packaging10mM*1mLinDMSO(Solution)
  • Price$76
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA01EO2G N-(4,6-Dimethylpyridin-2-yl)-4-(4-(trifluoromethyl)benzyl)piperazine-1-carbothioamide 99% 1mg $23 2026-05-30 Buy
aablocks AA01EO2G N-(4,6-Dimethylpyridin-2-yl)-4-(4-(trifluoromethyl)benzyl)piperazine-1-carbothioamide 99% 5mg $42 2026-05-30 Buy
aablocks AA01EO2G N-(4,6-Dimethylpyridin-2-yl)-4-(4-(trifluoromethyl)benzyl)piperazine-1-carbothioamide 99% 10mg $67 2026-05-30 Buy
aablocks AA01EO2G N-(4,6-Dimethylpyridin-2-yl)-4-(4-(trifluoromethyl)benzyl)piperazine-1-carbothioamide 99% 25mg $89 2026-05-30 Buy
aablocks AA01EO2G N-(4,6-Dimethylpyridin-2-yl)-4-(4-(trifluoromethyl)benzyl)piperazine-1-carbothioamide 99% 50mg $116 2026-05-30 Buy
ACHEMBLOCK Q65743 N-(4,6-dimethylpyridin-2-yl)-4-(4-(trifluoromethyl)benzyl)piperazine-1-carbothioamide 98% 250MG $1085 2026-05-27 Buy
ACHEMBLOCK Q65743 N-(4,6-dimethylpyridin-2-yl)-4-(4-(trifluoromethyl)benzyl)piperazine-1-carbothioamide 98% 100MG $925 2026-05-27 Buy
ACHEMBLOCK Q65743 N-(4,6-dimethylpyridin-2-yl)-4-(4-(trifluoromethyl)benzyl)piperazine-1-carbothioamide 98% 1G $2825 2026-05-27 Buy
AK Scientific 4271EF CID118796328 1mg $133 2021-12-16 Buy
American Custom Chemicals Corporation INB0004674 NCT-503 95.00% 5MG $505.55 2021-12-16 Buy
ApexBio Technology C3853 NCT-503 25mg $180 2026-05-06 Buy
ApexBio Technology C3853 NCT-503 10mg $100 2026-05-06 Buy
ApexBio Technology C3853 NCT-503 5mg $65 2026-05-06 Buy
Arctom HY-101966 NCT-503 99.69% 5mg $69 2026-05-26 Buy
Arctom HY-101966 NCT-503 99.69% 10mM*1mLinDMSO(Solid+Solvent) $72 2026-05-26 Buy
Arctom HY-101966 NCT-503 99.69% 10mM*1mLinDMSO(Solution) $76 2026-05-26 Buy
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Properties

Boiling point :474.3±55.0 °C(Predicted)
Density :1.306±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :≥40.9 mg/mL in DMSO; insoluble in H2O; ≥20.33 mg/mL in EtOH
form :powder
pka :12.99±0.20(Predicted)
color :white to beige
InChI :InChI=1S/C20H23F3N4S/c1-14-11-15(2)24-18(12-14)25-19(28)27-9-7-26(8-10-27)13-16-3-5-17(6-4-16)20(21,22)23/h3-6,11-12H,7-10,13H2,1-2H3,(H,24,25,28)
InChIKey :PJNSZIQUFLWRLH-UHFFFAOYSA-N
SMILES :N1(C(NC2=NC(C)=CC(C)=C2)=S)CCN(CC2=CC=C(C(F)(F)F)C=C2)CC1

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

NCT-503 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells with an IC50 value of 2.5 μM. It has been shown to reduce the production of glucose-derived serine in cells and to suppress the growth of PHGDH-dependent MDA-MB-468 cancer cells both in vitro and in mice bearing orthotopic xenograft tumors.

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NCT-502 NCT-501 NCT-501 (hydrochloride)

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Suppliers and manufacturers

MQ (shanghai) Pharmaceuticals Co., Ltd. Shanghai Beckham Medical Technology Co., Ltd Henan Inokai New Materials Co., Ltd Shanghai Boyle Chemical Co., Ltd. Dalian Meilun Biotech Co., Ltd. MedChemexpress LLC Bide Pharmatech Ltd. Sigma-Aldrich Shanghai Lollane Biological Technology Co.,Ltd. YouCoChem (Beijing) Chemical Technology Co., Ltd.