链丝菌素硫酸盐
中文名称 | 链丝菌素硫酸盐 |
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中文同义词 | 链丝菌素硫酸盐;NOURSEOTHRICIN SULFATE 诺尔丝菌素;诺尔丝菌素;硫酸诺尔丝菌素;诺尔丝菌素硫酸盐;诺尔丝菌素硫酸盐(链丝菌素硫酸盐);链丝菌素 |
英文名称 | NOURSEOTHRICIN SULFATE |
英文同义词 | STREPTOTHRICIN;NOURSEOTHRICIN SULPHATE;nourseothricin,sulfate(salt);NOURSEOTHRICIN SULFATE 90+%;Streptothricin sulfate;Nourseothricin (streptothricin) sulfate;NOURSEOTHRICIN SULFATE;UDVWKDBCMFLRQW-TWRCRAKCSA-N |
CAS号 | 96736-11-7 |
分子式 | C44H82N18O21S |
分子量 | 1231.29488 |
EINECS号 | |
相关类别 | |
Mol文件 | 96736-11-7.mol |
结构式 |
链丝菌素硫酸盐 性质
储存条件 | 2-8°C |
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溶解度 | 在水中的溶解度为200mg/mL |
形态 | 固体 |
颜色 | 白色至浅棕色 |
Escherichia coli resistance to neurosporin can be sensitive to resistant strains by eliminating their outer membrane resistance. The polycationic antibiotic, Nourseothricin, represents a mixture of several Streptothricins, mainly D and F. Obviously, although very slowly, it can pass the outer membrane via the porin pores. It has been shown earlier that Nourseothricin is able to generate some kind of channels into the outer membrane through which it can pass the cell wall. On the other hand, there are indications that resistant strains containing a Nourseothricin-inactivating acetyl transferase possess an additional protecting system, namely a reduced penetrability of the outer membrane.
Nourseothricin is preferentially excreted via kidney and signs of nephrotoxicity can be observed after its administration. Renal handling of Nourseothricin is characterized in experiments on renal cortical slices under various experimental conditions. Following administration in vivo the renal tubular transport system for organic anions (p-aminohippurate, PAH) is not influenced by Nourseothricin. There is a high degree of accumulation of Nourseothricin in renal cortical slices. In contrast to PAH accumulation there is no influence of nitrogen atmosphere, simultaneous administration of PAH, probenecid or trishydroxyaminomethane on Nourseothricin accumulation. Age dependent differences in Nourseothricin accumulation does not exist.
安全信息
危险品标志 | Xn |
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危险类别码 | 22-36/37/38 |
安全说明 | 26-36 |
WGK Germany | 3 |
RTECS号 | RD4240000 |
F | 10 |
海关编码 | 2941900000 |
提供商 | 语言 |
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英文
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更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
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2024/08/19 | HY-129065 | Nourseothricin sulfate | 1 mg | 250元 | |
2024/08/19 | HY-129065 | 链丝菌素硫酸盐 Nourseothricin sulfate | 96736-11-7 | 5mg | 500元 |