Olodaterol
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- $56 - $1700
- Product name: Olodaterol
- CAS: 868049-49-4
- MF: C21H26N2O5
- MW: 386.44
- EINECS:813-858-3
- MDL Number:MFCD16619349
- Synonyms:6-Hydroxy-8-[(1R)-1-hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino]ethyl]-2H-1,4-benzoxazin-3(4H)-one;2H-1,4-Benzoxazin-3(4H)-one, 6-hydroxy-8-[(1R)-1-hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino]ethyl]-;BI 1744(Olodaterol;Striverdi Respimat);Olodaterol;Olodaterol ImpurityＡ ;BI-1744;Striverdi
14 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- DC Chemicals
Package
- 1mg
- 2mg
- 5MG
- 10mg
- 25mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number4736BB
- Product descriptionOlodaterol
- Packaging2mg
- Price$171
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0014046
- Product descriptionOLODATEROL 95.00%
- Packaging5MG
- Price$501.28
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFH152793
- Product descriptionOlodaterol
- Packaging1mg
- Price$56
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFH152793
- Product descriptionOlodaterol
- Packaging2mg
- Price$90
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFH152793
- Product descriptionOlodaterol
- Packaging5mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFH152793
- Product descriptionOlodaterol
- Packaging10mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFH152793
- Product descriptionOlodaterol
- Packaging25mg
- Price$325
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number21794
- Product descriptionOlodaterol ≥98%
- Packaging1mg
- Price$89
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21794
- Product descriptionOlodaterol ≥98%
- Packaging5mg
- Price$289
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21794
- Product descriptionOlodaterol ≥98%
- Packaging10mg
- Price$490
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number21794
- Product descriptionOlodaterol ≥98%
- Packaging25mg
- Price$1113
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM255429
- Product description(R)-6-Hydroxy-8-(1-hydroxy-2-((1-(4-methoxyphenyl)-2-methylpropan-2-yl)amino)ethyl)-2H-benzo[b][1,4]oxazin-3(4H)-one 95%
- Packaging100mg
- Price$673
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC10384
- Product descriptionOlodaterol >98%
- Packaging250mg
- Price$850
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC10384
- Product descriptionOlodaterol >98%
- Packaging1g
- Price$1700
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 4736BB | Olodaterol | 2mg | $171 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0014046 | OLODATEROL 95.00% | 5MG | $501.28 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FH152793 | Olodaterol | 1mg | $56 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FH152793 | Olodaterol | 2mg | $90 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FH152793 | Olodaterol | 5mg | $160 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FH152793 | Olodaterol | 10mg | $250 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FH152793 | Olodaterol | 25mg | $325 | 2021-12-16 | Buy |
| Cayman Chemical | 21794 | Olodaterol ≥98% | 1mg | $89 | 2024-03-01 | Buy |
| Cayman Chemical | 21794 | Olodaterol ≥98% | 5mg | $289 | 2024-03-01 | Buy |
| Cayman Chemical | 21794 | Olodaterol ≥98% | 10mg | $490 | 2024-03-01 | Buy |
| Cayman Chemical | 21794 | Olodaterol ≥98% | 25mg | $1113 | 2024-03-01 | Buy |
| Chemenu | CM255429 | (R)-6-Hydroxy-8-(1-hydroxy-2-((1-(4-methoxyphenyl)-2-methylpropan-2-yl)amino)ethyl)-2H-benzo[b][1,4]oxazin-3(4H)-one 95% | 100mg | $673 | 2021-12-16 | Buy |
| DC Chemicals | DC10384 | Olodaterol >98% | 250mg | $850 | 2021-12-16 | Buy |
| DC Chemicals | DC10384 | Olodaterol >98% | 1g | $1700 | 2021-12-16 | Buy |
Properties
Boiling point :649.0±55.0 °C(Predicted)
Density :1.250
solubility :DMF: 20 mg/ml; DMF:PBS (pH 7.2) (1:3): 0.25 mg/ml; DMSO: 15 mg/ml; Ethanol: 1 mg/ml
form :A crystalline solid
pka :9.42±0.20(Predicted)
Stability :Hygroscopic
Density :1.250
solubility :DMF: 20 mg/ml; DMF:PBS (pH 7.2) (1:3): 0.25 mg/ml; DMSO: 15 mg/ml; Ethanol: 1 mg/ml
form :A crystalline solid
pka :9.42±0.20(Predicted)
Stability :Hygroscopic
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Danger | ||||||||||||||||||||||||||||
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Description
In 2013, olodaterol (also known BI-1744 CL) was approved for the treatment of chronic obstructive pulmonary disease (COPD) in Russia (March), Canada (June), and the EuropeanUnion (October). Olodaterol is delivered via the Respimat? Soft Mist? inhaler. Olodaterol was discovered from an effort to identify a β2-adrenergic receptor agonist that could be given once daily and with a superior safety profile over known β2- adrenergic receptor agonists. Olodaterol is a potent β2 agonist (EC50=0.1 nM, intrinsic activity=88%) and is highly selective for the β2 receptor over β1 and β3 receptors. In preclinical models in guinea pigs and dogs, olodaterol had a rapid onset of action and provided bronchoprotection over 24 h. Mechanistic studies indicated that olodaterol forms a highly stable complex with the β2-adrenergic receptor, with a dissociation half-life of 17.8 h. The synthesis of olodaterol proceeds through an (R)-styrene epoxide that is prepared via enantioselective reduction of an α-chloroketone intermediate. Ring opening of the epoxide with 1-(4- methoxyphenyl)-2-methylpropan-2-amine provides olodaterol.Related product price
Suppliers and manufacturers
Shanghai Daken Advanced Materials Co.,Ltd
ATK CHEMICAL COMPANY LIMITED
Anhui Dexinjia Biopharm Co., Ltd
BOC Sciences
Chongqing Chemdad Co., Ltd
Fuxin Pharmaceutical
Neostar United (Changzhou) Industrial Co., Ltd.
Hebei Miaobian Biotechnology Co., Ltd
![6-Hydroxy-8-[(1R)-1-hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino]ethyl]-2H-1,4-benzoxazin-3(4H)-one](https://img.chemicalbook.com/ProductImageEN/2018-8/small/c51f4c59-96fa-40dd-a252-3b57ac0444c0.gif){kind=small}