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ChemicalBook CAS DataBase List 1-(3-bromo-2-hydroxy-5-methylphenyl)ethanone
56609-15-5

1-(3-bromo-2-hydroxy-5-methylphenyl)ethanone synthesis

6synthesis methods
Preparation by Fries rearrangement of 2-bromo-4- methyl-phenyl acetate,
with aluminium chloride without solvent at 110° or in refluxing nitrobenzene (90%)
with zinc chloride or boron trifluoride in nitrobenzene at 100° (80–85%)
with ferric chloride or stannic chloride in nitrobenzene at 100° (55–70%).
1450-72-2 Synthesis
1-(2-Hydroxy-5-methylphenyl)ethanone

1450-72-2
201 suppliers
$6.00/1g

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Yield:56609-15-5 93%

Reaction Conditions:

with N-Bromosuccinimide in N,N-dimethyl-formamide;

References:

Dijkstra, P. J.;Steen, B. J. van;Hams, B. H. M.;Hertog, H. J. den;Reinhoudt, D. N. [Tetrahedron Letters,1986,vol. 27,# 27,p. 3183 - 3186]