1-(3-Bromoprop-1-yn-1-yl)-4-fluorobenzene synthesis
- Product Name:1-(3-Bromoprop-1-yn-1-yl)-4-fluorobenzene
- CAS Number:40274-29-1
- Molecular formula:C9H6BrF
- Molecular Weight:213.05
80151-28-6
44 suppliers
inquiry
40274-29-1
20 suppliers
inquiry
Yield:40274-29-1 100%
Reaction Conditions:
with carbon tetrabromide;triphenylphosphine in tetrahydrofuran at 20;
Steps:
8.2 2. Procedure jbr the preparation of compound 5HZ
To a solution of compound 5 la (1.0 g, &67 mmci) in TNT (15 mLI was added PHi3 (1.92g 7 34 minol) then CEn (2 2 1 g 6 67 mrnol) and the mixtuic wa’‘dined at RT O ernigMTLC (PE:EA=4: I) showed that the starting material was consumed, PB (30 .mL) was added and the mixture was filtered. The filtrate was concentrated in vacuo and the residue was purifiul by chi om ilogi aphy (1OOf PE) to gin compound 51 b (I S g 100% ) as a colorless oil.
References:
WO2015/3223,2015,A1 Location in patent:Page/Page column 57
227954-23-6
0 suppliers
inquiry
40274-29-1
20 suppliers
inquiry
352-34-1
380 suppliers
$7.00/5g
40274-29-1
20 suppliers
inquiry
766-98-3
251 suppliers
$6.00/1g
40274-29-1
20 suppliers
inquiry