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ChemicalBook >> CAS DataBase List >> RN486

RN486

RN486 price.
  • $42 - $2500
  • Product name: RN486
  • CAS: 1242156-23-5
  • MF: C35H35FN6O3
  • MW: 606.69
  • EINECS:200-110-4
  • MDL Number:MFCD24682729
  • Synonyms:RN486;6-cyclopropyl-8-fluoro-2-(2-(hydroxyMethyl)-3-(1-Methyl-5-((5-(4-Methylpiperazin-1-yl)pyridin-2-yl)aMiNA)-6-oxo-1,6-dihydropyridin-3-yl)phenyl)isoquiNAlin-1(2H)-one;6-cyclopropyl-8-fluoro-2-(2-(hydroxyMethyl)-3-(1-Methyl-5-(5-(4-Methylpiperazin-1-yl)pyridin-2-ylaMino)-6-oxo-1,6-dihydropyridin-3-yl)phenyl)isoquinolin-1(2H)-one;RN486/RN-486;RN468;6-Cyclopropyl-2-[3-[1,6-dihydro-1-methyl-5-[[5-(4-methyl-1-piperazinyl)-2-pyridinyl]amino]-6-oxo-3-pyridinyl]-2-(hydroxymethyl)phenyl]-8-fluoro-1(2H)-isoquinolinone;RN486 LM-2078;RN486 TFA Salt
Price48 Properties Safety Information Description
48 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • ApexBio Technology
  • Arctom
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • TRC
Package
  • 10mM*1mLinDMSO(Solution)
  • 10.00mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 1mg
  • 25.00mg
  • 10mM*1mLinDMSO
  • 250mg
  • 5mg
  • 10mg
  • 10mM(in1mLDMSO)
  • 25mg
  • 50mg
  • 100mg
  • 1G
  • Manufactureraablocks
  • Product numberAA009CBU
  • Product descriptionRN486 99%
  • Packaging10mg
  • Price$83
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009CBU
  • Product descriptionRN486 ≥98%
  • Packaging5mg
  • Price$42
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009CBU
  • Product descriptionRN486 99%
  • Packaging25mg
  • Price$122
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009CBU
  • Product descriptionRN486 99%
  • Packaging50mg
  • Price$207
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009CBU
  • Product descriptionRN486 99%
  • Packaging100mg
  • Price$351
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberH-8897
  • Product descriptionRN486 98%
  • Packaging25MG
  • Price$265
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberH-8897
  • Product descriptionRN486 98%
  • Packaging100MG
  • Price$750
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberH-8897
  • Product descriptionRN486 98%
  • Packaging5MG
  • Price$75
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberH-8897
  • Product descriptionRN486 98%
  • Packaging1G
  • Price$2450
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product numberY1887
  • Product descriptionRN486
  • Packaging25mg
  • Price$2475
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberY1887
  • Product descriptionRN486
  • Packaging10mg
  • Price$1265
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8636
  • Product descriptionRN486
  • Packaging5mg
  • Price$130
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8636
  • Product descriptionRN486
  • Packaging10mM(in1mLDMSO)
  • Price$175
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8636
  • Product descriptionRN486
  • Packaging25mg
  • Price$360
  • Updated2026-05-06
  • Buy
  • ManufacturerArctom
  • Product numberHY-18018
  • Product descriptionRN486 98.91%
  • Packaging25mg
  • Price$399
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-18018
  • Product descriptionRN486 98.91%
  • Packaging50mg
  • Price$637
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA009CBU RN486 99% 10mg $83 2026-05-28 Buy
aablocks AA009CBU RN486 ≥98% 5mg $42 2026-05-28 Buy
aablocks AA009CBU RN486 99% 25mg $122 2026-05-28 Buy
aablocks AA009CBU RN486 99% 50mg $207 2026-05-28 Buy
aablocks AA009CBU RN486 99% 100mg $351 2026-05-28 Buy
ACHEMBLOCK H-8897 RN486 98% 25MG $265 2026-05-27 Buy
ACHEMBLOCK H-8897 RN486 98% 100MG $750 2026-05-27 Buy
ACHEMBLOCK H-8897 RN486 98% 5MG $75 2026-05-27 Buy
ACHEMBLOCK H-8897 RN486 98% 1G $2450 2026-05-27 Buy
AK Scientific Y1887 RN486 25mg $2475 2021-12-16 Buy
AK Scientific Y1887 RN486 10mg $1265 2021-12-16 Buy
ApexBio Technology A8636 RN486 5mg $130 2026-05-06 Buy
ApexBio Technology A8636 RN486 10mM(in1mLDMSO) $175 2026-05-06 Buy
ApexBio Technology A8636 RN486 25mg $360 2026-05-06 Buy
Arctom HY-18018 RN486 98.91% 25mg $399 2026-05-26 Buy
Arctom HY-18018 RN486 98.91% 50mg $637 2026-05-26 Buy
Next Last

Properties

Boiling point :868.6±65.0 °C(Predicted)
Density :1.378±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥30.35 mg/mL in DMSO with gentle warming; insoluble in H2O; insoluble in EtOH
form :solid
pka :13.95±0.10(Predicted)
color :Off-white to light yellow
CAS DataBase Reference :1242156-23-5

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

RN 486 is a Bruton’s tyrosine kinase (Btk) inhibitor, blocking receptor cross-linking-induced degranulation in mast cells. May be used in the prevention of arthritis and other autoimmune diseases.

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Suppliers and manufacturers

career henan chemical co
RN486
$1.00
RN486 CAS: 1242156-23-5
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ROSEWA HOLDING GROUP CO.,LIMITED Chembest Research Laboratories Limited Wuhan Kaymke Chemical Co., Ltd., Bide Pharmatech Ltd.