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ChemicalBook >> CAS DataBase List >> ml390

ml390

ml390 price.
  • $49 - $410
  • Product name: ml390
  • CAS: 2029049-79-2
  • MF: C21H21F3N2O3
  • MW: 406.4
  • EINECS:-0
  • MDL Number:
  • Synonyms:ml390;Benzamide, N-[3-oxo-3-[[(1R)-1,2,3,4-tetrahydro-1-naphthalenyl]amino]propyl]-4-(trifluoromethoxy)-;ER-HoxA9,Dihydroorotate Dehydrogenase,inhibit,AML,ML 390,differentiatio,U937,DHODH,ML390,myeloid,ML-390,Inhibitor,THP1;(R)-N-(3-Oxo-3-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)propyl)-4-(trifluoromethoxy)benzamide
Price9 Properties Safety Information Description
9 prices
Selected condition：
Brand
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • ManufacturerApexBio Technology
  • Product numberB7824
  • Product descriptionML390
  • Packaging5mg
  • Price$190
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21395
  • Product descriptionML-390 ≥98%
  • Packaging5mg
  • Price$49
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21395
  • Product descriptionML-390 ≥98%
  • Packaging10mg
  • Price$87
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21395
  • Product descriptionML-390 ≥98%
  • Packaging25mg
  • Price$190
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21395
  • Product descriptionML-390 ≥98%
  • Packaging50mg
  • Price$286
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5978
  • Product descriptionML390 98.77%
  • Packaging5mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5978
  • Product descriptionML390 98.77%
  • Packaging10mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5978
  • Product descriptionML390 98.77%
  • Packaging50mg
  • Price$230
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-5978
  • Product descriptionML390 98.77%
  • Packaging100mg
  • Price$410
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ApexBio Technology B7824 ML390 5mg $190 2021-12-16 Buy
Cayman Chemical 21395 ML-390 ≥98% 5mg $49 2024-03-01 Buy
Cayman Chemical 21395 ML-390 ≥98% 10mg $87 2024-03-01 Buy
Cayman Chemical 21395 ML-390 ≥98% 25mg $190 2024-03-01 Buy
Cayman Chemical 21395 ML-390 ≥98% 50mg $286 2024-03-01 Buy
ChemScene CS-5978 ML390 98.77% 5mg $70 2021-12-16 Buy
ChemScene CS-5978 ML390 98.77% 10mg $90 2021-12-16 Buy
ChemScene CS-5978 ML390 98.77% 50mg $230 2021-12-16 Buy
ChemScene CS-5978 ML390 98.77% 100mg $410 2021-12-16 Buy

Properties

Boiling point :599.7±50.0 °C(Predicted)
Density :1.31±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥40.6 mg/mL in DMSO; insoluble in H2O; ≥17.47 mg/mL in EtOH
form :solid
pka :13.65±0.46(Predicted)
color :White to off-white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

ML-390 is an inhibitor of dihydroorotate dehydrogenase (DHODH), the enzyme that converts dihydroorotate to orotate during de novo pyrimidine synthesis. In acute myeloid leukemia, leukemic myeloblast development is halted at an immature stage leading to perpetual self-renewal rather than differentiation. ML-390 induces differentiation in the acute myeloid leukemia cell lines U937 (murine) and THP-1 (human) cell lines with an EC50 value of approximately 2 μM.

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Suppliers and manufacturers

BOC Sciences
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InvivoChem
Aladdin Scientific Shanghai Beckham Medical Technology Co., Ltd Shanghai Chaolan Chemical Technology Center Beijing Solarbio Science & Tecnology Co., Ltd. Twochem Co.Ltd. Guangzhou Tomums Life Science Co., Ltd. Tianjin Kaifu Pharmaceutical Technology Co., Ltd.