SGI 7079
- $32 - $1000
- Product name: SGI 7079
- CAS: 1239875-86-5
- MF: C26H26FN7
- MW: 455.53
- EINECS:
- MDL Number:MFCD28963942
- Synonyms:3-[2-[[3-Fluoro-4-(4-methyl-1-piperazinyl)phenyl]amino]-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl]benzeneacetonitrile;SGI 7079;SGI-7079 /SGI7079;2-(3-(2-((3-Fluoro-4-(4-methylpiperazin-1-yl)phenyl)amino)-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl)acetonitrile;SGI-7079;SGI 7079;SGI7079;CS-2333;Benzeneacetonitrile, 3-[2-[[3-fluoro-4-(4-methyl-1-piperazinyl)phenyl]amino]-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-;Tyro3,inhibit,SGI 7079,Inhibitor,Axl,SGI-7079,Mer,TAM Receptor,SGI7079
18 prices
Selected condition:
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- Cayman Chemical
- Chemenu
- ChemScene
- DC Chemicals
- TRC
Package
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- ManufacturerAK Scientific
- Product number8620DG
- Product descriptionCID46870258
- Packaging1mg
- Price$133
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA771421
- Product descriptionSGI-7079 98+%
- Packaging2mg
- Price$57
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA771421
- Product descriptionSGI-7079 98+%
- Packaging5mg
- Price$83
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA771421
- Product descriptionSGI-7079 98+%
- Packaging10mg
- Price$130
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA771421
- Product descriptionSGI-7079 98+%
- Packaging50mg
- Price$425
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA771421
- Product descriptionSGI-7079 98+%
- Packaging100mg
- Price$552
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0004682
- Product description2-(3-(2-((3-FLUORO-4-(4-METHYLPIPERAZIN-1-YL)PHENYL)AMINO)-5-METHYL-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)PHENYL)ACETONITRILE 95.00%
- Packaging5MG
- Price$499.22
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number20111
- Product descriptionSGI-7079 ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number20111
- Product descriptionSGI-7079 ≥98%
- Packaging5mg
- Price$131
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number20111
- Product descriptionSGI-7079 ≥98%
- Packaging10mg
- Price$243
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number20111
- Product descriptionSGI-7079 ≥98%
- Packaging25mg
- Price$456
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM152411
- Product description2-(3-(2-((3-fluoro-4-(4-methylpiperazin-1-yl)phenyl)amino)-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl)acetonitrile 98%
- Packaging100mg
- Price$471
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5607
- Product descriptionSGI-7079 99.65%
- Packaging5mg
- Price$108
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5607
- Product descriptionSGI-7079 99.65%
- Packaging10mg
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5607
- Product descriptionSGI-7079 99.65%
- Packaging50mg
- Price$660
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5607
- Product descriptionSGI-7079 99.65%
- Packaging100mg
- Price$960
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 8620DG | CID46870258 | 1mg | $133 | 2021-12-16 | Buy |
Ambeed | A771421 | SGI-7079 98+% | 2mg | $57 | 2021-12-16 | Buy |
Ambeed | A771421 | SGI-7079 98+% | 5mg | $83 | 2021-12-16 | Buy |
Ambeed | A771421 | SGI-7079 98+% | 10mg | $130 | 2021-12-16 | Buy |
Ambeed | A771421 | SGI-7079 98+% | 50mg | $425 | 2021-12-16 | Buy |
Ambeed | A771421 | SGI-7079 98+% | 100mg | $552 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | INB0004682 | 2-(3-(2-((3-FLUORO-4-(4-METHYLPIPERAZIN-1-YL)PHENYL)AMINO)-5-METHYL-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)PHENYL)ACETONITRILE 95.00% | 5MG | $499.22 | 2021-12-16 | Buy |
Cayman Chemical | 20111 | SGI-7079 ≥98% | 1mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 20111 | SGI-7079 ≥98% | 5mg | $131 | 2024-03-01 | Buy |
Cayman Chemical | 20111 | SGI-7079 ≥98% | 10mg | $243 | 2024-03-01 | Buy |
Cayman Chemical | 20111 | SGI-7079 ≥98% | 25mg | $456 | 2024-03-01 | Buy |
Chemenu | CM152411 | 2-(3-(2-((3-fluoro-4-(4-methylpiperazin-1-yl)phenyl)amino)-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl)acetonitrile 98% | 100mg | $471 | 2021-12-16 | Buy |
ChemScene | CS-5607 | SGI-7079 99.65% | 5mg | $108 | 2021-12-16 | Buy |
ChemScene | CS-5607 | SGI-7079 99.65% | 10mg | $180 | 2021-12-16 | Buy |
ChemScene | CS-5607 | SGI-7079 99.65% | 50mg | $660 | 2021-12-16 | Buy |
ChemScene | CS-5607 | SGI-7079 99.65% | 100mg | $960 | 2021-12-16 | Buy |
Properties
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml
form :A crystalline solid
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml
form :A crystalline solid
Safety Information
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Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
SGI-7079 is an inhibitor of the receptor tyrosine kinase Axl. It inhibits proliferation of inflammatory breast cancer cells (IC50s = 0.43 and 0.15 μM for SUM149 and KPL-4 cells, respectively), decreases invasion, and halts the cell cycle in the G1 phase. SGI-7079 synergistically increases the potency of erlotinib on EGFR inhibition. In a mouse xenograft model of non-small cell lung cancer, SGI-7079 dose-dependently inhibits tumor growth, an effect that is greater when used in combination with erlotinib.Related product price
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