RADICICOL
|
- $32 - $835
- Product name: RADICICOL
- CAS: 12772-57-5
- MF: C18H17ClO6
- MW: 364.78
- EINECS:
- MDL Number:MFCD06795865
- Synonyms:(1AR,2Z,4E,14R,15AR)-8-CHLORO-1A,14,15,15A-TETRAHYDRO-9,11-DIHYDROXY-14-METHYL-6H-OXIRENO[E][2]BENZOXACYCLOTETRADECIN-6,12(7H)-DIONE;[1AS-(1AR*,2Z,4E,14*,15AR*)]-8-CHLORO-1A,14,15,15A-TETRAHYDRO-9,11-DIHYDROXY-14-METHYL-6H-OXIRENO[E][2]BENZOXACYCLOTETRADECIN-6,12(7H)-DIONE;5-CHLORO-6-(7,8-EPOXY-10-HYDROXY-2-OXO-3,5-UNDECADIENYL)-BETA-RESORCYLIC ACID MU-LACTONE;FO-4910;KF58332;KF9-A;MONORDEN;MONORODENE
18 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 1mg
- 1
- 500μg
- 5mg
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0021-M001
- Product descriptionRadicicol ≥99%(HPLC)
- Packaging1mg
- Price$40
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0021-M005
- Product descriptionRadicicol ≥99%(HPLC)
- Packaging5mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2024AH
- Product descriptionRadicicol
- Packaging5mg
- Price$302
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4067
- Product descriptionRadicicol
- Packaging1mg
- Price$74
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBR162744
- Product descriptionRadicicol
- Packaging5mg
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number13089
- Product descriptionRadicicol ≥98%
- Packaging500μg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13089
- Product descriptionRadicicol ≥98%
- Packaging1mg
- Price$50
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number13089
- Product descriptionRadicicol ≥98%
- Packaging5mg
- Price$184
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0028899
- Product descriptionRadicicol >99.0%
- Packaging1mg
- Price$280
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0028899
- Product descriptionRadicicol >99.0%
- Packaging5mg
- Price$835
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberR2146
- Product descriptionRadicicol from Diheterospora chlamydosporia solid
- Packaging5mg
- Price$702
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberR2146
- Product descriptionRadicicol from Diheterospora chlamydosporia solid
- Packaging1mg
- Price$160
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product number553400
- Product descriptionRadicicol, Diheterospora chlamydosporia - CAS 12772-57-5 - Calbiochem
- Packaging500μg
- Price$144
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number1589
- Product descriptionRadicicol ≥98%(HPLC)
- Packaging1
- Price$147
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberR718235
- Product descriptionRadicicol
- Packaging1mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number045192
- Product descriptionRadicicol
- Packaging1mg
- Price$305
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CN2-0021-M001 | Radicicol ≥99%(HPLC) | 1mg | $40 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CN2-0021-M005 | Radicicol ≥99%(HPLC) | 5mg | $160 | 2021-12-16 | Buy |
| AK Scientific | 2024AH | Radicicol | 5mg | $302 | 2021-12-16 | Buy |
| ApexBio Technology | A4067 | Radicicol | 1mg | $74 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BR162744 | Radicicol | 5mg | $300 | 2021-12-16 | Buy |
| Cayman Chemical | 13089 | Radicicol ≥98% | 500μg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 13089 | Radicicol ≥98% | 1mg | $50 | 2024-03-01 | Buy |
| Cayman Chemical | 13089 | Radicicol ≥98% | 5mg | $184 | 2024-03-01 | Buy |
| ChemScene | CS-0028899 | Radicicol >99.0% | 1mg | $280 | 2021-12-16 | Buy |
| ChemScene | CS-0028899 | Radicicol >99.0% | 5mg | $835 | 2021-12-16 | Buy |
| Sigma-Aldrich | R2146 | Radicicol from Diheterospora chlamydosporia solid | 5mg | $702 | 2024-03-01 | Buy |
| Sigma-Aldrich | R2146 | Radicicol from Diheterospora chlamydosporia solid | 1mg | $160 | 2024-03-01 | Buy |
| Sigma-Aldrich | 553400 | Radicicol, Diheterospora chlamydosporia - CAS 12772-57-5 - Calbiochem | 500μg | $144 | 2024-03-01 | Buy |
| Tocris | 1589 | Radicicol ≥98%(HPLC) | 1 | $147 | 2021-12-16 | Buy |
| TRC | R718235 | Radicicol | 1mg | $150 | 2021-12-16 | Buy |
| Usbiological | 045192 | Radicicol | 1mg | $305 | 2021-12-16 | Buy |
Properties
Melting point :193.5°
alpha :D20 +203° (chloroform)
Boiling point :656.2±55.0 °C(Predicted)
Density :1.364±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :ethanol: 10 mg/mL
form :solid
pka :6.29±0.40(Predicted)
color :yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
alpha :D20 +203° (chloroform)
Boiling point :656.2±55.0 °C(Predicted)
Density :1.364±0.06 g/cm3(Predicted)
storage temp. :−20°C
solubility :ethanol: 10 mg/mL
form :solid
pka :6.29±0.40(Predicted)
color :yellow
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Safety Information
| Symbol(GHS): |
 
|
||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Danger | ||||||||||||||||||||||||||||
| Hazard statements: |
|
||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
Radicicol is a natural product derived from D. chlamydosporia with antibiotic, antifungal, and antimalarial properties. It binds and inhibits heat shock protein 90 (Hsp90) with nanomolar affinity. This interaction inhibits p23 from associating with Hsp90, suppresses signaling through HIF-1α, and produces decreased levels of progesterone receptor, Raf-1, p185erb82, and mutant p53. Radicicol also binds to and inhibits DNA topoisomerase type II proteins and GRP94 through an ATPase domain common to Hsp90.Related product price
- Tulathromycin A
$57-1802 - CASTANOSPERMINE
$33-1206 - BEZ235 (NVP-BEZ235, Dactolisib)
$25-1871.1
