1,1'-(dodecylimino)dipropan-2-ol synthesis

Yield:1541-66-8 90.02%

Reaction Conditions:

in ethanol at 80; for 12 h;

Steps:

Syntheses of Cm-n-Cm[iso-Pr(OH)]2 Surfactants

To achieve the substitution reaction (Scheme 1a), samples of(0.12 mol) 29.88 g of 1-bromododecane and (0.10 mol)10.10 g of diisopropylamine were refluxed with (4.35 mol)200 mL of ethanol at 80 C for 12 h. After the completionof the reaction, a white, paste-like substance was collectedby removing ethanol, and then washed with acetone threetimes. N,N0-bis(2-hydroxypropyl) dodecylamine wasobtained and its yield was approximately 90.02%. To prepareN,N0-bis(2-hydroxypropyl) tetradecylamine, (0.12 mol)33.24 g of 1-bromotetradecane, and (0.10 mol) 10.10 g ofdiisopropylamine in (4.35 mol) 200 mL of ethanol werereacted according to the method described above. The yieldof N,N0-bis(2-hydroxypropyl) tetradecylamine was approximately 87.05%

References:

Bai, Yun;Pu, Chunsheng;Liu, Shuai;Gao, Xiang;Chen, Gang [Journal of Surfactants and Detergents,2021,vol. 24,# 2,p. 199 - 208]