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ChemicalBook >> CAS DataBase List >> U-46619

U-46619

U-46619 price.
  • $97 - $1610
  • Product name: U-46619
  • CAS: 56985-40-1
  • MF: C21H34O4
  • MW: 350.49
  • EINECS:
  • MDL Number:MFCD00135238
  • Synonyms:9,11-DIDEOXY-11ALPHA,9ALPHA-EPOXYMETHANO;9,11-DIDEOXY-11A,9A-EPOXYMETHANO-*PROSTA GLANDIN F2A;9,11-dideoxy-11α,9α-epoxymethanoprostaglandin f2α;9,11-dideoxy-11alpha,9alpha-epoxymethanoprostaglandin F2a;(5Z)-7-[(1R,4S,5S,6R)-6-[(1E,3S)-3-Hydroxy-1-octenyl]-2 -oxabicyclo[2.2.1]hept-5-yl]-5-heptenoic acid;(5Z)-7-[(1R,4S)-6β-[(1E,3S)-3-Hydroxy-1-octenyl]-2-oxabicyclo[2.2.1]heptan-5α-yl]-5-heptenoic acid;(Z)-7-[(1R,4S)-6β-[(E,S)-3-Hydroxy-1-octenyl]-2-oxabicyclo[2.2.1]hept-5α-yl]-5-heptenoic acid;11α,9α-Epoxymethanoprostaglandin H2
17 prices
Selected condition:
Brand
  • AHH
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Cayman Chemical
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 1MG
  • 2.5mg
  • 1
  • 0.005g
  • 5MG
  • 10MG
  • ManufacturerAHH
  • Product numberMT-08967
  • Product description9,11-Dideoxy-9alpha,11alpha-methanoepoxyPGF2alpha 98%
  • Packaging0.005g
  • Price$355
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberLIP0000015
  • Product description9,11-DIDEOXY-9ALPHA,11ALPHA-METHANO-EPOXY PROSTAGLANDIN F2ALPHA 95.00%
  • Packaging1MG
  • Price$628.2
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberLIP0000015
  • Product description9,11-DIDEOXY-9ALPHA,11ALPHA-METHANO-EPOXY PROSTAGLANDIN F2ALPHA 95.00%
  • Packaging5MG
  • Price$960.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberLIP0000015
  • Product description9,11-DIDEOXY-9ALPHA,11ALPHA-METHANO-EPOXY PROSTAGLANDIN F2ALPHA 95.00%
  • Packaging10MG
  • Price$1205.47
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB6890
  • Product descriptionU-46619
  • Packaging5mg
  • Price$437
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number16450
  • Product descriptionU-46619 ≥98%
  • Packaging1mg
  • Price$97
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16450
  • Product descriptionU-46619 ≥98%
  • Packaging5mg
  • Price$437
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number16450
  • Product descriptionU-46619 ≥98%
  • Packaging10mg
  • Price$728
  • Updated2024-03-01
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number72959
  • Product descriptionU-46619
  • Packaging2.5mg
  • Price$650
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number538944
  • Product descriptionU-46619
  • Packaging1mg
  • Price$242
  • Updated2022-05-15
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberD8174
  • Product description9,11-Dideoxy-11α,9α-epoxymethanoprostaglandin F2α solution, 10 mg/mL in methyl acetate
  • Packaging1mg
  • Price$339
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberD8174
  • Product description9,11-Dideoxy-11α,9α-epoxymethanoprostaglandin F2α solution, 10 mg/mL in methyl acetate
  • Packaging5mg
  • Price$1330
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberD8174
  • Product description9,11-Dideoxy-11α,9α-epoxymethanoprostaglandin F2α solution, 10 mg/mL in methyl acetate
  • Packaging10mg
  • Price$1610
  • Updated2023-06-20
  • Buy
  • ManufacturerTocris
  • Product number1932
  • Product descriptionU-46619 ≥98%(HPLC)
  • Packaging1
  • Price$161
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberU100210
  • Product descriptionU-46619
  • Packaging2.5mg
  • Price$325
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number256990
  • Product descriptionU 46619
  • Packaging1mg
  • Price$403
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-08967 9,11-Dideoxy-9alpha,11alpha-methanoepoxyPGF2alpha 98% 0.005g $355 2021-12-16 Buy
American Custom Chemicals Corporation LIP0000015 9,11-DIDEOXY-9ALPHA,11ALPHA-METHANO-EPOXY PROSTAGLANDIN F2ALPHA 95.00% 1MG $628.2 2021-12-16 Buy
American Custom Chemicals Corporation LIP0000015 9,11-DIDEOXY-9ALPHA,11ALPHA-METHANO-EPOXY PROSTAGLANDIN F2ALPHA 95.00% 5MG $960.5 2021-12-16 Buy
American Custom Chemicals Corporation LIP0000015 9,11-DIDEOXY-9ALPHA,11ALPHA-METHANO-EPOXY PROSTAGLANDIN F2ALPHA 95.00% 10MG $1205.47 2021-12-16 Buy
ApexBio Technology B6890 U-46619 5mg $437 2021-12-16 Buy
Cayman Chemical 16450 U-46619 ≥98% 1mg $97 2024-03-01 Buy
Cayman Chemical 16450 U-46619 ≥98% 5mg $437 2024-03-01 Buy
Cayman Chemical 16450 U-46619 ≥98% 10mg $728 2024-03-01 Buy
Medical Isotopes, Inc. 72959 U-46619 2.5mg $650 2021-12-16 Buy
Sigma-Aldrich 538944 U-46619 1mg $242 2022-05-15 Buy
Sigma-Aldrich D8174 9,11-Dideoxy-11α,9α-epoxymethanoprostaglandin F2α solution, 10 mg/mL in methyl acetate 1mg $339 2024-03-01 Buy
Sigma-Aldrich D8174 9,11-Dideoxy-11α,9α-epoxymethanoprostaglandin F2α solution, 10 mg/mL in methyl acetate 5mg $1330 2024-03-01 Buy
Sigma-Aldrich D8174 9,11-Dideoxy-11α,9α-epoxymethanoprostaglandin F2α solution, 10 mg/mL in methyl acetate 10mg $1610 2023-06-20 Buy
Tocris 1932 U-46619 ≥98%(HPLC) 1 $161 2021-12-16 Buy
TRC U100210 U-46619 2.5mg $325 2021-12-16 Buy
Usbiological 256990 U 46619 1mg $403 2021-12-16 Buy

Properties

Boiling point :519.7±30.0 °C(Predicted)
Density :1.092±0.06 g/cm3(Predicted)
Flash point :-10 °C
storage temp. :-20°C
solubility :≥100 mg/mL in DMSO, ≥100 mg/mL in Ethanol, ≥100 mg/mL in DMF, ≥2 mg/mL in PBS pH 7.2
pka :4.76±0.10(Predicted)
form :solution
BRN :4267334

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H336 May cause drowsiness or dizziness Specific target organ toxicity,single exposure; Narcotic effects Category 3 Warning P261, P271, P304+P340, P312,P403+P233, P405, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

U-46619 is a stable analog of the endoperoxide prostaglandin H2, and a TP receptor agonist. It exhibits properties similar to thromboxane A2, causing platelet shape change and aggregation, and contraction of vascular smooth muscle. Mean EC50 values for shape change in human, rat, and rabbit platelets are 4.8, 6.0, and 7.3 nM respectively, and for aggregation are 82, 145, and 65 nM, respectively.

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