ChemicalBook CAS DataBase List 1-(1-chloroethyl)-4-(trifluoromethoxy)benzene

1-(1-chloroethyl)-4-(trifluoromethoxy)benzene synthesis

1synthesis methods

Product Name:1-(1-chloroethyl)-4-(trifluoromethoxy)benzene
CAS Number:306296-69-5
Molecular formula:C9H8ClF3O
Molecular Weight:224.61

85013-98-5 Synthesis

85013-98-5
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1-(1-chloroethyl)-4-(trifluoromethoxy)benzene

306296-69-5
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Yield:-

Steps:

Multi-step reaction with 2 steps
1: sodium tetrahydridoborate; ethanol / 0 - 20 °C
2: thionyl chloride; pyridine / diethyl ether / 0 - 20 °C

References:

Friede, Nathan C.;Minteer, Shelley D.;Sigman, Matthew S.;Tang, Tianhua [European Journal of Organic Chemistry,2022,vol. 2022,# 14,art. no. E202200064]

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