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ChemicalBook >> CAS DataBase List >> TRICHOSTATIN A

TRICHOSTATIN A

TRICHOSTATIN A price.
  • $56 - $4500
  • Product name: TRICHOSTATIN A
  • CAS: 58880-19-6
  • MF: C17H22N2O3
  • MW: 302.37
  • EINECS:611-758-2
  • MDL Number:MFCD03848392
  • Synonyms:7-(4-(dimethylamino)phenyl)-n-hydroxy-4,6-dimethyl-7-oxo-4-heptadienamide ;7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6R-DIMETHYL-7-OXO-2E,4E-HEPTADIENAMIDE;4,6-DIMETHYL-7-[P-DIMETHYLAMINOPHENYL]-7-OXAHEPTA-2,4-DIENOHYDROXAMIC ACID;4,6-DIMETHYL-7-[P-DIMETHYLAMINOPHENYL]-7-OXOHEPTA-2,4-DIENOHYDROXAMIC ACID;Trichostatin A from Streptomyces platensis;[r-(e,e)]-7-[4-(dimethylamino)phenyl]-n-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide;7-(4-DIMETHYLAMINOPHENYL)-N-HYDROXY-4,6-DIMETHYL-7-OXO-HEPTA-2,4-DIENAMIDE;TSA, [R-(E,E)]-7-[4-(Dimethylamino)phenyl]-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
49 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • Arctom
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Labseeker
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
Package
  • 1mg
  • 1
  • 500μg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 1g
  • 200μL
  • 10mM(in 1mL DMSO)
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0108-M001
  • Product descriptionTrichostatin A ≥95%(HPLC)
  • Packaging1mg
  • Price$80
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberM984
  • Product descriptionTrichostatin A
  • Packaging5mg
  • Price$294
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberM984
  • Product descriptionTrichostatin A
  • Packaging10mg
  • Price$401
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberM984
  • Product descriptionTrichostatin A
  • Packaging25mg
  • Price$883
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA725112
  • Product description(R,2E,4E)-7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide 98+%
  • Packaging2mg
  • Price$129
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA725112
  • Product description(R,2E,4E)-7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide 98+%
  • Packaging5mg
  • Price$234
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA725112
  • Product description(R,2E,4E)-7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide 98+%
  • Packaging10mg
  • Price$378
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA725112
  • Product description(R,2E,4E)-7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide 98+%
  • Packaging25mg
  • Price$911
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA725112
  • Product description(R,2E,4E)-7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide 98+%
  • Packaging50mg
  • Price$1561
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8183
  • Product descriptionTrichostatinA(TSA)
  • Packaging1mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8183
  • Product descriptionTrichostatinA(TSA)
  • Packaging10mM(in 1mL DMSO)
  • Price$210
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8183
  • Product descriptionTrichostatinA(TSA)
  • Packaging100mg
  • Price$1800
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60041
  • Product descriptionTrichostatin A
  • Packaging5mg
  • Price$428
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberAT45107
  • Product descriptionTrichostatin A
  • Packaging1mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberAT45107
  • Product descriptionTrichostatin A
  • Packaging2mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberAT45107
  • Product descriptionTrichostatin A
  • Packaging5mg
  • Price$320
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CN2-0108-M001 Trichostatin A ≥95%(HPLC) 1mg $80 2021-12-16 Buy
AK Scientific M984 Trichostatin A 5mg $294 2021-12-16 Buy
AK Scientific M984 Trichostatin A 10mg $401 2021-12-16 Buy
AK Scientific M984 Trichostatin A 25mg $883 2021-12-16 Buy
Ambeed A725112 (R,2E,4E)-7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide 98+% 2mg $129 2021-12-16 Buy
Ambeed A725112 (R,2E,4E)-7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide 98+% 5mg $234 2021-12-16 Buy
Ambeed A725112 (R,2E,4E)-7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide 98+% 10mg $378 2021-12-16 Buy
Ambeed A725112 (R,2E,4E)-7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide 98+% 25mg $911 2021-12-16 Buy
Ambeed A725112 (R,2E,4E)-7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxohepta-2,4-dienamide 98+% 50mg $1561 2021-12-16 Buy
ApexBio Technology A8183 TrichostatinA(TSA) 1mg $60 2021-12-16 Buy
ApexBio Technology A8183 TrichostatinA(TSA) 10mM(in 1mL DMSO) $210 2021-12-16 Buy
ApexBio Technology A8183 TrichostatinA(TSA) 100mg $1800 2021-12-16 Buy
Arctom CFN60041 Trichostatin A 5mg $428 2021-12-16 Buy
Biosynth Carbosynth AT45107 Trichostatin A 1mg $100 2021-12-16 Buy
Biosynth Carbosynth AT45107 Trichostatin A 2mg $160 2021-12-16 Buy
Biosynth Carbosynth AT45107 Trichostatin A 5mg $320 2021-12-16 Buy

Properties

Melting point :140-143℃
alpha :D20.5 +62.8° ±1.1° (c = 1.007 in ethanol)
Density :1.139
refractive index :136 ° (C=0.3, MeOH)
storage temp. :-20°C
solubility :ethanol: 1 mg/mL
pka :8.93±0.23(Predicted)
form :Off-white lyophilized solid
color :Tan
Merck :14,9649
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChIKey :ZWGICMNKJBUOHG-RCXLNATQSA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Trichostatin A is a potent, reversible inhibitor of histone deacetylase (HDAC). In human Jurkat T cells, trichostatin A arrests cell cycle progression in G1 and inhibits the activity of the HDAC1 with an IC50 value of 70 nM. Trichostatin A selectively inhibits the removal of acetyl groups from the amino-terminal lysine residues of core histones, which modulates the access of transcription factors to the underlying genomic DNA.

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