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ChemicalBook CAS DataBase List 1,3,4-Tri-O-acetyl-2-deoxy-2-fluoro-L-fucose
188783-78-0

1,3,4-Tri-O-acetyl-2-deoxy-2-fluoro-L-fucose synthesis

4synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: zinc; 2-methylimidazole / tetrahydrofuran / Reflux
2: boron trifluoride diethyl etherate; xenon fluoride / diethyl ether; benzene
3: hydrogenchloride / water / 1 h / 90 °C

References:

Seattle Genetics, Inc.;Alley, Stephen C.;Jeffrey, Scott C.;Sussman, Django;Benjamin, Dennis R.;Toki, Brian;Burke, Patrick J. US2014/31536, 2014, A1